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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03488654 Terminated - Clinical trials for Coronary Artery Disease

CMR-Lupus Comprehensive Approach by Cardiovascular Magnetic Resonance Tomography

Start date: July 2010
Phase:
Study type: Observational

In systemic lupus erythematosus (SLE), cardiac manifestations, e.g. coronary artery disease (CAD) and myocarditis are leading causes of morbidity and mortality. The prevalence of subclinical heart disease in SLE is unknown. We studied whether a comprehensive cardiovascular magnetic resonance (CMR) protocol may be useful for early diagnosis of heart disease in SLE patients without known CAD

NCT ID: NCT03236311 Terminated - Clinical trials for Microvascular Coronary Artery Disease

A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI

Start date: October 12, 2017
Phase: Phase 2
Study type: Interventional

Primary Objective: To assess the effects of SAR407899 on coronary vasomotor function using the coronary flow reserve (CFR) in patients with microvascular angina (MVA) and/or persistent stable angina despite angiographically successful percutaneous coronary intervention (PCI). Secondary Objectives: - To assess the effects of SAR407899 on quality of life using Seattle Angina Questionnaire physical limitation domain (SAQ-PL) in patients with MVA and/or persistent stable angina despite angiographically successful PCI. - To assess the safety of SAR407899 in patients with MVA and/or persistent stable angina despite angiographically successful PCI with a focus on identified risks such as hypotension and orthostatic hypotension. - To assess SAR407899 plasma concentrations in MVA patients and/or persistent stable angina despite angiographically successful PCI.

NCT ID: NCT03207646 Terminated - Clinical trials for Coronary Artery Disease

Smartphone GUIded MeDication AdherencE and Rehabilitation in Patients With Coronary Artery Disease

smartGUIDE
Start date: July 19, 2017
Phase: N/A
Study type: Interventional

This study evaluates a smartphone-based cardiac rehabilitation program in adults with coronary artery disease. Half of patients will participate in a smartphone-based cardiac rehabilitation program while the other half will receive standard-of-care.

NCT ID: NCT03184805 Terminated - Clinical trials for Coronary Artery Disease

STOPping Versus Continuing Antiplatelet Therapy During Noncardiac Surgery and Procedures After Next Generation Drug-eluting Stent Implantation

Start date: June 23, 2017
Phase: N/A
Study type: Interventional

Most previous trials support the absolute increase in bleeding risk with perioperative administration of antiplatelet. Furthermore, recent studies demonstrated that perioperative major bleeding may be related to increase cardiovascular risk. The investigators will compare the efficacy and safety of continuing versus stopping antiplatelet therapy during perioperative period in patients underwent PCI(Percutaneous Coronary Intervention) with next generation DES(Drug Eluting Stent).

NCT ID: NCT03068286 Terminated - Depression Clinical Trials

iCBT for Long-term Conditions in IAPT

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

SilverCloud provides internet-delivered interventions for depression and anxiety in NHS Mental Health Services. The interventions have proved successful in the management of depression and anxiety for clients presenting to mental health services, with recovery rates exceeding the national standard. Recently SilverCloud has embarked on tailoring the interventions for patients with long-term conditions including COPD, pain and diabetes. The purpose of the customisation is to make the interventions more meaningful and relevant to patients with LTCs, but all the while having the same goal of addressing depression and anxiety disorders. In doing so it would be expected that individuals might be in a better position to effectively self-manage their LTC. The current study, therefore, seeks to assess the possible effectiveness of implementing customised internet-delivered interventions for depression and anxiety for people with long-term conditions presenting to NHS mental health services.

NCT ID: NCT02915991 Terminated - Clinical trials for Coronary Artery Disease

User Evaluation Study of SyncVision System With Software v4.X

Prepare II
Start date: November 2016
Phase:
Study type: Observational

This is a prospective, single-arm, unblinded, case observation study evaluating a commercially released 'Conformité Européenne' (CE)-mark co-registration software system along-side of a commercially- released CE-mark coronary physiology and X-ray system during routine clinical workflow. The purpose of this study is to collect Professional user feedback regarding clinical utility of the SyncVision 4.X system.

NCT ID: NCT02893579 Terminated - Clinical trials for Ischemic Heart Disease

Stress Reduction Intervention for Women With Ischemic Heart Disease

Start date: March 6, 2018
Phase: N/A
Study type: Interventional

This is a single center, randomized controlled trial which will include women with ischemic heart disease to receive either a self-directed stress reduction program delivered through a smart-phone application or activity tracking only for the first month ("early SR intervention" and "delayed SR intervention", respectively). Patients will be monitored for 1 month for application use and step counts via telephone or email interview and/or collection of screen-captured data. Baseline questionnaires will be repeated at the end of one month to assess for all primary and secondary measures, at which time the control group (activity tracking only) will be introduced to the intervention program. The early SR intervention group will not receive a new intervention but will be encouraged to continue using the app. Data will be collected for an additional 2 months with all participants in both groups. After the three-month study period, the study will close with the collection of final questionnaire data.

NCT ID: NCT02831205 Terminated - Clinical trials for Percutaneous Transluminal Coronary Angioplasty

Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents for Diffuse Long Coronary Artery Disease

ABSORB-LONG
Start date: July 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether ABSORB bioresorbable vascular scaffold is non-inferior to XIENCE everolimus-eluting cobalt-chromium stent with respect to target-lesion failure (TLF) at 1 year.

NCT ID: NCT02814578 Terminated - Clinical trials for Coronary Artery Disease

Assessment of Coronary Artery Lesion Using Optical Coherence Tomography Versus IntraVascular Ultrasound for BiorEsorbable Vascular Scaffold Implantation

ACTIV-BVS
Start date: July 31, 2017
Phase: N/A
Study type: Interventional

The primary objective is to determine whether IVUS- (vs. OCT-) guided BVS implantation is non-inferior to achieve a large in-scaffold minimal lumen area (primary endpoint) measured by OCT at 1-year follow-up.

NCT ID: NCT02739685 Terminated - Clinical trials for Coronary Artery Disease

Bioresorbable Vascular Scaffolds Versus Stents in Patients With Chronic Total Occlusion

SCORE-CTO
Start date: September 2016
Phase: Phase 4
Study type: Interventional

The purpose of the current study is to demonstrate non-inferiority of everolimus-eluting bioresorbable vascular scaffold to everolimus-eluting stents in patients with chronic total occlusion regarding the antirestenotic efficacy at 8 to 10-month angiographic follow-up.