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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT03316846 Active, not recruiting - Anxiety Clinical Trials

Internet-delivered Cognitive Behavioral Therapy for Patients With Chronic Pain and Psychiatric Distress

Start date: September 13, 2016
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial studying the efficacy of an iCBT treatment for patients with chronic pain and comorbid psychiatric distress. Half the participants will receive treatment at first, while the other half serve as a control group. After the first group has received treatment, the same program will be offered to participants in the control group. Treatment will be tailored on the level of individual participants, enabling individuals suffering a wide range of problems to be recruited. The treatment will consist of a 10-week guided self-help program, followed by a booster program and follow-up one year later. During the curse of the treatment the participants will be guided via text communication by a licensed psychologist or a candidate psychologist on their last year of studies. The primary hypothesis is that an individually tailored CBT-treatment administered through the internet can be beneficial for patients suffering from chronic pain and comorbid psychiatric distress. We expect that patients in the treatment group will show reduced levels of disability, depression and anxiety, while improving on scales measuring coping and quality of life.

NCT ID: NCT03308864 Active, not recruiting - Depression Clinical Trials

Strong Connections

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two talking forms of therapy designed to help reduce depressive symptoms in teenagers: Interpersonal Psychotherapy for Adolescents and Treatment as Usual.

NCT ID: NCT03299127 Active, not recruiting - Depression Clinical Trials

Imagery Rescripting in Depression

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Depression is among the world's leading causes of disability. To fill the existing treatment gap, psychological online interventions (POIs) and Internet-based treatment, including bibliotherapy with PDF manuals (POIs), are increasingly recommended as they are easily accessible and deemed an initial alternative approach. The present trial aims to evaluate imagery rescripting. With the help of various techniques, the approach aims to edit negative memories and rewrite a "happy end". To the best of our knowledge, imagery rescripting has never been tested as a self-help intervention. A large sample of patients with primary or secondary depression (N = 120) will be recruited and randomly allocated to either the intervention group or a wait-list control group. The intervention group consists of two subgroups that will receive either a full or brief version of a manual teaching them imagery rescripting. Participants will be assessed at baseline and six weeks later. A follow-up assessment will be completed six months later. The primary outcome measure is the Beck Depression Inventory II.

NCT ID: NCT03285230 Active, not recruiting - Breast Cancer Clinical Trials

The French E3N Prospective Cohort Study

Start date: June 15, 1990
Phase: N/A
Study type: Observational

The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women. The participants were insured through a national health system that primarily covered teachers, and were enrolled from 1990 after returning baseline self-administered questionnaires and providing informed consent. The cohort comprised nearly 100 000 women with baseline ages ranging from 40 to 65 years. Follow-up questionnaires were sent approximately every 2-3 years after the baseline and addressed general and lifestyle characteristics together with medical events (cancer, cardiovascular diseases, diabetes, depression, fractures and asthma, among others). The follow-up questionnaire response rate remained stable at approximately 80%. A biological material bank was generated and included blood samples collected from 25 000 women and saliva samples from an additional 47 000 women. Ageing among the E3N cohort provided the opportunity to investigate factors related to agerelated diseases and conditions as well as disease survival.

NCT ID: NCT03256760 Active, not recruiting - Clinical trials for Depression in Old Age

Sleep and Healthy Aging Research for Depression (SHARE-D) Study

Start date: March 1, 2017
Phase: Phase 1
Study type: Interventional

Late-life depression is a significant public health concern, and effective interventions for prevention and treatment are needed. Insomnia and inflammation are modifiable targets for depression prevention, and this study is significant in using an experimental approach (i.e., inflammatory challenge) to probe acute inflammatory- and depression responses as a function of insomnia, which will inform identification of molecular targets for pharmacologic interventions, and improvement of insomnia treatments to prevent depression in older adults. Project

NCT ID: NCT03236948 Active, not recruiting - Depressive Symptoms Clinical Trials

RCT of the Effectiveness of the WfWI Intervention in Afghanistan

Start date: October 2016
Phase: Phase 3
Study type: Interventional

This is an individually randomised control trial to assess the effectiveness of a livelihoods and social empowerment intervention, delivered by Women for Women International, on married women's experiences of intimate partner violence in Afghanistan. It has a 22 month follow up.

NCT ID: NCT03221127 Active, not recruiting - Depression Clinical Trials

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Start date: March 1, 1984
Phase: N/A
Study type: Observational

To determine associations between dietary factors and risk of major chronic diseases and their risk factors

NCT ID: NCT03207438 Active, not recruiting - Clinical trials for Depressive Disorder, Major

Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression

Start date: April 2006
Phase: Phase 4
Study type: Interventional

In essence the researchers are hoping to test two separate hypotheses (described below in the form of research questions). Therefore, the proposed analysis has been outlined according to each hypothesis. Hypothesis 1: Is low-dose quetiapine (50 mg/day) more effective for patients with depression who have insomnia at treatment baseline? (Stated differently: is low-dose quetiapine 50 mg/day effective as monotherapy for patients with depression regardless of whether or not they have insomnia at baseline?). Hypothesis 2: Is high-dose quetiapine (150 - 300 mg/day) more effective for patients presenting with melancholic depression at treatment baseline?

NCT ID: NCT03153904 Active, not recruiting - Depression Clinical Trials

Connecticut Child STEPs

Start date: October 2013
Phase: N/A
Study type: Interventional

Connecticut Child STEPS is a randomized controlled trail investigating the effectiveness of MATCH-ADTC in treating anxiety, depression, trauma, and/or behavioral problems in children seeking services at four Department of Children and Families (DCF) funded clinics in the state of Connecticut. The study will evaluate child outcomes following two forms of therapist training in the MATCH model.

NCT ID: NCT03123991 Active, not recruiting - Depression Clinical Trials

Applying the Spanish Version of the UP-A as a Universal School-based Anxiety and Depression Prevention Program

Start date: October 10, 2016
Phase: N/A
Study type: Interventional

The current study proposes to extend transdiagnostic treatment research to adolescents by establishing initial pre to post-treatment and follow-up outcomes associated with the use of the Spanish Version of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents (UP-A; Ehrenreich-May, Bilek, Buzzella, Kennedy, Mash, & Bennett, 2016) as a universal school-based preventive intervention.