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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT03187249 Recruiting - Depression Clinical Trials

Intervention Strategy in Chronic Obstructive Pulmonary Disease With Anxiety and Depression

Start date: June 15, 2017
Phase: N/A
Study type: Interventional

Anxiety and depression have negative effect on outcomes of chronic obstructive pulmonary disease (COPD). Intervention strategy including behavioral-cognitive therapy and pulmonary rehabilitation are promising in improving life quality, disease symptom and outcomes. But there's not standard algorithm in China so far. The study aims to compare the effectiveness of these interventions and develop an intervention algorithm of anxiety and depression in COPD.

NCT ID: NCT03187236 Recruiting - Depression Clinical Trials

Registry for Chronic Obstructive Pulmonary Disease With Anxiety and Depression in China

Start date: June 15, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Anxiety and depression are common comorbidities of chronic obstructive pulmonary disease (COPD). However, the exact prevalence is not known in China. COPD patients with anxiety and depression tend to have more severe symptoms and worse prognosis, but the related evidences are not strong enough. The study aim to investigate the prevalence and long-term outcome of anxiety and depression in COPD.

NCT ID: NCT03187093 Recruiting - Clinical trials for Major Depressive Disorder

Cognitive Dysfunction in MDD Patients

Start date: October 2016
Phase: Phase 4
Study type: Interventional

Major Depressive Disorder (MDD) is one of the most prevalent mental diagnosis within the worldwide population. Although there is evidence about relationship between MDD and cognitive dysfunction, still the correlations between biomarkers and the severity of the disorder or the level of cognitive dysfunction need further research. Therefore, the aim of the study is to determine such relationships in Ukrainian population.

NCT ID: NCT03185819 Not yet recruiting - Clinical trials for Depressive Disorder, Major

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Start date: August 14, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of intranasal esketamine {28 milligram (mg), 56 mg, and 84 mg} compared with psychoactive placebo (oral midazolam) in rapidly reducing the symptoms of major depressive disorder (MDD) including suicidal ideation in participants 12 to less than 18 years of age who are assessed to be at imminent risk for suicide.

NCT ID: NCT03185247 Recruiting - Depression Clinical Trials

Implementation of Transdx Group for POTS

Start date: May 26, 2017
Phase: N/A
Study type: Interventional

The proposed intervention is focused on developing and implementing a psychological approach incorporated into a group-based outpatient intervention for pediatric autonomic dysfunction. The investigators hypothesize that their intervention will result in improvements in the transdiagnostic mechanisms specifically targeted by components of their intervention including sleep, information processing, and youth/parent experiential avoidance.

NCT ID: NCT03183947 Not yet recruiting - Depression Clinical Trials

Symptom Based Treatment Affects Brain Plasticity - Cognitive Training in Patients With Affective Symptoms

APIC-II
Start date: June 2017
Phase: N/A
Study type: Interventional

The aim of the study is the examination of brain plasticity on on affective symptoms after neuromodulation with fMRI (functional magnetic resonance imaging) neurofeedback. During the fMRI neurofeedback training, patients with depression as well as patients with schizophrenia are trained to consciously regulate the activity of areas which are associated with the cognitive reappraisal of emotional stimuli.The aim is to improve the patients' subjective emotional processing and perception in everyday life as well as to investigate the impact of neurofeedback on resting-state networks in the brain. Healthy participants will be investigated as control group.

NCT ID: NCT03183505 Not yet recruiting - Clinical trials for Major Depressive Disorder

Comparison of Anyu Peibo With Placebo in Treatment of MDD,Ⅱb

Start date: June 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of Anyu Peibo Capsule comparing with placebo in the treatment of Chinese Patients with Depression. And to provide some scientific evidence for protocol designing in following phase Ⅲ clinical trial.

NCT ID: NCT03181529 Not yet recruiting - Clinical trials for Major Depressive Disorder

Effects of Psilocybin in Major Depressive Disorder

Start date: June 2017
Phase: Phase 2
Study type: Interventional

The proposed pilot study will assess whether people with major depressive disorder experience psychological and behavioral benefits and/or harms from psilocybin. This study will investigate acute and persisting effects of psilocybin on depressive symptoms and other moods, attitudes, and behaviors. Our primary hypothesis is that psilocybin will lead to rapid and sustained antidepressant response, as measured with standard depression rating scales.

NCT ID: NCT03180164 Not yet recruiting - Clinical trials for Chronic Lung Disease

Depression in Chronic Airways Diseases

Start date: July 2017
Phase: N/A
Study type: Interventional

Chronic airways diseases involve alterations in the person's social roles, relationships and self-perception so demands continual psychological adjustment . Also Kunik studied patients with chronic breathing disorders for depression and anxiety and found that 65% of patients were positive for depression and anxiety. Shackell found that patients' anxiety and fears of breathlessness and dying extended into the night and were aggravated by feelings of isolation and frustration. One patient reported that they often thought 'am I going to see the next morning?'

NCT ID: NCT03178903 Recruiting - Depression Clinical Trials

tDCS for Increasing Exercise Adherence in Depressed Individuals

StRIDE
Start date: February 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the efficacy of tDCS (transcranial direct current stimulation) for increasing exercise adherence among low active individuals with elevated depressive symptoms. The investigators expect that this project will contribute much needed knowledge about the role that tDCS can play in changing the affective experience of exercise.