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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03671122 Recruiting - Clinical trials for Heart Failure, Diastolic

PREFERS (Preserved and Reduced Ejection Fraction Epidemiological Regional Study) Stockholm Heart Failure Study

Start date: January 1, 2015
Study type: Observational

Heart failure (HF) with preserved (HFpEF) or reduced (HFrEF) ejection fraction is associated with poor prognosis and quality of life. While the incidence of HFrEF is declining and HF treatment is effective, HFpEF is increasing, with no established therapy. PREFERS Stockholm is an epidemiological study with the aim of improving clinical care and research in HF and to find new targets for drug treatment in HFpEF starting with a cardiac biopsy study in elective CABG patiens.

NCT ID: NCT03667989 Recruiting - Clinical trials for Chronic Heart Failure

SPECT-based Prediction and Evaluation of CRT Efficacy in CHF

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study evaluates the state of the cardiac sympathetic activity and the severity of ventricular dyssynchrony in chronic heart failure patients and assesses the capabilities of radionuclide indication methods in determining the prognosis and evaluating the results of cardiac resynchronization therapy in chronic heart failure patients.

NCT ID: NCT03663907 Recruiting - Heart Failure Clinical Trials

Heart Failure Events Reduction With Remote Monitoring and eHealth Support Investigator Initiated Trial

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

The primary objective of the study is to evaluate the efficacy of a telemedicine-based follow-up strategy compared with usual care in the management of patients with chronic heart failure (HF) at high risk of clinical events.

NCT ID: NCT03659877 Recruiting - Heart Failure Clinical Trials

Identifying Physical Activity Intensity Through Accelerometry in Heart Failure

Start date: April 3, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to identify and evaluate the range of values provided by accelerometers during a variety of typical daily lifestyle activities for heart failure patients, and to relate these to the measured intensity of performing each activity in the heart failure population.

NCT ID: NCT03658174 Recruiting - Heart Failure Clinical Trials

Upregulating the Nitric Oxide Pathway To Restore Autonomic Phenotype (UNTRAP).

Start date: August 31, 2018
Phase: N/A
Study type: Interventional

Autonomic nervous system dysfunction is known to be associated with an increased risk of heart rhythm abnormalities and sudden cardiac death (SCD) in patients with chronic heart failure - a condition affecting millions of people worldwide. The nitric oxide pathway has been identified as being involved in mediating the effects of the autonomic nervous system on the heart. Recent studies have shown that dietary nitrates can increase the availability of nitric oxide in the body. This study hopes to find out if dietary nitrate supplementation can help to improve cardiac and autonomic function in patients with heart failure and autonomic dysfunction and reduce the risk of arrhythmias.

NCT ID: NCT03657459 Recruiting - Clinical trials for Heart Failure; With Decompensation

Danger Signs in Heart Failure- Effects of Video Education

Start date: July 26, 2018
Phase: N/A
Study type: Interventional

Lack of recognition of HF danger signs and lack of understanding of how to control and minimize danger signs could lead to their escalation and prompt all-cause and HF-related health care resource utilization (HCRU). Investigators hypothesize that patients must understand HF danger signs to have self-confidence in recognizing them and in taking steps to minimize or eliminate their occurrence post hospital discharge. Investigators will determine if video education in HF danger signs recognition and control prior to discharge (and post-discharge) reduces all-cause and HF-related HCRU.

NCT ID: NCT03656354 Recruiting - Heart Failure Clinical Trials

Identification of Heart Failure Patients by Seismocardiography

Start date: June 29, 2018
Study type: Observational

The aim of the current study is to develop and validate an algorithm based on seismocardiography recordings to detect heart failure. Echocardiography will be used as the golden standard for defining patients with heart failure.

NCT ID: NCT03655925 Recruiting - Clinical trials for Chronic Heart Failure

Human Leucocyte Antigen G and Chronic Heart Failure

Start date: October 11, 2017
Study type: Observational

The Human leukocyte antigen G (HLA-G) is a non-classical, major histocompatibility complex class I (MHC-I) protein that modulates the immune response, inhibiting it in most cases. Physiologically expressed in the cells of some tissues, it increases in inflammatory reactions. Inflammation appears to play an important role in the development of chronic heart failure. This study aims to evaluate the levels of soluble HLA-G in patients with heart failure and to investigate the relationships between HLA-G and other clinical-functional parameters of the disease. Investigators hypothesize that the plasma levels of HLA-G could correlate with the clinical status of heart failure and could provide indications on patient's prognosis.

NCT ID: NCT03648762 Recruiting - Heart Failure Clinical Trials

Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit

Start date: May 8, 2017
Phase: N/A
Study type: Interventional

The purpose of this research study is to better understand how skeletal muscle is affected by heart failure, and to determine how exercise interventions impact skeletal muscle and functional capacity. While many think of heart failure as a disease that only affects the heart, doctors now believe that it actually affects the whole body, including skeletal muscle, such as the muscles of your arms and legs. Therefore, while many people with heart failure develop weakness and reduced exercise capacity, this may be related more to their skeletal muscle than their weakened hearts. This study looks directly at how exercise might change skeletal muscle and possibly improve quality of life in heart failure patients. As part of the study participants will take part in a cardiopulmonary exercise test, lower body strength testing, breathing assessment, a muscle biopsy (optional), blood draw, and DXA scanning (to assess lean body mass). Participants with heart failure will complete 1 of 3 exercise training interventions (aerobic vs. aerobic and strength vs. inspiratory) for 12 weeks and will be assessed pre and post to determine if any differences occur in their skeletal muscle and functional capacity as part of the exercise intervention.

NCT ID: NCT03644446 Recruiting - Clinical trials for Heart Failure With Reduced Ejection Fraction

Bisoprolol Plasma Residual Concentrations in Chronic Heart Failure

Start date: November 2, 2017
Study type: Observational [Patient Registry]

This study evaluate the dosage of bisoprolol plasma residual concentrations in chronic heart failure with mild to reduced ejection fraction adult patients by dose and renal function.