Clinical Trials Logo

Pain clinical trials

View clinical trials related to Pain.

Filter by:
  • Recruiting  
  • Page 1 ·  Next »

NCT ID: NCT03730246 Recruiting - Pain Clinical Trials

Pain After Cesarean Sectio.

Start date: August 1, 2018
Study type: Observational

To study the strength of postoperative pain 0-24 hrs after elective cesarean sectio in spinal anaesthesia.

NCT ID: NCT03726242 Recruiting - Pain Clinical Trials

Peripheral Nociceptive Effects of Levcromakalim

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Intradermal and intramuscular injection of levcromacalim and placebo (sterile saline) on the forehead and forearm of healthy subjects and the following will be investigated: 1. Prevalence and intensity of pain 2. Prevalence and intensity of itching 3. Occurrence and intensity of local redness and swelling 4. Occurrence and intensity of local changes in skin temperature and blood flow

NCT ID: NCT03700528 Recruiting - Diabetes Mellitus Clinical Trials

The Development of Contextual Cognitive Behavioural Approach to PDN

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Diabetes mellitus (DM) is highly prevalent, and a significant public health problem. Approximately 25-30% of all individuals with DM develop painful diabetic neuropathy (PDN). PDN is considered a complex, multi-dimensional condition, possibly affecting the physical and mental health of the individual. PDN is usually described as a sense of burning, stabbing, aching and/or pricking mainly affecting areas like toes, legs, and feet and physically interfering with mobility, sleep, mood, and overall quality of life. This condition represents both a significant problem in its own right and a useful condition in which to test treatments that may offer wider benefits for neuropathic pain conditions in general. A relatively new and promising approach to chronic pain, within the wider range of cognitive and behavioural approaches, is Acceptance and Commitment Therapy (ACT). ACT is a form of Cognitive Behavioural Therapy (CBT) that focuses specifically on increasing psychological flexibility. Psychological flexibility is the capacity to change or continue with a behaviour, depending on which is more effective, according to one's goals and what the current situation affords. Psychological flexibility in turn includes processes of acceptance, values-based action, and other processes related to mindfulness. There are no published studies of ACT for individuals with PDN, and the limited available evidence indicates that a CBT-based intervention like ACT has the potential to reduce pain in people with PDN. People with PDN have clear treatment needs. While ACT may help them, little is known directly about the relevance of different components of ACT for this condition or about how to customise it for them. The proposed research aims to conduct a small feasibility trial which will pilot test a psychological treatment for PDN and assess the feasibility, acceptability and effectiveness of such a treatment.

NCT ID: NCT03700502 Recruiting - Clinical trials for Painful Diabetic Neuropathy

Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic Neuropathy

Start date: June 5, 2016
Study type: Observational

Patients with painful diabetic neuropathy (PDN) often combine with anxiety and depression. However, the pathogenesis of PDN is unclear, especially the mechanism associated with central nervous system. The investigators used fraction Amplitude of Low Frequency Fluctuation (fALFF) and Regional Homogeneity (ReHo) of resting-state functional Magnetic Resonance Imaging (rs-fMRI) to explore the brain activity in patients with PDN in order to study the central mechanism.The investigators evaluated the symptoms, signs and mental conditions of patients with PDN and non-pain neuropathy. The brain Blood Oxygen Level Dependent (BOLD) fMRI scan was performed in patients together with some gender and age matched healthy controls. Maybe this study can find that patients with PDN have abnormal brain activity, indicating central nervous system may contribute to painful diabetic neuropathy.

NCT ID: NCT03698526 Recruiting - Pain Clinical Trials

Virtual Reality for Symptoms Control in Palliative Care

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate how Virtual Reality (VR) can be used to control symptoms and improve the quality of life in palliative care. The interventional prospective case control study is planned to contain five phases including two control groups. The following describes only phase one to three. In the pilot phase patients get a one-time application of the VR-Technology. After that, two control groups will be recruited from patients with 1. mamma carcinoma and the indication of (neo-) adjuvant radiotherapy and 2. before a colonoscopy-treatment. Both groups receive the VR application before treatment (radiotherapy/colonoscopy). This first part proofs the application of Virtual Reality on patients in palliative care with the aim to control symptoms and reduce pain and anxiety. The clinical study hypothesis bases on the assumption that VR reduces pain and anxiety and may have a positive influence on their quality of life.

NCT ID: NCT03697720 Recruiting - Pain Clinical Trials

Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain

Start date: May 9, 2018
Phase: Phase 4
Study type: Interventional

The goal of this study is to see if optimized use of naproxen for treatment of dysmenorrhea will improve pain report from baseline. In addition, we will determine whether cross-organ influences from the uterus on bladder pain sensitivity change from baseline after reduced menstrual pain experience over six months. Finally, a battery of quantitative sensory tests and EEG measures of sensory sensitivity will be used to evaluate mechanisms associated with improvements in menstrual and bladder pain.

NCT ID: NCT03689205 Recruiting - Pain Clinical Trials

The Effect of Obesity on Venous Puncture Pain

Start date: June 20, 2018
Study type: Observational

Before surgery, patients will fill the Beck anxiety, distress tolerance test and Pain katastrophizing test. Patients will be divided into two groups according to BMI> 30kg / m2 (Group A) and BMI <30kg / m2 (Group B). Compared to body weight, venous vascular pain of the groups will be compared.

NCT ID: NCT03678662 Recruiting - Pain Clinical Trials

Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.

Start date: September 19, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate how expectations induced by information given prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min wallsquat exercise in healthy subjects. The study is a double blinded (participant, investigator) randomized controlled trial The results from the study may be of great importance to the understanding of exercise-induced hypoalgesia, and whether the information related to exercise as pain relief can be used in practice for patients with pain. The subjects are randomized to 1 in 3 groups. Hypoalgesia expectation, hyperalgesia expectation, neutral expectation. Each group (besides the neutral group) is given different information of what to expect on pain ratings after a 3 minutes wallsquat.

NCT ID: NCT03670420 Recruiting - Pain Clinical Trials

The Application of Honey on Perineal Sutures

Start date: September 10, 2018
Phase: N/A
Study type: Interventional

Evaluate the effect of honey on perineal tears or episiotomies pain associated or not with anterior vulvar tears after vaginal delivery.

NCT ID: NCT03665753 Recruiting - Pain Clinical Trials

Comparison of IV 10, 20, and 30mg for Renal Colic Pain in the ED

Start date: August 5, 2017
Phase: Early Phase 1
Study type: Interventional

Hypothesis: Intravenous administration of Ketorolac 10 mg and 20 mg is as effective as 30 mg in treating renal colic pain in patients presenting to the emergency department