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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03443193 Active, not recruiting - Clinical trials for Coronary Heart Disease

Periodization of Exercise Training in Patients With Coronary Heart Disease.

PERIOD
Start date: December 16, 2015
Phase: N/A
Study type: Interventional

The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

NCT ID: NCT03433196 Active, not recruiting - Clinical trials for Hypercholesterolemia in Coronaory Heart Disease

Efficacy and Safety Study of the HS-25 Combination With Atorvastatin in Subjects With Hypercholesterolemia in Coronary Heart Diseases

HS-25-III-02
Start date: June 7, 2016
Phase: Phase 3
Study type: Interventional

To determine the efficacy of HS-25 (20mg) in reducing low density lipoprotein-cholesterol (LDL-C) levels after a 12-week period of treatment in combination with Atorvastatin in subjects with hypercholesterolemia and coronary heart diseases; To determine the safety of HS-25 (20mg) combination with Atorvastatin in subjects with hypercholesterolemia and coronary heart diseases

NCT ID: NCT03425305 Active, not recruiting - Heart Failure Clinical Trials

Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study

Start date: January 1998
Phase: N/A
Study type: Observational

Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial results. Estimation of this association may help to predict cardiovascular outcomes and may guide new treatment strategies. The hypothesis is that increased serum uric acid level is associated with a range of cardiovascular diseases.

NCT ID: NCT03417050 Active, not recruiting - Clinical trials for Coronary Artery Disease

Synergy Between PCI With TAXUS and Cardiac Surgery: SYNTAX Extended Survival

SYNTAXES
Start date: December 2016
Phase: N/A
Study type: Observational

An investigator-driven, retrospective study to compare long-term survival-data (10-year follow-up) of patients with coronary artery disease (CAD), previously enrolled in the SYNTAX trial, who were randomized to percutaneous coronary intervention (PCI) using a paclitaxel (TAXUS) drug-eluting-stent (DES) or coronary artery bypass grafting (CABG).

NCT ID: NCT03409731 Active, not recruiting - Clinical trials for Coronary Artery Disease

Absorb GT1 Japan PMS

Start date: December 13, 2016
Phase: N/A
Study type: Interventional

The purpose of the Surveillance is to know the frequency and status of adverse device effects and adverse events in order to assure the safety of the new medical device, and to collect efficacy and safety information for evaluating clinical use results.

NCT ID: NCT03394339 Active, not recruiting - Stroke Clinical Trials

Meta-analysis of Fruit and Vegetable Sources and Cardiovascular Outcomes

Start date: April 1, 2017
Phase: N/A
Study type: Observational

Fruit and vegetables are a cornerstone of healthy dietary patterns and dietary guidelines worldwide. The supporting evidence, however, is largely derived from observational studies of protective associations with cardiovascular disease (CVD) in health-conscious populations or from randomized trials of the effect of specific fruit or vegetable derived nutrients on CVD risk factors. A growing body of literature has influenced a shift away from a focus on single nutrients to a focus on whole foods and dietary patterns. To what extent fruit and vegetables should contribute to dietary patterns for cardiovascular health and whether specific types of fruit or vegetables should be recommended is unclear. Although previous systematic reviews and meta-analyses have elucidated the association between the intake of total and some specific fruit and vegetables with cardiovascular outcomes, a comprehensive synthesis comparing the certainty of the evidence for the different types of fruit and vegetables in relation to a range of cardiovascular outcomes has yet to be completed. We propose to conduct a systematic review and meta-analysis of the available prospective cohort studies using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the association between different types of fruit and vegetables and different cardiovascular outcomes that include CVD, coronary heart disease [CHD], and stroke incidence and mortality.

NCT ID: NCT03383718 Active, not recruiting - Clinical trials for Ischemic Heart Disease

DSE vs. FFR in SCAD and BYSTANDER Lesions

DSE-vs-FFR
Start date: December 1, 2014
Phase: N/A
Study type: Observational

Enrollment: - Patients with stable coronary artery disease (SCAD) and moderate coronary artery stenoses (30-70 %) - Patients with acute myocardial infarction and moderate stenosis of non-culprit arteries (NCL; BYSTANDER LESION) Aims: - To assess the diagnostic accuracy of dobutamine stress echocardiography (DSE) and invasive fractional flow reserve (FFR) measurement - To assess the prognostic impact of reclassification by a mismatching negative test Hypothesis: - DSE and FFR have similar prognostic value in both clinical settings (SCAD and NCL) - Considering the strong negative predictive value of both DSE and FFR, one negative test is sufficiently enough to defer revascularisation, even in the case of mismatch

NCT ID: NCT03351738 Active, not recruiting - Clinical trials for Stable Coronary Heart Disease

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease

Start date: December 13, 2017
Phase: Phase 2
Study type: Interventional

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease

NCT ID: NCT03338335 Active, not recruiting - Clinical trials for Coronary Artery Disease

Ethnic Differences and the Ischemia/Bleeding Risk of DAPT Duration

Start date: March 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

this study is an individual patient level meta-analysis of randomized clinical trials, to evaluate the influence of ethnicity, to study whether the relative tradeoff between ischemia and bleeding is distinct by ethnicity.

NCT ID: NCT03338309 Active, not recruiting - Unstable Angina Clinical Trials

INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice, Prospective, Multicenter Registry

INTERPRET
Start date: November 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The current study sought to evaluate the clinical relevance of iFR-guided strategy in real world clinical practice using unrestricted study population from stable angina to acute coronary syndrome including acute ST-segment elevation myocardial infarction. Previous abundant historical data of FFR-guided strategy will be also included as historical control to validate the iFR-guided strategy.