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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT03796325 Completed - Depression Clinical Trials

Depressive State After Sleeve Gastrectomy

Start date: January 1, 2013
Phase:
Study type: Observational [Patient Registry]

Obesity is an epidemic disease that continues to increase causing morbidity and mortality to those who suffer. Obese patients suffer, frequently, from a depressive state, anger, and emotional disturbances. It cannot be recognized and depression causes obesity affecting eating habits or obesity causes depression based on physical, social and occupational limitations. Many times we see that obese patients are discriminated in every sense of daily life increasing their depressive state. The best treatment for obesity is bariatric surgery that causes a sufficient weight loss to correct sleep apnea, diabetes, hypertension, and many other co-morbidity. The study is based on elucidating the effect of sleeve gastrectomy in obese patients suffering from depression

NCT ID: NCT03795480 Completed - Depressive Symptoms Clinical Trials

Online Intervention for Depression: MOOD

MOOD
Start date: May 7, 2018
Phase: N/A
Study type: Interventional

The study aims to examine the efficacy and acceptance of a self-help internet intervention "MOOD" in a sample of individuals with depressive symptoms. It is tested whether depressive symptomatology decreases in the intervention group compared to a wait-list control group. Further aims are to ascertain changes in self-worth and quality of life, to assess subjective evaluation of the program and to examine whether expectations of the program's helpfulness would predict symptom reduction.

NCT ID: NCT03785652 Completed - Clinical trials for Major Depressive Disorder

Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LY03005 Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD)

Start date: October 9, 2015
Phase: Phase 1
Study type: Interventional

This study was a multicenter, randomized, double-blind, placebo, parallel-controlled, dose-finding Phase II clinical trial to find the optimal dose of LY03005 Extended-release Tablets for the treatment of MDD and to evaluate the preliminary efficacy and safety, providing a basis for the design of phase III clinical trials and the determination of dosing regimens.

NCT ID: NCT03759171 Completed - Depression Clinical Trials

Music-instruction Intervention for Treatment of Post-traumatic Stress Disorder

Start date: October 1, 2010
Phase: N/A
Study type: Interventional

The purpose of this study was to examine the feasibility and potential effectiveness of an active, music-instruction intervention in improving psychological health and social functioning among Veterans suffering from moderate to severe Post-traumatic Stress Disorder (PTSD).

NCT ID: NCT03752346 Completed - Parkinson's Disease Clinical Trials

Multimodal Exercise Program on Parkinson's Disease Patients With Depression

Start date: March 2016
Phase: N/A
Study type: Interventional

Depression symptoms are common in Parkinson's Disease, it affects health-related quality of life. The evidence showed that exercise improved depression and HRQOL in PD patients. However, studies rarely considered the appropriate exercise program for PD patients, we want to find the best exercise program for PD patients.

NCT ID: NCT03733574 Completed - Clinical trials for Major Depressive Disorder

A Study of LY03005 vs Pristiq

Start date: June 19, 2018
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in healthy subjects between 18 and 50 years of age.

NCT ID: NCT03732378 Completed - Clinical trials for Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder: A Randomized Controlled Trial

Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder.

Start date: April 27, 2017
Phase: N/A
Study type: Interventional

Background: Patients with major depressive disorder have prominently been reported to be related with subnormal polyunsaturated omega-3 fatty acids levels, importantly low docosahexaenoic acid and eicosapentaenoic acid in plasma and dietary intake. However, more randomized controlled trials are needed to support its importance in management of depression. Objective: To explore polyunsaturated omega-3 fatty acid role in major depressive disorder management. Materials & Methods: Seventy patients 20 to 40 yeas, who were already diagnosed with depression and taking antidepressant treatment, were selected at department of psychiatry and behavioral sciences Kind Edward Medical University Lahore, and assigned into 2 groups, i.e. Intervention and control, by simple random lottery method. For twelve weeks, intervention group advised to take one omega-3 (300mg EPA, eicosapentaenoic acid and 200mg DHA docosahexaenoic acid), or placebo (500 mg corn oil) capsules once daily with meal. Beck Depression Inventory (BDI) scale was used to assess the depression. Demographic information was collected by using a structured questionnaire.

NCT ID: NCT03731481 Completed - Obesity Clinical Trials

Virtual Lifestyle Medicine Comparative Effectiveness Research

Start date: May 31, 2017
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness of two online Lifestyle Medicine programs. Participants will be randomized by residence, urban vs. rural, into one of two Lifestyle Medicine programs.

NCT ID: NCT03721588 Completed - Clinical trials for Depressive Disorder, Major

Clinical and Suicidal Features of Urban, Turkish Middle Age Depressive Patients With Comorbid ADHD

Start date: September 1, 2015
Phase:
Study type: Observational

In the presence of attention deficit hyperactivity disorder (ADHD) together with additional psychiatric diseases, the treatment process and prognosis of both ADHD and psychiatric comorbidity are adversely affected. The aim of this study is to compare the characteristics concerning the suicidal behavior of the patients with major depressive disorder (MDD) who have (ADHD+) or do not have (ADHD-) adult ADHD comorbidity and their responses to depression treatment. 96 inpatients were included in the study. Socio-demographic data form, Hamilton Depression Scale (HDRS), Wender Utah Rating Scale (WURS), Adult ADD/ADHD DSM IV- Based Diagnostic Screening and Rating Scale (A-ADHD), Personal and Social Performance Scale (PSP) were applied to the cases. In the study, depression starts at an early age in individuals with comorbid ADHD and the depression treatment progress changes negatively. This group of patients is at greater risk in terms of suicidal behavior. For these reasons, clinicians should be careful during ADHD and depression management in adults.

NCT ID: NCT03714204 Completed - Depression Clinical Trials

Academic Physician Burnout and Transcendental Meditation

Start date: August 1, 2015
Phase: N/A
Study type: Interventional

This research study will examine the effects of the Transcendental Meditation (TM) technique on academic physician burnout, depression, insomnia, perceived stress, and resilience through a mixed methods approach.