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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03704220 Enrolling by invitation - Heart Failure Clinical Trials

Anti-thrombotic Monotherapy With the HeartMate 3 LVAS

Start date: August 16, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain a single-center safety and feasibility data on patients managed with a single anti-thrombotic therapy and the incidence of thrombotic adverse events associated with HeartMate 3 LVAS therapy.

NCT ID: NCT03642730 Enrolling by invitation - Heart Failure Clinical Trials

Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging

EPISODE
Start date: December 1, 2017
Phase: N/A
Study type: Interventional

This prospective study is a pilot study for evaluating a guidance system that aims to facilitate high-quality echocardiographic acquisitions.

NCT ID: NCT03592355 Enrolling by invitation - Hypertension Clinical Trials

Virtual Visits at Brigham and Women's Hospital

Start date: April 13, 2018
Phase: N/A
Study type: Interventional

Clinicians slated for virtual visit rollout will be randomized (stratified by department) to either receive immediate virtual visit on-boarding (intervention arm) or delayed (3-months later) virtual visit on-boarding (control arm). The investigators plan to enroll no more than 200 clinicians. Any clinician in a department selected by the Brigham Health Virtual Care team for access to virtual visits is eligible, unless s/he saw less than 20 patients monthly over the last 6 months. The Brigham Health Virtual Care team will onboard all clinicians and provide virtual visit support as per their usual protocol. The primary study endpoint is third-available appointment, a well-adopted measure of access. Other secondary endpoints revolve around continuity, efficiency, utilization, safety, cost, and patient experience.

NCT ID: NCT03574857 Enrolling by invitation - Heart Failure Clinical Trials

Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic Resistance

Start date: June 2018
Phase: Phase 4
Study type: Interventional

The primary objective of the study is to compare efficacy of metolazone and chlorothiazide as add-on therapy in patients refractory to loop diuretics with heart failure with a reduced ejection fraction (HFrEF). This will be a single-center randomized pilot study.

NCT ID: NCT03508505 Enrolling by invitation - Cardiac Surgery Clinical Trials

Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation

PC-ECMO
Start date: January 1, 2018
Phase:
Study type: Observational

Cardiac surgery can be not infrequently complicated by cardiac low-output syndrome due to critical preoperative conditions such as cardiogenic shock, poor left ventricular function and severe myocardial ischemia. Suboptimal myocardial protection, technical errors at graft anastomoses or of prosthesis implantation, and hibernating myocardium may further contribute to cardiac low-output syndrome occurring immediately or shortly after cardiac surgery. In this setting, veno-arterial extracorporeal oxygenation (VA-ECMO) is the only means to provide cardiopulmonary support to recovery or as bridge to transplantation. Data on the real benefit of VA-ECMO after cardiac surgery is limited and often derived from heterogeneous patient populations, which prevent conclusive results on the benefits of VA-ECMO in this setting. This issue will be investigated in the present retrospective European multicenter study. In this setting, veno-arterial extracorporeal oxygenation (VA-ECMO) is the only means to provide cardiopulmonary support to recovery or as bridge to transplantation. Data on the real benefit of VA-ECMO after cardiac surgery is limited and often derived from heterogeneous populations of patients who underwent different cardiac procedures. Patients with cardiac low-output after surgery for aortic dissection or valve surgery are expected to have different baseline characteristics (such as age and comorbidities) and underlying cardiac disease than patients undergoing isolated coronary surgery. Furthermore, available studies included patients operated two decades ago and this does not provide an exact measure of the benefits of this treatment strategy. The possible benefits of using VA-ECMO after adult cardiac surgery will be investigated in this retrospective European multicenter study.

NCT ID: NCT03479424 Enrolling by invitation - Clinical trials for Heart Failure With Reduced Ejection Fraction

Home Outpatient Monitoring and Engagement to Predict HF Exacerbation

Home Predict
Start date: October 8, 2018
Phase:
Study type: Observational

The HOME PREDICT HF study looks at new ways to predict hospitalizations for heart failure. We will use a set of devices at home and surveys to collect information about patient's health. This study uses the Eureka app, a new study app developed by the University of California, San Francisco. The study is designed to happen remotely, using this application on a patient's smartphone, so that is as convenient as possible to participate.

NCT ID: NCT03391115 Enrolling by invitation - Cancer Clinical Trials

Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness

Start date: November 15, 2017
Phase: N/A
Study type: Observational

The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting illnesses. Eliciting personal experiences is an effective way for patients to communicate their cultural values and beliefs. This study will assess how to integrate the patients' personal experience narratives into the electronic health record (EHR). The primary hypothesis is that the implementation of a patient-centered intervention to elicit personal experiences that are included in the EHR will improve patient-provider communication and patients' QoL.

NCT ID: NCT03352648 Enrolling by invitation - Heart Failure Clinical Trials

CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy: an International Registry (DERIVATE)

DERIVATE
Start date: January 2010
Phase:
Study type: Observational

The DERIVATE study was conceived to integrate the information resulted from clinical data, transthoracic echocardiography, and cardiac magnetic resonance (CMR) imaging to provide a more reliable risk stratification in patients affected by heart failure (HF) and worthy of prophylactic implanted cardioverter defibrillator (ICD) therapy. The main purposes of this multicenter registry are to: 1) determine CMR findings, and specifically late gadolinium enhancement (LGE) features, T1 mapping, and extracellular volume (ECV) that predict sudden cardiac death (SCD) and ventricular arrhythmia; 2) provide a comprehensive clinical and imaging score that effectively improves the selection of patients who deserve a prophylactic ICD therapy; 3) evaluate the contribution of machine learning to predict major adverse cardiac events (MACE) as compared to standard clinical scores.

NCT ID: NCT03351179 Enrolling by invitation - Clinical trials for Acute Myocardial Infarction

Predictors and Outcomes of In-hospital HFpEF in AMI Patients

Start date: January 1, 2013
Phase: N/A
Study type: Observational

This retrospective observation is to investigate the incidence,clinical outcomes and prognosis of hospitalized heart failure with preserved ejection fraction (HFpEF) in patients with acute myocardial infarction(AMI).

NCT ID: NCT03321279 Enrolling by invitation - Diabetes Clinical Trials

Social Incentives to Increase Mobility

MOVE IT
Start date: January 11, 2018
Phase: N/A
Study type: Interventional

This study aims to assess the effectiveness of a social incentive-based gamification intervention to increase physical activity in the 3 months after hospital discharge.