Clinical Trials Logo

Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

Filter by:

NCT ID: NCT03793049 Not yet recruiting - Clinical trials for Coronary Artery Disease

Repeatability and Reproducibility of the CADence™System

SEQUEL
Start date: January 12, 2019
Phase:
Study type: Observational

This study is designed as a prospective study to capture data for evaluating the repeatability and reproducibility of the CADence™ System. The study will be conducted at 3 different study sites using 6 CADence™ systems. Each subject will be tested 4 separate times by 2 different operators at each site and will be tested at all 3 site locations in order to accomplish this evaluation. The study will enroll a total of at least 24 CADence positive patients and at least 24 CADence negative patients.

NCT ID: NCT03791788 Recruiting - Clinical trials for Ischemic Heart Disease

Multicenter Registry for Angiography-Derived Quantitative Flow Ratio

QFRRegistry
Start date: November 30, 2018
Phase:
Study type: Observational

1. to investigate the feasibility and diagnostic performance of contrast quantitative flow ratio (QFR) for identifying the functional significance of intermediate degree stenotic lesions in all-comer patients with coronary artery disease (CAD) including presentation of acute myocardial infarction (AMI) with non-culprit lesion. 2. to compare the changes of contrast QFR and fractional flow reserve (FFR) according to severity of percent diameter stenosis (%DS)

NCT ID: NCT03791320 Recruiting - Clinical trials for Coronary Artery Disease

Fast Assessment of STenosis Severity- FASTII Study

FASTII
Start date: October 15, 2018
Phase:
Study type: Observational

The Multicenter FAST (Fast Assessment of STenosis severity) study is a prospective observational multicenter study designed to evaluate the diagnostic accuracy of offline 3D-QCA based FFR, using CAAS Workstation (Pie Medical Imaging, Maastricht, the Netherlands) in identifying hemodynamically significant coronary artery disease with pressure wire-based FFR (≤0.80) as the reference standard.

NCT ID: NCT03789916 Recruiting - Clinical trials for Coronary Artery Disease

SAPT Versus DAPT in Incomplete Revascularization After CABG

SDAT-IRC
Start date: January 2, 2019
Phase: Phase 3
Study type: Interventional

The study aims to compare the efficacy of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients with incomplete revascularization after coronary artery bypass graft surgery (CABG). Before hospital discharge, patients will be 1:1 randomized to SAPT (acetylsalicylic acid 100 mg/die) or DAPT (acetylsalicylic acid 100 mg/die + ticagrelor 90 mg bis in die). DAPT will be continued for 12 months, and ticagrelor will be withdrawn thereafter. Primary endpoint is the evaluation of cardiac-related mortality at 5 years from hospital discharge.

NCT ID: NCT03788512 Not yet recruiting - Clinical trials for Coexistence of Cerebral and Coronary Atherosclerosis

Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry

CoCCA
Start date: December 30, 2018
Phase:
Study type: Observational [Patient Registry]

Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is a single-center observational registry of patients hospitalized for acute ischemic cerebrovascular disease (AICVD) with atherosclerotic changes in both cerebral and coronary arteries. This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.

NCT ID: NCT03788369 Not yet recruiting - Coronary Stenosis Clinical Trials

Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization

HCR registry
Start date: January 15, 2019
Phase:
Study type: Observational

This study evaluated the effectiveness and safety of Hybrid Coronary Revascularization in real-world practice.

NCT ID: NCT03787797 Recruiting - Clinical trials for Acute Coronary Syndrome

Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients

EPIC-ACS
Start date: December 6, 2018
Phase:
Study type: Observational

Epicardial adipose tissue (EAT) is a visceral adipose tissue that surrounds the heart and the coronary arteries. It is metabolically active, secreting pro- and anti-inflammatory mediators and cytokines. With increasing EAT volume, inflammatory activity increasing, which suggests that EAT may locally influence atherosclerosis development in the coronary artery tree. The amount of EAT is associated with cardiovascular disease risk factors as well as presence and progression of subclinical atherosclerosis. Likewise, EAT volume is increased in patient with prevalent and incident coronary artery disease manifestation. In the setting of acute coronary syndrome, EAT was found to be associated with the TIMI risk score and Syntax II score. While CT imaging of the heart is the gold standard for EAT quantification, transthoracic echocardiography allows for a quick and reliable assessment of EAT thickness, as has been used in research studies and may qualify for routine EAT assessment in clinical routine.However, currently data on how quantification of EAT in clinical routine may impact patient management is lacking. We aim to investigate, whether quantification of EAT thickness via transthoracic echocardiography enables improved risk stratification in patients presenting with acute chest pain to the emergency department.

NCT ID: NCT03786965 Recruiting - Clinical trials for Ischemic Heart Disease

Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.

MPO-CSP
Start date: December 20, 2018
Phase: N/A
Study type: Interventional

The main objection is to investigate molecular biology of myocardial damage during cardiac surgery procedures.

NCT ID: NCT03786939 Recruiting - Clinical trials for Ischemic Heart Disease

Evaluation of Outcomes of Coronary Artery Bypass Grafting.

EOCABG
Start date: December 20, 2018
Phase: N/A
Study type: Interventional

Evaluation of outcomes of coronary artery bypass grafting.

NCT ID: NCT03782688 Not yet recruiting - Clinical trials for Stable Coronary Artery Disease

Precise Percutaneous Coronary Intervention Plan (P3) Study

P3
Start date: December 17, 2018
Phase:
Study type: Observational [Patient Registry]

The PRECISE PERCUTANEOUS CORONARY INTERVENTION (PCI) PLAN STUDY is an investigator-initiated, international and multicenter study of patients with an indication for PCI aiming at assessing the agreement and accuracy of the HeartFlow Planner with invasive fractional flow reserve (FFR) as a reference.