Clinical Trials Logo

Chronic Heart Failure clinical trials

View clinical trials related to Chronic Heart Failure.

Filter by:

NCT ID: NCT03494933 Not yet recruiting - Clinical trials for Chronic Heart Failure

Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

RESET-CRT
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

NCT ID: NCT03474315 Not yet recruiting - Clinical trials for Chronic Heart Failure

Interactive Patient's Assistant - LUCY

Start date: April 2018
Phase:
Study type: Observational [Patient Registry]

Patients with chronic heart failure (CHF) and reduced left ventricle ejection fraction benefit from cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillator (ICD). Currently used devices, besides delivering low and high-energy therapies, record patient's activity and many hemodynamic parameters. However, increasing numbers of patient with CRT and ICD devices produce overload of cardiology centers where patients are admitted to ambulatory visits. Contrarily, there are technological possibilities for remote monitoring proven to be effective in recognizing damage of the implanted device and risk of exacerbation of chronic heart failure. Patients' registries show that majority of ambulatory visits are unproductive and do not result in significant modification of device's parameters. Promising experiences with application of data mining and machine learning techniques allow us to assume probable benefits from using modern methods of data analysis in determination of requirement for ambulatory follow-up on basis of data gathered through telemonitoring and clinical assessment of a patient. Aim of the study is to find multivariate model predicting the requirement for ambulatory follow-up of IECD.

NCT ID: NCT03416361 Not yet recruiting - Clinical trials for Chronic Heart Failure

VItamiN D treatIng Chronic heArT Failure (the Effect of Vitamin D Supplementation in Patients With Heart Failure)

VINDICATE2
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

VINDICATE 2 will be a randomised, placebo-controlled, parallel group, double-blind study of vitamin D versus placebo in otherwise optimally-managed patients with CHF due to LVSD and vitamin D deficiency (<50nmol/L). The intervention will be a daily dose of 4000IU (100µg) per day or matching placebo for a minimum of 2 years and a maximum of 4 years.

NCT ID: NCT03388593 Not yet recruiting - Clinical trials for Chronic Heart Failure

Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients

Start date: February 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate efficacy of rhNRG-1 in reducing the death rate of heart failure subjects with baseline NT-proBNP level <1600 pg/mL and NYHA class II to III.

NCT ID: NCT03351400 Recruiting - Clinical trials for Chronic Heart Failure

Japanese OMI Treatment With Kit-positive Cells for Enhanced Regeneration

JOKER
Start date: November 15, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of intracoronary infusion of autologous cardiac stem cells in patients with ischemic cardiomyopathy.

NCT ID: NCT03344523 Not yet recruiting - Clinical trials for Chronic Heart Failure

Evaluating Iron Protein Succinylate Oral Solution in Treating Chronic Heart Failure and Iron Deficiency

Start date: January 2018
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the effect of standard heart failure therapy plus oral solution with protein succinylate iron compared to placebo on the primary end point of 6 minute walk distance at 24th week in patients with chronic ejection fraction reduction heart failure and iron deficiency.

NCT ID: NCT03342833 Not yet recruiting - Clinical trials for Chronic Heart Failure

Blood Flow Restriction Training in Chronic Heart Failure: an Effective Training Strategy?

BFR-CHF
Start date: January 2018
Phase: Phase 2
Study type: Interventional

The purpose of this current study proposal is to identify the potential physiological adaptations arising from a combined BFR+HIIT training intervention in CHF patients. We hypothesise that the addition of BFR to HIIT will increase whole-body V̇O2peak by promoting vascular and skeletal muscle adaptations above that seen with HIIT alone. The secondary outcomes of this study are to determine if such a training intervention leads to clinical improvements in exercise intolerance symptoms and quality of life indices. Given that the majority of previous research in to both BFR and HIIT has largely involved young, healthy and relatively active participants, the final objective of this current proposal is to determine the viability, tolerability and efficacy of these training modalities in an elderly cohort of predominantly sedentary CHF patients.

NCT ID: NCT03342690 Recruiting - Clinical trials for Chronic Heart Failure

Drug Use Investigation of Selara Tablets (an Investigation for Chronic Heart Failure)

Start date: July 5, 2017
Phase: N/A
Study type: Observational

Secondary Data Collection Study; Safety And Effectiveness Of Selara Under Japanese Medical Practice

NCT ID: NCT03333499 Recruiting - Clinical trials for Chronic Heart Failure

the Effects of YangXinShi (YXS) on the Quality of Life and Exercise Tolerance in Patients With Chronic Heart Failure

Start date: November 1, 2017
Phase: Phase 1
Study type: Interventional

The investigators set out to evaluate the effects of the traditional Chinese medicinal mixture under the brand name YangXinShi (YXS) on the prognosis in patients with chronic heart failure when it is combined with the optimal combination drug treatment of heart failure.

NCT ID: NCT03320655 Active, not recruiting - Clinical trials for Chronic Heart Failure

Effectiveness of Combined Aerobic and Strength Training in Acute and Chronic Adaptations in Patients With Heart Failure

Start date: October 9, 2017
Phase: N/A
Study type: Interventional

Patients with chronic heart failure (CHF) underwent to a hospital-based cardiac rehabilitation (CR) program in the Lisbon district Hospitals will be recruited. The participants will be randomized into one of the following exercise groups: A) combined exercise training with more aerobic training and less strength training (CAT); B) combined exercise training with more strength training and less aerobic training (CST). The investigators will test two proportions in combined training, CAT and CST. There hasn't been any data on the so called combined regimes, which include both aerobic exercise with HIIT and ST and the investigators will evaluate the effects of acute and chronic response. The research project will contribute to a better understanding in several aspects that are unexplained by scientific research.