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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT04112576 Completed - Clinical trials for Heart Failure, Systolic

Physiological Signals, Activity and Posture for Surface Mounted Insertable Cardiac Monitor in Heart Failure Study

HAPI-HF
Start date: July 23, 2020
Phase:
Study type: Observational

To characterize the physiological signals collected from a Wearable Cardiac Monitor (WCM) prototype device in subjects with heart failure and preserved ejection fraction (HFpEF) and compare against signals from subjects with heart failure and reduced ejection fraction (HFrEF). To evaluate the relationship of physiological signals measured from a wearable cardiac monitor (WCM) prototype device with ECHO measures of systolic and diastolic function

NCT ID: NCT04112316 Completed - Clinical trials for Heart Failure With Reduced Ejection Fraction

Developing Oral LT3 Therapy for Heart Failure - HFrEF

DOT3HF-HFrEF
Start date: February 11, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Investigation of the safety, feasibility, and preliminary efficacy of thyroid hormone therapy with Liothyronine (LT3) in individuals with heart failure with reduced ejection fraction (HFrEF) and low triiothyronine (T3) syndrome by conducting a randomized, double-blind, placebo-controlled cross-over study with a two week washout period between treatments.

NCT ID: NCT04111536 Completed - Clinical trials for Heart Failure With Preserved Ejection Fraction

Developing Oral LT3 Therapy for Heart Failure - HFpEF

DOT3HF-HFpEF
Start date: March 8, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Investigation of the safety, feasibility, and preliminary efficacy of thyroid hormone therapy with Liothyronine (LT3) in individuals with heart failure with preserved ejection fraction (HFpEF) and low triiodothyronine (T3) syndrome by conducting a randomized, double-blind, placebo-controlled cross-over study with a two-week washout period between treatments.

NCT ID: NCT04111185 Completed - Heart Failure Clinical Trials

Daxor - Blood Volume Analysis

Start date: July 16, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to better understand blood volume status and whether knowledge of it can change and improve heart failure care.

NCT ID: NCT04111094 Completed - Heart Failure Clinical Trials

DKK3 for Prognosis and Monitoring of GFR Decline in Heart Failure

Start date: October 14, 2019
Phase:
Study type: Observational

The individual course of chronic kidney disease (CKD) may vary, and improved methods for identifying which patients will experience estimated glomerular filtration rate (eGFR) decline are needed. Recently, urinary dickkopf-3 (DKK3) has been proposed to predict eGFR decline in patients with CKD, independent of presence of albuminuria. The investigators sought to examine the association between changes in DKK3 levels and eGFR decline in patients with heart failure (HF).

NCT ID: NCT04110431 Completed - Clinical trials for Chronic Heart Failure

Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy

LBBP-RESYNC
Start date: November 14, 2019
Phase: N/A
Study type: Interventional

The present study will recruit 40 symptomatic heart failure patients with left ventricular ejection fraction (LVEF) below 35% and complete left bundle branch block(QRSd≥130 ms). Each patient was randomized to either left bundle branch pacing(LBBP) or biventricular pacing(BivP) and was followed up for at least 6 months. The objective is to compare the effects of LBBP and BivP on cardiac resynchronization in the treatment of heart failure by measurable clinical parameters.

NCT ID: NCT04096781 Completed - Stroke Clinical Trials

Engaging Patients to Help Achieve Increased Patient Choice and Engagement for AFib Stroke Prevention

ENHANCE-AF
Start date: December 18, 2019
Phase: N/A
Study type: Interventional

A multi-center, randomized controlled 2-arm trial comparing the effectiveness of an innovative shared decision-making pathway and usual care for Atrial Fibrillation Stroke Prevention

NCT ID: NCT04096040 Completed - Heart Failure Clinical Trials

Benefits of Microcor in Ambulatory Decompensated Heart Failure

BMAD-TX
Start date: November 1, 2019
Phase: N/A
Study type: Interventional

To assess investigator engagement of μCor system data in the context of heart failure management. The μCor system includes a sensor and wearable patch for fluid management.

NCT ID: NCT04084964 Completed - Heart Failure Clinical Trials

Feasibility Study of a Home Hospitalisation Strategy for Patients With Heart Failure

NWECHANCE
Start date: October 1, 2020
Phase: N/A
Study type: Interventional

This feasibility study is part of a larger interregional European project (NWE-Chance) financially supported by the 'Interreg North West Europe' program to develop and validate promising integrated eHealth applications combined with nanotechnology for hospitalisation of heart failure patients at home. For more information on this research project and the partners see http://www.nweurope.eu/nwe-chance

NCT ID: NCT04080570 Completed - Asthma Clinical Trials

Remote Physician Care for Home Hospital Patients

Start date: August 3, 2019
Phase: N/A
Study type: Interventional

This study examines the implications of providing remote physician care to home hospitalized patients compared to usual home hospital care with in-person/in-home physician visits.