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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03257683 Enrolling by invitation - Clinical trials for Severe Coronary Artery Disease

RANOLAZINE STUDY: Speckle Tracking Derived Myocardial Strain

Start date: April 14, 2017
Phase: N/A
Study type: Observational

The purpose of this study is to collect data to determine if the medication, Ranolazine, effects heart muscle function in patients who have areas of non-revascularizable heart muscle.

NCT ID: NCT03200990 Enrolling by invitation - Clinical trials for Coronary Artery Disease

PULsecath mechanicaL Support Evaluation

PULSE
Start date: December 2016
Phase: N/A
Study type: Interventional

The objective of this study is to determine ventricular loading conditions during and after PulseCath® iVAC2L support, and assess its impact on specific load dependent humoral factors and cardiac enzymes. These specific patterns are so far unknown and will be compared with the validated FDA-cleared and CE marked Impella CP. Ten cases with Impella CP will be performed in this study to obtain the exact same measurements for comparing purposes.

NCT ID: NCT03066050 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Long Term Follow Up for CTSN Mitral Valve Repair Studies

Start date: May 3, 2017
Phase: N/A
Study type: Observational

This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about patients' health 5-10 years after their mitral valve surgeries. The investigators will collect long-term health information on SMR and MMR trial participants using electronic medical records, patient and/or family input, public records, and healthcare- and vital status-related databases.

NCT ID: NCT03057561 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Efficacy of Dotarem® (Gd-DOTA) Versus Magnevist® (Gd-DTPA) for Late Gadolinium Enhancement Cardiac Magnetic Resonance

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

This project is designed to demonstrate equivalence of Dotarem enhanced LGE-CMR (late gadolinium enhancement cardiac MRI) with Magnevist enhanced LGE-CMR from the standpoint of visual image quality, quantitative image quality, and association with clinical outcomes.

NCT ID: NCT03052803 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Comparison of Devices Evaluating Fractional Flow Reserve in Coronary Arteries

FFR-DS
Start date: February 1, 2017
Phase: N/A
Study type: Observational

The aim of the study is to compare different devices available to measure fractional flow reserve (FFR) in coronary arteries.

NCT ID: NCT03051048 Enrolling by invitation - Clinical trials for Coronary Heart Disease

System Delay and Clinical Outcome Among Chinese Patients With AMI Treated With Reperfusion Therapy (MOODY Study)

MOODY
Start date: January 1, 2004
Phase: N/A
Study type: Observational

Acute myocardial infarction (AMI) pose a pool clinical outcome to men and women whom treatment was delayed. However, reperfusion time was limited in previous studies. To evaluate the system delay and clinical outcomes among Chinese patients with AMI, consecutive inpatient case prospectively collected from 2004 to 2016. Basic data and innovative evidence will accelerate evidence-based clinical practice and policy making, and improve AMI patients outcomes finally.

NCT ID: NCT02972242 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Focused Field of View Calcium Scoring Prior to Coronary CT Angiography

FOCUS-CCTA
Start date: November 2014
Phase: N/A
Study type: Interventional

Coronary computed tomography angiography (CCTA) is a frequently performed test for the diagnosis and/or exclusion of coronary artery disease (CAD) in appropriately selected patients. The performance of non-contrast computed tomography for the detection and quantification of coronary calcification is typically performed prior to CCTA in an effort to identify significant calcification which may influence subsequent data acquisition during the CCTA. However, performance of calcium scoring adds significant radiation and most coronary calcification is proximal in its location, potentially visualized using a focused non-contrast scan. The purpose of this study is to prospectively compare the usefulness of a modified non-contrast CT, using a significantly shorter scan length and lower radiation parameters, as compared to standard coronary artery calcium scanning for the detection of coronary calcification that may influence subsequent CCTA performance.

NCT ID: NCT02932553 Enrolling by invitation - Clinical trials for Angina Pectoris, Variant

BVS Implantation in Patients With Variant Angina and MODerate Coronary Artery Disease

BIVA-pilot
Start date: April 19, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether BVS(Bioresorbable Vascular Scaffold) implantation with optimal medical therapy can improve the outcome of patients with variant angina and moderate coronary artery disease.

NCT ID: NCT02931331 Enrolling by invitation - Coronary Disease Clinical Trials

Coronary Revascularization Assessed by Stress PET

Start date: March 2016
Phase: N/A
Study type: Observational [Patient Registry]

Regional absolute myocardial blood flow during stress (sMBF) as measured by Positron Emission Tomography (PET) improves post mechanical revascularization provided there is a baseline stress induced perfusion defect. Coronary revascularization performed on regions without a stress induced perfusion defect does not increase the sMBF.

NCT ID: NCT02894255 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Prospective Multicenter Registry of Hybrid Coronary Artery Revascularization Combined With Surgical Bypass and Percutaneous Coronary Intervention Using Everolimus Eluting Metallic Stents

Start date: September 2016
Phase: Phase 4
Study type: Interventional

This prospective multicenter registry evaluates the efficacy of hybrid coronary revascularization (HCR) combining coronary artery bypass surgery (CABG) and percutaneous coronary intervention (PCI) in the treatment of multivessel coronary artery disease. CABG is to be performed in the left anterior descending artery and the left circumflex artery using only arterial grafts, whereas PCI is to be conducted for the treatment of significant stenotic disease in the right coronary artery with everolimus-eluting stents (EESs). This research plans to involve patients scheduled for coronary revascularization for multivessel coronary artery disease who consent to participate in the registry.