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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03247829 Not yet recruiting - Heart Failure Clinical Trials

Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™

Intellect2
Start date: August 15, 2017
Phase: N/A
Study type: Observational

This observational post market study is intended to characterize hemodynamic-guided management of patients with an existing left ventricular assist device (LVAD) to protocol specified target ranges and its impact on functional status, quality of life, and readmissions

NCT ID: NCT03246035 Not yet recruiting - Heart Failure Clinical Trials

Reducing Readmission for Frail Elderly Patients With Decompensated Heart Failure

HFF-ED
Start date: August 2017
Phase: N/A
Study type: Interventional

A randomized study designed to determine whether telephone based interventions can prevent return hospital visits for elderly and frail patients with acute symptoms of heart failure. Specifically, the intervention will improve patients ability to monitor and address self care of heart failure at home.

NCT ID: NCT03245281 Not yet recruiting - Heart Failure Clinical Trials

LINQ for impEdance meAsuremeNt While Off From HF Medication Study

LEAN HF
Start date: September 2017
Phase: Phase 4
Study type: Interventional

The purpose of this non-randomized, cross-over, unblinded, single-center feasibility study is to assess the sensitivity of the LINQ ICM to measure derived-subcutaneous impedance in patients with heart failure during periods when diuretics and/or HF-medication consumption is increased or suspended for 48 hours (up to 72 hours at physician discretion) and to collect safety information related to HF status and to medication consumption changes.

NCT ID: NCT03240237 Not yet recruiting - Clinical trials for Heart Failure, Diastolic

CCM in Heart Failure With Preserved Ejection Fraction

Start date: August 15, 2017
Phase: N/A
Study type: Interventional

This pilot study will evaluate the efficacy and safety of CCM therapy in heart failure patients with baseline EF≥50% (HFpEF) who have New York Heart Association (NYHA) Class II or III symptoms despite appropriate medication. The terminology of the HF classification HFpEF is based on the 2016 European Society of Cardiology (ESC) Heart Failure Guidelines.

NCT ID: NCT03238937 Not yet recruiting - Heart Failure Clinical Trials

Phrenic Nerve Stimulation for Treatment of Central Sleep Apnea

STIMULATE-CSA
Start date: August 10, 2017
Phase: N/A
Study type: Interventional

The study objectives are to demonstrate the ease and safety of bilateral cervically implanted phrenic nerve stimulators for Central Sleep Apnea in patients with Heart Failure. To demonstrate the efficacy, both in the short and long term, of implanted phrenic nerve stimulators in patients with Central Sleep Apnea and Heart Failure. Central Sleep Apnea is a form of hypoventilation syndrome, for which this device is FDA approved. We will also determine if the patient's quality and duration of life is improved by using the PNS to treat CSA in heart failure patients.

NCT ID: NCT03238729 Not yet recruiting - Heart Failure Clinical Trials

Proof-of-Concept Study of Heart Habits Application for Patients With Heart Failure

Start date: August 2017
Phase: N/A
Study type: Interventional

This study assesses the ability of ambulatory patients with heart failure (HF) to use a smartphone application created for the management of patients with chronic HF. This study will aim: - To understand the frequency with which ambulatory HF patients engage with this smartphone application. - To determine whether patient's knowledge of HF and its management has improved with the use of this smartphone application. - To assess improvement in quality of life measures related to the use of this smartphone application. - To assess improvement in lifestyle measures related to the use of this smartphone application.

NCT ID: NCT03237858 Not yet recruiting - Clinical trials for Heart Failure, Congestive

Multiple Cardiac Sensors for the Management of Heart Failure

MANAGE-HF
Start date: September 2017
Phase: N/A
Study type: Interventional

The MANAGE-HF study is a multi-center, global, prospective, open label, multi-phase trial intended to evaluate the clinical efficacy of the HeartLogic heart failure diagnostic feature.

NCT ID: NCT03234647 Not yet recruiting - Acute Heart Failure Clinical Trials

First In Human Study of the Doraya Catheter for the Treatment of AHF Patients

Start date: November 2017
Phase: N/A
Study type: Interventional

Safety and performance evaluation of the Doraya catheter in patients admitted with AHF.

NCT ID: NCT03228381 Not yet recruiting - Heart Failure Clinical Trials

The BOSS Study: An Acute Evaluation of Anatomical and Geometric Changes Using the Bladder on a Stick System (BOSS)

BOSS
Start date: July 31, 2017
Phase: N/A
Study type: Interventional

The objective of the BOSS Study is to assess acute anatomical and geometric annular and ventricular changes that occur when strategically positioned an external inflatable chambers are applied to the outside of the heart.

NCT ID: NCT03228030 Not yet recruiting - Heart Failure Clinical Trials

Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial

THIAMINE-HF
Start date: September 2017
Phase: Phase 3
Study type: Interventional

Heart failure (HF) is a major cardiovascular disease with increasing prevalence. Thiamine deficiency is common in HF patients. Previous small studies have shown that thiamine supplementation can improve left ventricular systolic function in HF, but larger clinical studies are lacking. Given the ease of supplementation and the potential benefits in HF, we aim to conduct a pilot randomized controlled trial (RCT) using high dose thiamine supplementation in HF patients. The main goal of this pilot study is to determine the feasibility of recruitment for an RCT of thiamine supplementation.