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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03587922 Recruiting - Clinical trials for Coronary Artery Disease

FANTOM Post Market Clinical Trial

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Post Market study of the Fantom Sirolimus-Eluting Bioresorbable Coronary Scaffold

NCT ID: NCT03584464 Recruiting - Clinical trials for Coronary Artery Disease

RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

To observe the continued performance of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in a real-world more-comer population. To collect data on the safety and efficacy of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in bifurcated lesions.

NCT ID: NCT03583320 Recruiting - Clinical trials for Coronary Artery Disease

Trial of Cardiac CT in Acute Chest Patients With Intermediate Level Initial High-sensitivity Cardiac Troponin

PROTECCT
Start date: January 12, 2018
Phase: N/A
Study type: Interventional

Patients who present to the emergency department (ED) with acute chest pain (ACP) possibly due to Coronary artery disease (CAD), with a normal heart tracing (ECG), need to have further troponin blood tests to confirm or exclude a heart attack. After initial troponin testing, a significant 50-85% of patients are said to be in an "observational zone" as one cannot confirm or exclude a diagnosis of a heart attack. Even after repeat blood testing, 22-33% remain in this "observational zone". These patients can be challenging to manage as they are not safe to be discharged home, but they also cannot be treated as a heart attack. This contributes to ED overcrowding and uncertainty in treatment plans.

NCT ID: NCT03583229 Recruiting - Clinical trials for Platelet Dysfunction

Coronary Artery Disease After Heart Transplantation

ECP
Start date: October 13, 2016
Phase: N/A
Study type: Interventional

This study evaluates coronary artery disease after heart transplantation and its relation to platelet function. Furthermore, we will evaluate extracorporeal photopheresis as treatment of coronary artery disease after heart transplantation.

NCT ID: NCT03572023 Recruiting - Clinical trials for Acute Coronary Syndrome

Investigation of the Heart and the Clinical Course of Acute Coronary Syndrome in Patients With Non-obstructive Lesion of the Coronary Arteries

MINOCA
Start date: May 28, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to improve the differential diagnosis and clinical outcomes of acute coronary syndrome with non-obstructive coronary arteries, to investigate the relationship between the structural and functional state of the heart and the clinical course of the disease.

NCT ID: NCT03556644 Recruiting - Clinical trials for Coronary Artery Disease

Evaluation of CTCA in Assessing Plaque Pathology and Physiology

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Computed tomographic coronary angiography (CTCA) has been recently introduced to non-invasively evaluate coronary artery pathology. Histology and intravascular ultrasound imaging studies have demonstrated that CTCA enables identification of plaque characteristics associated with increased vulnerability (i.e., plaque burden and composition) and allows assessment of vessel physiology (i.e., local haemodynamic forces), and reports have shown that CTCA can predict atherosclerotic evolution and detect lesions that will progress and cause cardiovascular events. Despite the wealth of data provided, CTCA has still a limited role in the study of atherosclerosis. Prior to unlocking the full potential of CTCA and enable its broad use, further work is needed to develop user-friendly processing tools that will allow fast and accurate analysis of CTCA, and examine in detail the accuracy of modern CTCA imaging in assessing plaque pathology. In this application, the investigators aim 1) to develop a CTCA analysis system that will enable fast segmentation, reliable coronary reconstruction and blood flow simulation in a user-friendly environment and 2) validate the efficacy of state-of-the-art CTCA for assessment of coronary plaque morphology and physiology against intravascular plaque imaging using hybrid near infrared spectroscopy-intravascular ultrasound.

NCT ID: NCT03552432 Recruiting - Clinical trials for Coronary Artery Disease

The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography

ALTAIR
Start date: September 26, 2017
Phase: Phase 4
Study type: Interventional

the purpose of this study is to show that alirocumab with statin therapy have a s tronger stabilizing effect on vulnerable plaque in coronary artery disease than statin alone administration

NCT ID: NCT03543241 Recruiting - Clinical trials for Coronary Artery Disease

MyoStrain CMR Testing of Ischemia With Low Levels of Stress

Start date: November 8, 2017
Phase:
Study type: Observational

This prospective, observational study evaluates the accuracy of stress testing with the MyoStrain SENC CMR Imaging System to detect myocardial ischemia and viability in patients with suspected coronary artery disease using low levels of stress.

NCT ID: NCT03539354 Recruiting - Clinical trials for Coronary Artery Disease

TEmporary Spinal CoRd StiMulatIon to PrevenNt Atrial FibrillaTION AFter Cardiac Surgery

TerminationAF
Start date: July 1, 2018
Phase: N/A
Study type: Interventional

To compare of atrial arrhythmia incidence in patients with coronary artery disease and atrial fibrillation history, undergoing either coronary artery bypass grafting plus temporary spinal cord stimulation or coronary artery bypass grafting alone

NCT ID: NCT03538886 Recruiting - Clinical trials for Coronary Artery Disease

Nordic-Baltic Coronary Revascularization Study in Patients With Proximal Left Descending Coronary Artery (LAD) Lesion.

NOBLE-LAD
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The Nordic-Baltic Heart Team Initiative for improved long-term coronary artery revascularization outcome compares quality of life and survival after coronary bypass grafting (CABG) vs. percutaneous coronary intervention (PCI) in patients with 1-vessel disease and proximal stenosis of the anterior descending artery (LAD/in patients with isolated proximal left descending coronary artery (LAD) lesion