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Heart Failure clinical trials

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NCT ID: NCT03296280 Enrolling by invitation - Heart Failure Clinical Trials

Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program

Start date: October 3, 2016
Phase: N/A
Study type: Observational

This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers; and the barriers/facilitators to POCUS in the VHA. Data sources include pre- and post-course assessment tools, medical coding data, and course evaluations. Providers that participate in the POCUS Training Course will be compared to control providers from wait-listed facilities. Additionally, participating facilities vs. wait-listed facilities for the POCUS Training Course will be compared. Findings from this project will guide ongoing efforts of the investigators' operating partners, VA Specialty Care Centers of Innovation (SCCI) and the VA Simulation Learning and Research Network (SimLEARN), to develop a national POCUS training program and facilitate implementation of POCUS use system-wide in the VA healthcare system.

NCT ID: NCT03200990 Enrolling by invitation - Clinical trials for Coronary Artery Disease

PULsecath mechanicaL Support Evaluation

PULSE
Start date: December 2016
Phase: N/A
Study type: Interventional

The objective of this study is to determine ventricular loading conditions during and after PulseCath® iVAC2L support, and assess its impact on specific load dependent humoral factors and cardiac enzymes. These specific patterns are so far unknown and will be compared with the validated FDA-cleared and CE marked Impella CP. Ten cases with Impella CP will be performed in this study to obtain the exact same measurements for comparing purposes.

NCT ID: NCT03099655 Enrolling by invitation - Heart Failure Clinical Trials

Attain Stability™ Quad Clinical Study

Start date: July 7, 2017
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to evaluate the safety and efficacy of the Attain Stability Quadripolar MRI SureScan Left Ventricular (LV) lead (Model 4798).

NCT ID: NCT03078374 Enrolling by invitation - Heart Failure Clinical Trials

MAGENTUM 1 HeartMate 3 LVAS: A Single Center Prospective Controlled Study (MAGENTUM 1)

Start date: January 11, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain single-center safety and feasibility data on patients managed with reduced anti-coagulation, and the incidence of thrombotic and bleeding adverse events associated with the HeartMate 3 LVAS therapy.

NCT ID: NCT03073005 Enrolling by invitation - Heart Failure Clinical Trials

Use of Simulation to Improve VAD Self-management

Sim VAD
Start date: June 1, 2017
Phase: N/A
Study type: Interventional

This study will evaluate the performance of a curriculum using medical simulators to train patients with advanced heart failure and their caregivers to master the self-management of ventricular assist devices (a device implanted into the heart to help circulate the blood). The investigators expect this training will improve self-management skills, and reduce VAD-related infections and re-hospitalizations. In addition to providing innovative training to the patients and their caregivers, the study will advance our knowledge of the effects of simulation-based training on patient self-management and safety.

NCT ID: NCT03063697 Enrolling by invitation - Clinical trials for Congestive Heart Failure

Observational Study to Evaluate the Safety of DILATREND SR Cap. in Korean Patients With Essential Hypertension, Chronic Stable Angina and Congestive Heart Failure

DELIGHT
Start date: November 2015
Phase: N/A
Study type: Observational

The purpose of this study is to Evaluate the Safety of DILATREND SR Cap. in Korean Patients with Essential hypertension, Chronic stable angina and Congestive heart failure for 52 weeks.

NCT ID: NCT03056651 Enrolling by invitation - Heart Failure Clinical Trials

Day-care Unit for Patients With Refractory Heart Failure

DayCare-HF
Start date: April 2016
Phase: N/A
Study type: Interventional

The Day-Care Unit for Patients With Refractory Heart Failure (DayCare-HF) is an observational study on selected patients with advanced refractory heart failure. The purpose of the study was to examine the comprehensive management of HF in the day-care unit in terms of the safety and its impact on the rehospitalization and mortality rates in patients with advanced refractory HF.

NCT ID: NCT03032627 Enrolling by invitation - Heart Failure Clinical Trials

Identifying Targets of Maladaptive Metabolic Responses in Heart Failure

Start date: December 2016
Phase: N/A
Study type: Interventional

The purpose of the research is to help researchers understand changes in metabolism in patients that develop heart failure.

NCT ID: NCT03027960 Enrolling by invitation - Heart Failure Clinical Trials

Empagliflozin in Heart Failure: Diuretic and Cardio-Renal Effects

EMPA
Start date: June 27, 2017
Phase: Phase 2
Study type: Interventional

The investigators propose a small pilot proof of concept study to not only prove the existence of, but also probe the mechanisms underlying cardio-renal effects of empagliflozin in patients with heart failure. The investigators propose a 50 patient randomized, double-blind, placebo-controlled crossover study with patients with stable HF, type II diabetes and an eGFR >45ml/min/1.73 m2 who are chronically receiving loop diuretics.

NCT ID: NCT03019653 Enrolling by invitation - Heart Failure Clinical Trials

Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome

ANX-042 Aim 1
Start date: January 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to look at kidney function and hormonal function in patients with a history of heart failure and kidney dysfunction, and to see how the use of a new drug, ANX-042, affects those functions.