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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT05292014 Recruiting - Clinical trials for Ischemic Heart Disease

ANGIOLITE PMCF Study ( rEPIC04F )

rEPIC04F
Start date: September 26, 2022
Phase:
Study type: Observational

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Angiolite sirolimus eluting stent to meet EU Medical Device regulation (MDR) requirements in all the CONSECUTIVE patients treated with Angiolite sirolimus eluting stent.

NCT ID: NCT05290324 Completed - Clinical trials for Coronary Artery Disease

Propofol or Midazolam for Sedation and Early Extubation Following Coronary Artery Bypass Graft Surgery

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Propofol and midazolam are used frequently as sedating agents among patients who undergo coronary artery bypass graft surgery but no study in Pakistan has been done to compare their effectiveness aiming early extubation.

NCT ID: NCT05288361 Recruiting - Clinical trials for Endothelial Dysfunction

The DISCOVER INOCA Prospective Multi-center Registry

DISCOVER INOCA
Start date: September 14, 2022
Phase:
Study type: Observational [Patient Registry]

The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.

NCT ID: NCT05286593 Completed - Clinical trials for Coronary Artery Disease

3D PET Myocardial Blood Flow and Rb82 Infusion Profiles

Start date: December 28, 2021
Phase: Phase 4
Study type: Interventional

The investigators seek to test bolus infusions (50ml/min) vs. slow infusions (20 ml/min) of Rb-82 on metrics of coronary blood flow assessed on a modern 3D PET/CT.

NCT ID: NCT05280782 Completed - Clinical trials for Coronary Artery Disease

Development and Translation of Generator-Produced PET Tracer for Myocardial Perfusion Imaging-Dosimetry Group

GALMYDAR
Start date: January 5, 2022
Phase: Early Phase 1
Study type: Interventional

This study is a single center, early phase 1 clinical imaging study designed to assess the dosimetry of 68Ga-Galmydar for PET/CT imaging.

NCT ID: NCT05279651 Recruiting - Myocardial Ischemia Clinical Trials

Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS)

PREVENT-MINS
Start date: June 13, 2022
Phase: Phase 3
Study type: Interventional

This study is a multicentre, randomized controlled trial of ivabradine versus placebo.

NCT ID: NCT05271591 Completed - Clinical trials for Cardiovascular Diseases

Generalizability of REDUCE-IT Results to People of South Asian Descent With Atherosclerotic Cardiovascular Disease in Canada (REDUCE-IT Canada SA)

Start date: March 5, 2022
Phase:
Study type: Observational

The REDUCE-IT Canada SA Study is a cross-sectional study aiming to determine the proportion of study participants who meet the Health Canada-approved indication for icosapent ethyl (IPE;Vascepa®).

NCT ID: NCT05271448 Recruiting - Clinical trials for Chronic Kidney Diseases

Continuing or Discontinuing ACE/ARBs in Patients With Chronic Kidney Disease Undergoing Coronary Angiography

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Contrast induced nephropathy (CIN) is a well-known possible complication of percutaneous coronary intervention (PCI) with an incidence varies from 3.3% to 14.5% in patients undergoing PCI. Many previous randomized and non-randomized studies have shown very conflicting results regarding the use of ACE-Is prior to coronary angiography, and whether it decreases or increases the risk of CIN. The importance of this study is to help find an acceptable and reliable answer for the use of ACE-I/ARBs prior to cardiac catheterization. This research aims to study the effect of withholding ACE-Is or ARBs on the incidence of contrast induced nephropathy in patients undergoing coronary angiography who have chronic kidney disease (GFR<60 ml/min/1.73 m2) and to help build evidence-based data and guidelines on the safety of continuing or withholding ACE-I/ARBs pre contrast administration.

NCT ID: NCT05270330 Recruiting - Clinical trials for Coronary Artery Disease

Plaque Stability and Metabolomics in Coronary Heart Disease

Start date: July 1, 2021
Phase:
Study type: Observational

At present, the investigators don't know the relationship between plaque stability and the metabonomics changes. In the present study, investigators will evaluate the plaque stability by intravascular unltrasound in stable coronary heart patients, and metabonomics was also assessed by high throughput sequencing. Statistic analysis were carried out to analyze the correlation between plaque stability and metabonomics changes among these study patients.

NCT ID: NCT05267990 Enrolling by invitation - Clinical trials for Coronary Heart Disease

Coronary Artery Calcium-guided Primary Prevention of Major Coronary Heart Disease in Asymptomatic Diabetes

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

To evaluate benefits of primary prevention of major coronary heart disease for asymptomatic coronary artery disease in type 2 diabetes mellitus based on the coronary artery calcium score Our proposal 1. Based on CAC score, primary early prevention could reduce incidence of major coronary heart disease (CHD) including cardiac mortality, acute myocardial infarction, coronary revascularization 2. based on CAC score, primary early prevention could reduce all cause mortality, cardiac mortality, cardiovascular disease, heart failure, ischemic stroke, heart failure associated hospitalization and chronic kidney disease and related clinical cost effect