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Pain clinical trials

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NCT ID: NCT03628989 Not yet recruiting - Pain Clinical Trials

Technology-Based Distractions During Minor Procedures

Start date: August 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset, Augmented Reality Headset) are more effective than the standard of care (i.e., no technology-based distraction) for decreasing anxiety and pain scores in pediatric patients undergoing various minor procedures (i.e lumbar punctures and cardiac catheterization). The anticipated primary outcome will be a reduction of overall cumulative medication and secondary outcomes include but are not limited to: physician satisfaction, discharge time, pain scores, anxiety scores, and procedure time.

NCT ID: NCT03628547 Not yet recruiting - Pain Clinical Trials

Assessment of Musculoskeletal Pain and Psychosocial Status of Athletes

Start date: August 15, 2018
Study type: Observational

The sporty performance exhibited by an athlete faces physiological, biomechanical and psychological activity of the athlete. It depends on both the psychological state and the elevation of the musculoskeletal system to a certain level so that the athlete can perform optimally and excellently. For this reason, we aimed to evaluate the musculoskeletal system pain of amateur and professional athletes in different disciplines and the psychosocial states such as sports confidence, depression and quality of life.

NCT ID: NCT03628430 Completed - Pain Clinical Trials

Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Subcutaneous implantable venous access devices are routinely implanted under local anesthesia. However, patients complain of pain during the injection of local anesthesia. The aim of this study was to evaluate the effectiveness of sodium bicarbonate-buffered lidocaine with epinephrine on reducing pain and patients' satisfaction during subcutaneous implantable venous access devices insertion. A prospective double-blind study was conducted over a period of 6 months (1st January 2017 to 30th June 2017). Patients were randomized to receive either buffered (PH= 7.33) or plane lidocaine (PH= 3.50). The same operator made all insertions using a standard technique. Pain at five procedural steps (local anesthetic infiltration, central vein cannulation, skin incision, deep tissue dissection and pocket formation, and skin closure) and satisfaction were evaluated on a VAS score (0-100 mm). Secondary outcomes were sensory block onset time using pinprick test and patients' satisfaction.

NCT ID: NCT03618875 Completed - Pain Clinical Trials

Reduction of Post Intravitreal Injection Bleeding and Pain by Ice

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Intravitreal injections are an efficient method for delivering intraocular therapeutic agents in numerous ophthalmologic diseases. However, side effects, such as pain and subconjunctival hemorrhage remain a major concern. Prevention or alleviation of those side effects might shorten the healing duration and improve patients' quality of life.

NCT ID: NCT03618693 Recruiting - Pain Clinical Trials

Impact of Perioperative Analgesia in Prostatectomy Patients on Early Quality of Recovery (SPITALIDO)

Start date: August 13, 2018
Phase: N/A
Study type: Interventional

The rationale behind this RCT is to assess within 24 hours after surgery the quality of recovery of prostatectomy patients treated with 3 different analgesia concepts (intraoperative spinal analgesia, transversus abdominis plane block, intravenous lidocaine administration) using the quality of recovery (QoR) 15 questionnaire.

NCT ID: NCT03617510 Recruiting - Pain Clinical Trials

A Phase I Clinical Study Trial of Felbinac Trometamol Injection in China

Start date: July 20, 2018
Phase: Phase 1
Study type: Interventional

1. To evaluate the tolerances of healthy subjects treated with Felbinac Trometamol Injection on multiple dose and single dose 2. To evaluate the pharmacokinetic characteristics in healthy subjects treated with Felbinac Trometamol Injection on multiple dose and single dose 3. To provide the basis for the dose for the follow-up clinical study.

NCT ID: NCT03617471 Active, not recruiting - Pain Clinical Trials

Pharmacokinetic Study of Paracetamol in Patients Over 80 Years Hospitalized to an Acute Geriatric Ward

Start date: November 2015
Phase: N/A
Study type: Interventional

The goal of this exploratory study is the characterization of the pharmacokinetic profile of paracetamol in older patients and the specific PK variables associated with plasma exposure in this population.

NCT ID: NCT03616639 Recruiting - Pain Clinical Trials

Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function

Start date: June 4, 2018
Phase: Phase 4
Study type: Interventional

Significant pain is a common condition in dying patients. Continuous subcutaneous infusion (CSCI) of opioids is the cornerstone in treatment of pain in this last phase of life. Although morphine is the most frequent used opioid in this respect, burdensome adverse effects, like delirium and allodynia/hyperalgesia, can occur in dying patients, due to accumulation of morphine metabolites in decreasing renal function. Oxycodone seems preferable in this situation, as central effects of circulating metabolites of oxycodone are negligible. However, studies of sufficient quality investigating the clinical effect of this hypothesis are lacking at the moment. This study investigates whether there is a difference in occurrence of delirium and allodynia/hyperalgesia between oxycodone and morphine. Residents of hospices and somatic or psychogeriatric (PG) wards of nursing homes in the Netherlands, who are eligible for start of CSCI of an opioid for the treatment of pain in the terminal phase of life, are randomly assigned to one of two groups. One group receives CSCI of oxycodone and the other group CSCI of morphine. 117 patients per group are needed. Occurrence of delirium and allodynia/hyperalgesia is assessed three times a week until death of the participant. Quality of dying, as perceived by the patient's relatives, is assessed in an interview with a relative after death.

NCT ID: NCT03613155 Not yet recruiting - Pain Clinical Trials

Assessment of Anxiety in Patients Treated by SMUR Toulouse and Receiving MEOPA as Part of Their Care

Start date: September 2018
Study type: Observational

The emergency setting, frequently associated with pain and the feeling of loss of control, can cause anxiety in patients. Reaction anxiety may be an appropriate response to an emergency; Nevertheless, attention must be paid to the evaluation and management of the latter especially as anxiety and pain are closely linked.

NCT ID: NCT03610503 Not yet recruiting - Pain Clinical Trials

The Effect of Preferred Music on EMG Anxiety and Pain

Start date: July 2018
Phase: N/A
Study type: Interventional

Patients often report anxiety and pain related to electromyography (EMG) and nerve conduction studies (NCS) which are tests used to look for diseases of the nerves and muscles. Unfortunately, for those with very high levels of test related stress, the experience may be very frightening and may impede completion of the study and negatively impact on making a timely and accurate diagnosis. Several studies have shown that music can improve anxiety and pain levels in various situations and procedures. Our study will allow participants to play music of their choice during EMG and NCS in order to determine if the pain and anxiety that they experience is reduced.