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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03735719 Active, not recruiting - Heart Failure Clinical Trials

Biomarkers for Risk Stratification After STEMI

Start date: April 2014
Phase:
Study type: Observational

Despite modern reperfusion strategies, myocardial infarction leads to deleterious processes resulting in left ventricular remodelling (LVR) and heart failure (HF). Several biomarkers i.e. galectin-3 (Gal-3) and soluble ST-2 protein are involved in LVR as a result of inflammatory processes and fibrosis. There is an evidence of a high prognostic value of both biomarkers in prediction of outcomes in HF patients. This study will further investigate the role of Gal-3 and ST-2 in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) and without prior HF in prediction of unfavourable outcomes.

NCT ID: NCT03733665 Active, not recruiting - Heart Failure Clinical Trials

HES and NICOR Data Linkage for Cardiac Failure Population Analysis

Start date: November 6, 2018
Phase:
Study type: Observational [Patient Registry]

This study is a population-based, patient-level analysis of heart failure in England over a 5-year period using a dataset created by linking HES and NICOR databases. Our analyses will look into the re-occurrence of hospitalisation after the initial diagnosis of heart failure, the influence of population factors on risk of re-hospitalisation, and the resultant cost implications in an NHS environment.

NCT ID: NCT03714126 Active, not recruiting - Heart Failure Clinical Trials

Mobile Phone Health Application Assessment in Subjects With Heart Failure

Start date: November 5, 2015
Phase:
Study type: Observational

This is an observational, non-interventional, prospective, single-arm, open study for database establishment for R&D purposes. The study will be conducted in 1 site in Israel with up to one hundred (100) patients. Patients under hemodialysis supervision will be enrolled in the clinical trial. Clinical information for the study will be collected at the hospital and at home. The patient will conduct recordings at home every day.

NCT ID: NCT03701880 Active, not recruiting - Clinical trials for Heart Failure With Reduced Ejection Fraction

Early Use of Ivabradine in Heart Failure

Ivabradine
Start date: September 16, 2018
Phase: N/A
Study type: Interventional

The aim of the work is to Evaluate the efficacy, quality of life and safety of early addition of ivabradine to B-blocker in reduced EF heart failure patients after acute decompensation compared to the standard treatment.

NCT ID: NCT03661060 Active, not recruiting - Heart Failure Clinical Trials

BLITZ Heart Failure

BLITZ-HF
Start date: March 8, 2017
Phase:
Study type: Observational [Patient Registry]

To evaluate if Italian Cardiologists are treating Heart Failure (HF) patients according to International guidelines and if a structured educational program can improved their adherence.

NCT ID: NCT03611153 Active, not recruiting - Heart Failure Clinical Trials

MPO Inhibitor A_Zeneca for HFpEF

Start date: July 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The researchers want to find out more about the effect of a single dose of oral myeloperoxidase on heart failure versus placebo.

NCT ID: NCT03566264 Active, not recruiting - Clinical trials for Heart Decompensation

Study of the Sudden Heart Failure Participant Population in the US

Start date: August 22, 2017
Phase:
Study type: Observational

An observational study using data from a large US electronic health record database to find participants hospitalized with ADHF who do not have a concurring heart attack

NCT ID: NCT03549169 Active, not recruiting - Heart Failure Clinical Trials

Decision Making for the Management the Symptoms in Adults of Heart Failure

TOMAS
Start date: September 4, 2017
Phase: N/A
Study type: Interventional

Introduction. Heart failure (HF) is the most prevailing chronic illness in the world. In Colombia, high morbidity and mortality rates because of HF are registered, as well as a significant burden of symptoms, frequent hospitalizations, poor quality of life, significant consumption of health resources and early mortality. It is necessary to propose novel strategies that can change the current picture. Objective: determine the efficacy of an intervention centered in decision taking for the handling of symptoms in adults with HF who live in the department of Cordoba, Colombia. Hypothesis Primary hypothesis: the intervention Decision taking for the handling of symptoms in adults with HF: 1) Increases self-care. Secondary hypothesis: 1) reduces clinical events: emergency care and hospitalizations, 3) Improves quality of life related to health.

NCT ID: NCT03535909 Active, not recruiting - Clinical trials for Congestive Heart Failure

Hemodynamic Assessment in Acute Decompensated Heart Failure

Start date: June 9, 2018
Phase:
Study type: Observational

This study will assess the ability of a novel optical measurement system to determine changes in the hemodynamic status of heart failure patients admitted to the hospital with a primary diagnosis of acute decompensated heart failure. Patients will be measured with both the novel measurement system and reference devices that are FDA-cleared for hemodynamic measurements. The measurements from the novel system will be compared to reference variables describing hemodynamic and congestive status, including stroke volume, central venous pressure, and serum levels of NT-proBNP.

NCT ID: NCT03524534 Active, not recruiting - Heart Failure Clinical Trials

The Heart Failure Readmission Intervention by Variable Early Follow-up (THRIVE) Study

THRIVE
Start date: January 2017
Phase: N/A
Study type: Interventional

This study is a pragmatic randomized clinical trial to determine the effectiveness of two strategies of early follow-up in adults after hospitalization for heart failure: telephone follow-up with a heart failure care manager vs. in-person clinic visit with their primary care provider. The primary outcomes during 30-day follow-up will include readmission for heart failure, death and readmission for any cause. The study team will randomly assign 2400 patients during a 15-month period in a 1-to-1 ratio to either an initial structured telephone call with a heart failure care manager or an in-person primary care clinic visit within 7 days of discharge. A secondary goal is to increase the rate of any follow-up within 7 days of discharge to greater than 90 percent among all eligible patients.