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Pain clinical trials

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NCT ID: NCT03374059 Completed - Pain Clinical Trials

Exercise and Life Modification for Text-Neck

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Objectives: The purpose of the study was to investigate the effects of exercise and life modification on pain and disability in "text neck". Methods: Eighty-five participants were randomly divided into three groups: Exercise (n=29), Exercise+Life modification (n=28), and Control Group (n = 28). Pain intensity during rest, activity, and at night was evaluated with Visual Analogue Scale (VAS) and functional assessment was done by using Neck Disability Index at the beginning and at the end of 4 weeks.

NCT ID: NCT03368326 Completed - Brain Injuries Clinical Trials

Use of Critical-Care Pain Observation Tool and Bispectral Index for Detection of Pain in Brain Injured Patients

Start date: June 9, 2015
Phase: N/A
Study type: Observational

Brain injured patients are at high risk of pain due to the illness itself and a variety of nociceptive procedures in intensive care unit. Since the disorder of consciousness, speech, and movement, it is usually difficult for them to self-report the presence of pain reliably. The Critical-Care Pain observation Tool (CPOT) has been recommended for clinical use in the critically ill patients when self-report pain is unavailable. Besides, it seems that the bispectral index (BIS), a quantified electroencephalogram instrument, can be used for pain assessment along with the CPOT tool in some nonverbal critical ill patients (e.g., intubated and deep sedation). However, the validity and reliability of CPOT and BIS for pain assessment in brain injured patients are still uncertain so far. So the aim of this research is to investigate the value of CPOT and BIS for pain evaluation in this specific patient group.

NCT ID: NCT03349853 Completed - Pain Clinical Trials

Description of the Use of Subcutaneous Acetaminophen in Palliative Care Unit in France: Descriptive Questionnaire Survey

EnPasc
Start date: May 18, 2016
Phase: N/A
Study type: Observational [Patient Registry]

Acetaminophen is a drug commonly used in palliative care unit, for its antalgic and antipyretic effects. Several administration routes are possible but the use of the sub-cutaneous route is actually not supported by recommandations.

NCT ID: NCT03336099 Completed - Pain Clinical Trials

Assessment of the Effect of Spa Treatment on the Functional Severity of Arthrosis

VALS
Start date: March 29, 2016
Phase: N/A
Study type: Interventional

Assessment of the effect of spa treatment on the functional severity of arthrosis. Official title: Evolution of clinical state of patients with rheumatic disease on lower limbs or rachis, 6 months after spa treatment. Primary outcome measure: - Measuring the effect of spa treatment on functional severity of arthrosis - Proportion of patients with a WOMAC score augmented by 9 or more, 6 months after enrollment (minimal clinically important difference) Secondary outcome measures - Quantitative evaluation of pain - Comparison of mean Visual Analogue Scale (VAS) pain scale between enrollment and 6 months after - Quantitative evaluation of WOMAC - Comparison of mean WOMAC between enrollment and 6 months after - Impact of spa treatment on the patient's metabolism - Height and Weight (BMI calculation) - Blood pressure - Heart rate - Quality of life - 36-Item Short Form (SF36) at enrollment, 3 months and 6 months - EuroQol 5 Dimensions (EQ5D) questionnaire at enrollment, 3 months and 6 months - Opinion of doctor and patient - Semi-quantitative scale collected at enrollment, 3 months and 6 months - Treatment follow-up - Self-evaluation of pain - Self-evaluation of pain with VAS pain scale every 6 week

NCT ID: NCT03322956 Completed - Quality of Life Clinical Trials

Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 1)

CLBP
Start date: February 9, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain. This after following an episode of 6 weeks 2 times a week physiotherapeutic back rehabilitation according to the 4 times T method by orthopedic disorder ® (4MTOR®). The results in this research will be analyzed and reported. In this study, 7 dependent variables will be independently examined relative to 2 independent variables.

NCT ID: NCT03315481 Completed - Pain Clinical Trials

Ultrasound Guided Repositioning of a New Sutureā€Method Catheter for Adductor Canal Block

Start date: March 7, 2017
Phase: N/A
Study type: Interventional

This is a randomized clinical trial in healthy volunteers. 12 volunteers will have suture-method catheters placed in the adductor canal of each leg using the long-axis plane and short-axis plane technique. The investigators will inject LA in both catheters to confirm correct position. Following return of cold sensation the catheter is then displaced intentionally. The orifice is identified by injection of isotonic saline to ensure a proper displacement (spread outside of the adductor canal) and the distance from the delivery orifice of the catheter to the adductor canal is noted. A second investigator will assess distance from the LA delivery orifice of the catheter to the adductor canal using hydrodissection with isotonic saline to pinpoint the delivery orifice and subsequently reposition the catheter to obtain LA spread within the adductor canal. Successful repositioning is defined as a combination of LA spread within the adductor canal and loss of cold sensation on the medial part of the lower leg.

NCT ID: NCT03313336 Completed - Pain Clinical Trials

A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects.

EMLA
Start date: October 30, 2017
Phase: Phase 1
Study type: Interventional

A double-blind, randomized, 2-period, placebo-controlled, single-center, crossover study, efficacy study demonstrating the therapeutic equivalence of the test cellulose disc (matrix) in EMLA patch and the current commercial cellulose disc (matrix) in EMLA patch in healthy subjects.

NCT ID: NCT03312933 Completed - Pain Clinical Trials

Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear

Start date: March 19, 2015
Phase: N/A
Study type: Interventional

This is a prospective randomized, control trial investigating ankle pain resulting from the use of CAM Walking Boots.

NCT ID: NCT03286946 Completed - Pain Clinical Trials

Detection of Intravascular Injection Between Blunt and Sharp Needles During Cervical Transforaminal Epidural Block.

Start date: October 20, 2016
Phase: N/A
Study type: Interventional

This study evaluates the incidence of intravascular injection during cervical transforaminal epidural block using blunt needle, compared to the sharp needle. The investigators will performed cervical transforaminal epidural block using blunt-type block needle in half of participants or sharp-type block needle in the other half.

NCT ID: NCT03280238 Completed - Pain Clinical Trials

Pupil Dilation and Analgesia Nociception Index

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Pain assessment is crucial in clinical practice. Currently, subjective self-report is considered the most appropriate method to evaluate pain. Although several methods to assess pain objectively exist, the lack of a golden standard still remains. This pilot study assesses the changes in pupil dilation (PD) and the analgesia nociception index (ANI) as a measure of pain in healthy, conscious, male volunteers in a highly standardized and individualized environment. Nineteen subjects received three blocks of 4 individualized electrical stimulus intensities, ranging from no to severe pain. Subjects reported their perceived severity of each individual stimulus, enabling the comparison of changes in PD and ANI in relation to both administered stimulus intensities and perceived pain severities. PD and ANI were measured before and after each administration of a stimulus.