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Ischemic Heart Disease clinical trials

View clinical trials related to Ischemic Heart Disease.

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NCT ID: NCT03531151 Recruiting - Heart Failure Clinical Trials

MRI of Myocardial Infarction

MRIMI
Start date: April 1, 2018
Phase:
Study type: Observational [Patient Registry]

Heart failure (HF) is an enormous health burden affecting approximately 5.1 million people in the US and is the cause of 250,000 deaths each year. Approximately 50% of HF is caused by myocardial ischemia and requires immediate restoration of coronary blood flow to the affected myocardium. However, the success of reperfusion is partly limited by intramyocardial hemorrhage, which is the deposition of intravascular material into the myocardium. Hemorrhagic reperfusion injury has high prevalence and patients have a much greater risk of adverse left ventricular remodeling, risk of fatal arrhythmia, impaired systolic function and are hospitalized at a greater rate. Recent magnetic resonance imaging techniques have improved assessment of reperfusion injury, however, the association between MRI contrasts and reperfusion injury is highly unclear, and lacks specificity to IMH. Improved imaging of IMH and accurate knowledge about its spatial and temporal evolution may be essential for delivery of optimal medical therapy in patients and critical to identify patients most at risk for adverse ventricular remodeling. The overall goal is to investigate the magnetic properties of hemorrhage and develop MRI techniques with improved specificity to hemorrhage. New MRI techniques permit noninvasive assessment of the magnetic susceptibility of tissues and can target tissue iron. Therefore, we hypothesize that MRI imaging of myocardial magnetic susceptibility can map hemorrhagic myocardium. We will perform a longitudinal observational study in patients after reperfusion injury to validate these methods, compare them with conventional MR contrasts and develop MR methods for imaging live animals.

NCT ID: NCT03523286 Not yet recruiting - Clinical trials for Ischemic Heart Disease

Real-time Automated Program for IDentification of VT Origin

RAPIDVTPilot
Start date: June 2018
Phase: N/A
Study type: Interventional

RAPID-VT Pilot is a single centre prospective cohort pilot study to assess the feasibility, safety and efficacy of catheter ablation of ventricular tachycardia (VT) guided by a novel real-time software to localize the origin of VT during the ablation procedure.

NCT ID: NCT03501303 Recruiting - Clinical trials for Ischemic Heart Disease

A Clinical Trial on No-touch Vein Graft (NT-graft) in Coronary Surgery

SWEDEGRAFT
Start date: April 20, 2018
Phase: N/A
Study type: Interventional

The primary objective in this study is to investigate if vein grafts harvested and implanted with the non-touch technique are superior to conventional vein graft technique with respect to mid-term patency, in patients undergoing CABG surgery.

NCT ID: NCT03474835 Enrolling by invitation - Clinical trials for Ischemic Heart Disease

Ischemic Heart Disease in Male With Prostate Adenocarcinoma

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The purpose of the study: to increase the efficiency of diagnosis, treatment and prediction of the course of coronary heart disease in patients with adenocarcinoma of the prostate gland, depending on the hormonal status by determining the cardiovascular risk factors, factors of angiogenesis, structural and functional state of the heart, coronary vessels, kidney damage and their pharmacological correction.

NCT ID: NCT03471845 Recruiting - Clinical trials for Coronary Artery Disease

RESOLUTE ONYX China Single Arm Study

Start date: March 30, 2018
Phase: N/A
Study type: Interventional

It is a single arm clinical evaluation of safety and efficacy of the Medtronic Resolute Onyx™ zotarolimus-eluting coronary stent system in subjects who are eligible for percutaneous transluminal coronary angioplasty (PTCA) in de novo lesions amenable to treatment with Resolute Onyx™ Stent System in China.

NCT ID: NCT03466151 Recruiting - Clinical trials for Coronary Artery Disease

RESOLUTE ONYX China RCT Study

Start date: April 12, 2018
Phase: N/A
Study type: Interventional

It is a randomized controlled trial to evaluate the safety and efficacy of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in comparison with the Medtronic Resolute Integrity™ Zotarolimus-Eluting coronary stent system in the treatment of subjects eligible for percutaneous transluminal coronary angioplasty (PTCA) in China.

NCT ID: NCT03446313 Not yet recruiting - Clinical trials for Cardiovascular Diseases

Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart)

Mobile4Heart
Start date: March 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether using a mobile app increases adherence to a heart healthy prescription after discharge from a cardiac rehab program.

NCT ID: NCT03438500 Recruiting - Clinical trials for Coronary Artery Disease

Cardiac Shock Wave Treatment in Patients With Reduced Coronary Flow Reserve

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the feasibility of Cardiac Shock Wave Treatment in patients with anginal chest pain and evidence of abnormal myocardial perfusion under stress in the absence of significant stenoses of the epicardial coronary arteries.

NCT ID: NCT03411369 Completed - Clinical trials for Ischemic Heart Disease

Creatine, D-Ribose, B1 Vitamin, and B6 Vitamin in Ischemic Heart Disease

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Recently, researchers have paid attention to the development of new products such as supplements food and nutraceuticals for identify and develop integrative therapies to be used in cardiovascular disease. As suggested by literature, some nutritional components (creatine, ribose) can enhance the fundamental energy levels for the functioning of the heart muscle and can enhance the body's antioxidant capacity through the reduction in free radicals activity, one of the main pathogenic mechanisms of these diseases. In this context, the investigators have developed a research with the principal purpose to establish whether a supplement of creatine and ribose can improve the total work capacity during exercise in a population of patients with known ischemic heart disease.

NCT ID: NCT03409731 Active, not recruiting - Clinical trials for Coronary Artery Disease

Absorb GT1 Japan PMS

Start date: December 13, 2016
Phase: N/A
Study type: Interventional

The purpose of the Surveillance is to know the frequency and status of adverse device effects and adverse events in order to assure the safety of the new medical device, and to collect efficacy and safety information for evaluating clinical use results.