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Chronic Pain clinical trials

View clinical trials related to Chronic Pain.

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NCT ID: NCT03670147 Not yet recruiting - Chronic Pain Clinical Trials

Paresthesia Free Spinal Cord Stimulation (PF-SCS)

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The goal is to document efficacy of PF-SCS therapy in a blinded fashion and better understand how SCS therapy works in the clinical setting. Overall the investigators hope to improve patient care and selection of candidates who have the best potential for effective pain relief from an expensive and invasive therapy.

NCT ID: NCT03669939 Not yet recruiting - Chronic Pain Clinical Trials

Toward Safer Opioid Prescribing for Chronic Pain in High Risk Populations

TOWER
Start date: September 24, 2018
Phase:
Study type: Observational

The overarching plan for TOWER is to develop and test an algorithmic version of the Center for Disease Control Guidelines (CDCG) tailored for a specific primary care setting, the HIV primary care clinic. This CDCG intervention incorporates communication and implementation strategies tailored for the HIV primary care setting, and enabled with technology (an app for use by patients and EMR tools for providers).

NCT ID: NCT03666455 Not yet recruiting - Chronic Pain Clinical Trials

Treating Pain With Acceptance and Commitment Therapy Trial

T-PACT
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The long-term goal is to define best practices for diminishing the risk of high opioid doses used to treat chronic non-cancer pain (CNCP) patients while optimizing pain outcomes and functional levels of activity, emotional functioning, and quality of life. The short-term goal is to assess the feasibility of multiple Clinical and Translational Research Award (CTSA) sites working together to perform and study the effects of a cognitive behavioral therapy intervention in a future randomized controlled trial (RCT) among CNCP patients in rural primary care practices in each CTSA state.

NCT ID: NCT03666299 Not yet recruiting - Chronic Pain Clinical Trials

Lidocaine Infusion for Postthoracotomy Pain Syndrome

LIPPS
Start date: September 15, 2018
Phase: N/A
Study type: Interventional

This study seeks to investigate lidocaine infusion to reduce postthoractomy pain syndrome after thoracic Surgery

NCT ID: NCT03664921 Not yet recruiting - Neuropathic Pain Clinical Trials

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Start date: October 1, 2018
Phase: Phase 2
Study type: Interventional

This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo. The order of the Omnitram and placebo treatment will be random.

NCT ID: NCT03661840 Not yet recruiting - Chronic Pain Clinical Trials

Acceptance and Commitment Therapy for Chronic Pain in Cancer Survivors

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

A study to help manage chronic pain in cancer survivors through Acceptance and Commitment Therapy (ACT) after undergoing active cancer treatment, such as surgery, chemotherapy, and/or radiation.

NCT ID: NCT03656679 Not yet recruiting - Pain, Postoperative Clinical Trials

Paravertebral Versus Pectoralis Block for Post Mastectomy Pain

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period. This study therefore aims to assess if both acute and chronic post-operative mastectomy pain can be better managed by a novel regional anesthesia nerve block known as the pectoralis block (PECs). The PECs block is easier for patients to position for placement, has less risk of harm to nearby structures, and less risk for systemic uptake of local anesthetic in comparison to the paravertebral block. The PECs block has a strong safety profile. Standard of care at University of Wisconsin (UW) hospital is to utilize regional anesthesia for post op pain management. While PVB is performed on a regular basis at UW per surgeon request, Surgeon can request for PECS block in patients where a PVB was contraindicated (ie. coagulation issues). PECS is in fact the standard of care at other hospitals. This study will assess outcomes in the post anesthetic care unit (PACU), post-operative day 1, 7 and 30.

NCT ID: NCT03655600 Not yet recruiting - Breast Cancer Clinical Trials

Acupressure for Pain and Opioid Use Among Breast Cancer Patients

AcuPOP
Start date: September 4, 2018
Phase: N/A
Study type: Interventional

This study seeks to determine the feasibility of recruiting and training participants in self-acupressure, for women undergoing primary breast cancer surgery or delayed reconstruction surgery. The study seeks to determine also if self-acupressure is effective in reducing the need for opioids post-surgery and the effects on other life factors.

NCT ID: NCT03655132 Not yet recruiting - Chronic Pain Clinical Trials

Developing an Online Therapeutic Intervention for Chronic Pain in Veterans

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

Chronic pain is a serious concern that disproportionately affects Veterans compared to the general public; Veterans are diagnosed with chronic pain at particularly high rates (47 - 56%) with a 40% greater rate of severe pain than non-Veterans. Veterans with chronic pain face numerous negative functional outcomes, including decreased ability to complete daily work activities, less social support from and closeness with family members, increased chronic health conditions (e.g., cancer, heart disease), and higher mortality compared to Veterans without chronic pain. Given these concerns, there is an urgent need for innovative and integrative approaches for non-medical pain self-management management. Despite the critical importance of effective pain self-management programs, many Veterans with chronic pain do not engage in pain self-management programs. In order to improve Veterans' quality of life, it is important to develop and evaluate innovative, accessible, evidence-based interventions for managing chronic pain. One approach with over twenty years of efficacious treatment for chronic pain is Acceptance and Commitment Therapy for Chronic Pain (ACT-CP). ACT is a well-established VA-approved approach to chronic pain management, and focuses on committing to behavior change that reflects personal values, leading to significant improvement in life functioning. ACT- CP is associated with substantial improvements in social/work functioning and decreased pain-related medical visits, as long as three years following treatment. For adults with chronic pain, technology-assisted ACT treatment leads to reduced self-reported pain levels and improved health via changes in value-aligned behaviors and mindfulness. The use of interactive technology-assisted ACT treatment is acceptable and efficacious; however, no ACT for chronic pain online treatment exists for Veterans. The investigators will thus complete a three-phase development, intervention usability and feasibility, and RCT pilot to create a virtual ACT intervention for chronic pain (VACT-CP) for Veterans. VACT-CP will utilize a personalized, social interface to address pain-related distress and functional difficulties of chronic pain (e.g., avoidance, reactivity), using an online Embodied Conversational Agent (ECA) that will walk Veterans through eight weeks of treatment. Studies suggest that the use of such ECAs can increase online-treatment motivation and feedback, resulting in increased treatment compliance and utilization, physical functioning (e.g., increased physical activity and diet fidelity), and client-goal achievement. The primary outcomes for this project will be to (1) develop the VACT-CP user system using feedback from mental health and other clinical professionals treating chronic pain (n = 10), (2) pilot the usability and feasibility of the through iterative usability development and Veteran feedback (n = 12 - 15), and (3) explore the impact of the VACT-CP system in terms of user-experience, functional outcome improvement, and quality of life measures (n = 40).

NCT ID: NCT03654235 Completed - Chronic Pain Clinical Trials

Pain Neuroscience Education and Physical Exercise Program in Chronic Back Pain

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

This study evaluates the effects of a pain neuroscience education (PNE) and physical exercise (PE) program in patients with chronic back pain. Half of participants receive PNE and PE program supervised by a physiotherapist and the other half receive usual physiotherapy care supported by physiotherapy protocols in primary care.