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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03194711 Active, not recruiting - Coronary Disease Clinical Trials

BVS-OCT Imaging Study

Start date: May 30, 2017
Phase: N/A
Study type: Observational

The single center retrospective study evaluates the acute and long term outcomes of bioabsorbable drug-eluting scaffolds (BVS) implantation in 50 consecutive coronary artery disease (CAD) patients using optical coherence tomography (OCT) imaging.

NCT ID: NCT03192891 Active, not recruiting - Myocardial Ischemia Clinical Trials

Clinical Impact of Stress CMR Perfusion Imaging

SPINS
Start date: March 1, 2017
Phase: N/A
Study type: Observational

Numerous single-center studies have indicated gadolinium-enhanced stress CMR perfusion imaging has excellent diagnostic accuracy for coronary artery disease and negative clinical event rates, with its diagnostic accuracy exceeding nuclear scintigraphy. However, current prognostic evidence supporting clinical use of stress CMR is limited by study size, single-center settings with a predominance of academic centers, and a lack of "real-world" study design. Large-scale multicenter real-world evidence from a registry will provide the much needed information to guide evidence-based clinical adaptation that benefits patient care.

NCT ID: NCT03176810 Active, not recruiting - Coronary Disease Clinical Trials

Comparison Between Optimal Coherence Tomography Guidance and Angiography Guidance in Percutaneous Coronary Intervention

COCOA
Start date: April 1, 2017
Phase: N/A
Study type: Interventional

The present study aims to demonstrate the superiority of optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) compared with Angiography-guided PCI.

NCT ID: NCT03159559 Active, not recruiting - Clinical trials for Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease

PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes

Start date: January 2017
Phase: Phase 4
Study type: Interventional

This study is undertaken to determine if intravenous Lipo-PGE1 therapy would improve coronary microvascular perfusion in patients with ischemic heart disease by CMRI.

NCT ID: NCT03133689 Active, not recruiting - Clinical trials for Coronary Heart Disease

Alcohol Consumption and Coronary Heart Disease Onset

Start date: March 1, 2017
Phase: N/A
Study type: Observational

The primary aim of this study is to examine if long-term patterns of alcohol consumption are associated with time-to-onset for incident coronary heart disease (fatal and non-fatal), using data from multiple cohorts.

NCT ID: NCT03066141 Active, not recruiting - Clinical trials for Coronary Artery Disease

Evaluation of Association Between Obstructive Sleep Apnea and the Severity of Coronary Artery Disease

Start date: February 14, 2017
Phase: N/A
Study type: Observational [Patient Registry]

It is widely accepted that coronary artery disease (CAD) is related to a high mortality. It is predicted that an increase of approximately 21.3 million cardiovascular events and 7.7 million cardiovascular deaths over 2010 to 2030 in China.1 Male sex, diabetes mellitus, hypertension, hypercholesterolemia, obesity and smoking are all traditionally considered as risk factors for CAD. In recent decades, tremendous progress toward the prevention and treatment of traditional cardiovascular risk factors have helped decrease the morbidity and mortality from CAD, but the condition remains a major public health challenge worldwide. Looking into the other potential risk factors (OSA) for CAD, it may help to develop additional preventative strategies and further reduce the incidence and mortality of CAD.

NCT ID: NCT03049657 Active, not recruiting - Clinical trials for Coronary Artery Disease

Efficacy of Angiolite Stent vs a Second-generation Drug-eluting Stent Xience for Percutaneous Coronary Intervention

Start date: February 2, 2016
Phase: N/A
Study type: Interventional

Clinical trial with an "European Community marked" medical device in patients with ischemic heart disease and clinical indication of coronary revascularization with drug-eluting stent. Clinical follow-up will be done according to this way: first month telephone or face-to-face interview and at 6 ± 1 month an Angiography follow up + OCT (optical coherence tomography) A randomized clinical trial to compare the efficacy of Angiolite Stent versus a second-generation drug-eluting stent such as Xience stent.(non-inferiority design)

NCT ID: NCT03049085 Active, not recruiting - Clinical trials for Coronary Artery Disease

Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting

Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

Effect of Preoperative Aspirin in patients undergoing Off-pump Coronary Artery Bypass Grafting. A double-blind, placebo-controlled, randomized trial.

NCT ID: NCT03046264 Active, not recruiting - Clinical trials for Coronary Heart Disease

Invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

MEASURE-cBP1
Start date: September 1, 2013
Phase: N/A
Study type: Observational

There is growing evidence that central blood pressure is a better predictor of hypertensive end-organ damage and cardiovascular outcome than routine brachial readings. The investigators aimed to evaluate the accuracy of a novel device for the non-invasive determination of central blood pressure based on automated oscillometric radial pulse wave analysis.

NCT ID: NCT03018561 Active, not recruiting - Clinical trials for Coronary Artery Disease

Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles

COGNEX
Start date: January 2011
Phase: N/A
Study type: Interventional

People with cardiovascular risk (CV) factors (obesity, diabetes, etc...) or established heart disease (such as coronary heart disease or chronic heart failure) often have cognitive dysfunction as compared to people without CV risk factors or heart disease. Among the mechanisms, a reduced cardiac output and cerebral blood flow in those people have been suggested. The aim of this study was to compare resting cognitive function, maximal cardiopulmonary function, cardiac output and cerebral hemodynamics during exercise in patients with metabolic syndrome, coronary heart disease, or heart failure vs. healthy subjects.