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Coronary Heart Disease clinical trials

View clinical trials related to Coronary Heart Disease.

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NCT ID: NCT03567408 Not yet recruiting - Clinical trials for Coronary Heart Disease

Clinical Study of Bivalirudin for Percutaneous Coronary Intervention (PCI)

Start date: July 30, 2018
Phase: Phase 2
Study type: Interventional

Bivalirudin is widely used as an anticoagulant to reduce the risk of bleeding in PCI perioperative period. Additionally, 15.7%-32.7% patients have diabetes mellitus who undergo percutaneous coronary interventions (PCI), so bivalirudin was used to anticoagulate in these patients to evaluate its safety and efficacy.

NCT ID: NCT03555734 Active, not recruiting - Obesity Clinical Trials

Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases

Start date: November 21, 2017
Phase:
Study type: Observational

The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding dietary pulses. To update the recommendations, the Diabetes and Nutrition Study Group (DNSG) of the EASD commissioned an umbrella review and updated systematic review and meta-analysis using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to summarize the available evidence from prospective cohort studies of the association between dietary pulses/legumes and cardiometabolic disease outcomes (incident cardiovascular diseases, diabetes, hypertension and overweight/obesity).

NCT ID: NCT03542370 Active, not recruiting - Diabetes Clinical Trials

Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk

Start date: September 1, 2017
Phase:
Study type: Observational

The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and vegetables, low-fat or non-fat dairy, limiting saturated fat intake and usually also recommends limiting sodium intake. To update the recommendations, the Diabetes and Nutrition Study Group (DNSG) of the EASD commissioned an umbrella review of systematic reviews and meta-analyses using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to summarize the available evidence from recent systematic reviews and meta-analyses of prospective cohort studies and randomized controlled trials of the relationship between the DASH dietary pattern and cardiometabolic risk.

NCT ID: NCT03529916 Recruiting - Clinical trials for Coronary Heart Disease

Endothelial Cell Gene Networks of CVD

Start date: May 21, 2018
Phase:
Study type: Observational

The objective of this study is to identify relevant signature gene networks of cardiovascular disease in endothelial cells derived from circulating endothelial progenitor cells of individuals with established cardiovascular disease (CVD).

NCT ID: NCT03511885 Recruiting - Clinical trials for Cardiovascular Diseases

EUROASPIRE V Survey on Cardiovascular Disease Prevention and Diabetes

EUROASPIRE
Start date: May 1, 2016
Phase:
Study type: Observational

EUROASPIRE is a multicentre European study in coronary patients and individuals at high risk of developing cardiovascular disease (CVD), describing their management through lifestyle and use of drug therapies and providing an objective assessment of clinical implementation of current scientific knowledge. Four EUROASPIRE surveys have been carried out by the European Society of Cardiology so far: EUROASPIRE I in 1995-1997 in nine countries, EUROASPIRE II in 1999- 2000 in 15 countries, EUROASPIRE III in 2006-2009 in 22 countries and EUROASPIRE IV in 2012-2015 in 26 countries. The results showed a wide gap between the recommendations and clinical practice with many patients not achieving the lifestyle and medical risk factors goals for CVD prevention. The fifth EUROASPIRE survey is planned for 2016-2018 to determine in hospital coronary patients and apparently healthy individuals in primary care at high risk of developing cardiovascular disease whether the European and national guidelines on cardiovascular disease prevention have been followed and if the practice of preventive cardiology in EUROASPIRE IV has improved by comparison with those centres which took part in EUROASPIRE I, II, III and IV. This survey will also incorporate an assessment of dysglycaemia and kidney function in all patients. The main outcome measures will be the proportions of coronary and high cardiovascular risk patients achieving the lifestyle, risk factor and therapeutic targets for cardiovascular disease prevention. The data collection will be based on a review of patient medical records and a patient interview and examination at least 6 months and at most 3 years after recruiting event. All countries which participated in the first three surveys will be invited to take part in EUROASPIRE V. This fifth survey will give a unique picture of preventive action by cardiologists and primary care physicians looking after patients with coronary disease and individuals at high CVD risk.

NCT ID: NCT03478332 Recruiting - Clinical trials for Coronary Heart Disease

Effects of Yangxinshi Pills on the Exercise Tolerance of the Patients With Coronary Heart Disease

Start date: June 1, 2017
Phase: Phase 2
Study type: Interventional

Compared with conventional treatment of the coronary heart disease,the aim of the research is to find out if the addition of Yangxinshi pills on the basis of conventional treatment can improve exercise tolerance of patients with coronary heart disease, improve quality of life or restore social function and mental health

NCT ID: NCT03462277 Recruiting - Clinical trials for Coronary Heart Disease

DNA Methylation and Hydroxymethylation Levels in Patients With Coronary Heart Disease

Start date: January 1, 2018
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this trial is to investigate the relationship between DNA methylation and hydroxymethylation and the expression of DNMTs, TET family gen and coronary heart disease.

NCT ID: NCT03461367 Not yet recruiting - Clinical trials for Coronary Heart Disease

CTO Registry From Insight of IVUS in Fuwai Hospital

FWCTO
Start date: May 1, 2018
Phase: N/A
Study type: Observational [Patient Registry]

To evaluate the long-term outcome of chronic total occlusion (CTO) patients underwent contemporary percutaneous coronary intervention (PCI) techniques, we design this single-center, large-sample, prospective registry with five-year clinical follow-up, based on the intravascular ultrasound (IVUS) finding.

NCT ID: NCT03443193 Active, not recruiting - Clinical trials for Coronary Heart Disease

Periodization of Exercise Training in Patients With Coronary Heart Disease.

PERIOD
Start date: December 16, 2015
Phase: N/A
Study type: Interventional

The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

NCT ID: NCT03437616 Enrolling by invitation - Clinical trials for Coronary Heart Disease

Cardiovascular Rehabilitation - Effectiveness of the Tulppa Program

Start date: February 2018
Phase: N/A
Study type: Interventional

This study investigates the effectiveness of a Finnish Tulppa outpatient rehabilitation program. Tulppa is a group-based secondary prevention program for patients with vascular diseases. The program is developed by the Finnish Heart Association. The intervention is implemented at the local primary health care centers in 12 health districts in Finland. A longitudinal controlled study is used to investigate the effects of the intervention on participants' level of cardiovascular risk factors (e.g. lipids, blood pressure, body mass index), functional capacity (e.g. 6 minute walk test), life style as well as psychosocial factors (e.g. smoking, diet, physical activity, health-related quality of life and depression). The data will be collected at baseline (i.e. before the intervention), and 6 and 12 months after the intervention started. The participants (n = 300) are patients diagnosed with coronary heart disease. The study group (n = 150) is recruited from participants of Tulppa rehabilitation in two health care districts (Pirkanmaa and Southern Karelia). The control group (n = 150) is recruited from two health care districts (Turku and Hyvinkää) that do not provide Tulppa rehabilitation.