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Pain clinical trials

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NCT ID: NCT03227614 Enrolling by invitation - Pain Clinical Trials

Friends/Family in the Abortion Procedure Room (FAIR)

FAIR
Start date: July 18, 2017
Phase: N/A
Study type: Interventional

This study aims to explore patient, support person, and health care providers' experience and satisfaction with social support in the abortion procedure room. Although some providers do allow a support person in the abortion procedure room, no study has formally examined the effects of this practice. If this study demonstrates higher patient satisfaction and lower perceptions of pain and anxiety levels in patients who have social support in the in-clinic abortion procedure room, this could change standard procedures in the in-clinic abortion procedure room, allowing for more positive patient experiences.

NCT ID: NCT03070054 Enrolling by invitation - Pain Clinical Trials

LIA in Hip Arthroscopy Patients

Start date: June 2016
Phase: Early Phase 1
Study type: Interventional

The investigator's are conducting a randomized, blinded study to determine if the extra-capsular local infiltration analgesic (LIA) administration of 20ml 0.25% bupivacaine-epinephrine can improve the postoperative pain management of hip arthroscopy patients. Participants will be randomly assigned to the LIA group or non-LIA group prior to surgery. Participants, anesthesiologists and PACU nurses will be blinded to group assignment, however the surgeon administering the LIA will be unblinded.

NCT ID: NCT02902770 Enrolling by invitation - Pain Clinical Trials

Intravenous Lidocaine and Ketorolac for Pain Management

Start date: October 2016
Phase: Phase 4
Study type: Interventional

The literature regarding analgesic modalities, their combinations and routes of administrations for patients with pain related to renal colic is expanding. NSAID's (IV ketorolac) and opioids (morphine) constitutes the mainstay of treatment of renal colic either alone or in combinations. Despite their synergism and analgesic superiority when administered together, both classes of these medications possess a set of unfavorable side effects that limit their use. Emerging data of the use of IV lidocaine for patients with renal colic demonstrated good analgesic efficacy and safety profile. However, none of the trials directly compared lidocaine to ketorolac or the combination of both as viable options in patients unable to tolerate or to have serious contraindications to opioids. We designed a double-blinded, randomized, controlled trial to evaluate analgesic efficacy, safety and feasibility of non-opioid analgesics and their combinations in patients with renal colic. The hypothesis and proposed study will try to determine if a combination of IV lidocaine and reduced dose of IV ketorolac is superior to either drug alone and if this non-opioid analgesic modality is effective for controlling pain of renal colic origin.

NCT ID: NCT02897934 Enrolling by invitation - Breast Cancer Clinical Trials

CWI and Discharge After Breast Cancer Surgery

Start date: August 2016
Phase: N/A
Study type: Observational

The objectives of this work are threefold: 1. To evaluate the analgesic efficacy of CWI in women discharged within 23 hours of major breast cancer surgery 2. To evaluate objective indices of patient recovery following anaesthesia and surgery in a 23 hour model of care 3. To evaluate patient satisfaction with their care pathway

NCT ID: NCT02809846 Enrolling by invitation - Prostate Cancer Clinical Trials

Quell Opioid Reduction and Pain Relief in Patients With Cancer

Start date: July 2016
Phase: Phase 3
Study type: Interventional

To study effects Quell has on opioid consumption and pain relief in patients with cancer.

NCT ID: NCT02752854 Enrolling by invitation - Pain Clinical Trials

Pain Threshold Measurements in High and Low Altitude Among Healthy Volunteer Adults: A Comparative Study

Start date: April 2015
Phase: N/A
Study type: Observational

one measurement of pain threshold in high altitude and in low altitude using pressure algometer and Situational pain scale.

NCT ID: NCT02751268 Enrolling by invitation - Pain Clinical Trials

Effect of Infraorbital and Infratrochlear Nerve Block on Emergence Agitation in Patients Undergoing Septorhinoplasty

Start date: April 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether bilateral infraorbital and infratrochlear nerve block in patients undergoing septorhinoplasty are effective in preventing emergence agitation.

NCT ID: NCT02732262 Enrolling by invitation - Pain Clinical Trials

Optimal Dose of i.v Oxycodone for Postoperative Pain

Start date: April 2016
Phase: Phase 3
Study type: Interventional

Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe. The aim of this study is to evaluate the optimal dose of intravenous oxycodone for pain control after laparoscopic colorectal surgery in Korean.

NCT ID: NCT02720315 Enrolling by invitation - Pain Clinical Trials

Intensive Cryotherapy in the Emergency Department for Acute Musculoskeletal Injuries

Start date: February 2016
Phase: N/A
Study type: Interventional

Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment. Within the orthopedic literature, there is robust body of research supporting the use of cryotherapy for post-operative patients and injured athletes. However, within the emergency department (ED), studies have been focused on pharmacologic analgesia. The absence of evidence on optimal method or impact of ice therapy for acute MSK injuries contributes to inconsistent practice patterns that may impede symptom control or increase narcotic usage. The specific aim of the ICED investigation is to evaluate the effectiveness of intensive cryotherapy for the treatment of pain due to acute MSK injuries treated in the ED. Secondary outcomes include length-of-stay (LOS), patient satisfaction, and narcotic usage.

NCT ID: NCT02707029 Enrolling by invitation - Pain Clinical Trials

Clinical and Scientific Assessment of Pain and Painful Disorders

Start date: February 25, 2016
Phase: N/A
Study type: Observational

Background: Researchers want to better understand pain by studying people with and without different kinds of pain. To do this, researchers will expose people to pleasant and unpleasant sensations. They will ask them questions about their pain. Researchers also want to see if these people are eligible for other research studies at the National Center for Complementary and Integrative Health. Objectives: To study the experience of pain. Also to find people eligible to join other NIH studies. Eligibility: People 12 years and older with and without pain disorders. Design: Participants will be screened by phone. Participants will have one required visit. This may include: - Medical history - Physical exam - Questionnaires about themselves and their pain experience - Blood and urine tests - MRI: They will lie on a table that slides into a cylinder. They will feel different sensations while completing tasks on a computer. This lasts 15 minutes to 2 hours. - Quantitative sensory testing: They will be exposed to different pictures, sounds, tastes, and smells. They will also be exposed to pleasant and unpleasant sensations. These could include: - Burning, itching, or cold sensations - Pinpricks - Pressure and pinches - Electrocardiogram: Stickers on the chest record heart activity. - Straps placed around the chest to measure breathing. - Small sensors on the fingers or palms to measure pulse and sweating. Over the next 3 months, participants may have up to 4 other study visits. These last 2 to 4 hours each. They include repeats of some of the tests in the required visit. Participants may be recorded at the visits.