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NCT ID: NCT06330402 Recruiting - Healthy Clinical Trials

Exploration of Gait Biomechanics and Pain

Start date: September 26, 2023
Phase: N/A
Study type: Interventional

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental knee pain. The main questions it aims to answer are: - How do gait patterns change during painful walking? - Can pain sensitivity testing and gait biomechanics predict experimental knee pain intensity? Participants will receive two knee injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition).

NCT ID: NCT06329076 Recruiting - Healthy Clinical Trials

Losartan Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study

Start date: March 5, 2024
Phase: N/A
Study type: Interventional

The main aim of the present study is to investigate the effects of orally administered losartan on the perception of time-to-collision of threatening and non-threatening stimuli by combining a validated looming fear eye-tracking paradigm with a randomized between-subject placebo-controlled pharmacological trial design.

NCT ID: NCT06329063 Recruiting - Healthy Clinical Trials

Oral Vasopressin Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study

Start date: March 5, 2024
Phase: N/A
Study type: Interventional

The main aim of the present study is to investigate the effects of orally administered vasopressin (AVP) on the perception of time-to-collision of threatening and non-threatening stimuli by combining a validated looming fear eye-tracking paradigm with a randomized between-subject placebo-controlled pharmacological trial design.

NCT ID: NCT06329050 Recruiting - Healthy Clinical Trials

The Effects of Losartan on Attention Control: An Eye-tracking Study

Start date: March 5, 2024
Phase: N/A
Study type: Interventional

The main aim of the present study is to investigate the effects of orally administered Losartan on bottom-up and top-down attentional control to socio-emotional stimuli by combining a validated saccade/antisaccade eye-tracking paradigm with a randomized between-subject placebo-controlled pharmacological trial design.

NCT ID: NCT06329037 Recruiting - Healthy Clinical Trials

The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study

Start date: March 5, 2024
Phase: N/A
Study type: Interventional

The main aim of the present study is to investigate the effects of orally administered vasopressin (AVP) on bottom-up and top-down attentional control to socio-emotional stimuli by combining a validated saccade/antisaccade eye-tracking paradigm with a randomized between-subject placebo-controlled pharmacological trial design.

NCT ID: NCT06327256 Recruiting - Healthy Clinical Trials

A Study in Healthy People to Test How Well Different Doses of BI 3000202 Are Tolerated and How They Affect the Way the Body Handles Midazolam

Start date: March 28, 2024
Phase: Phase 1
Study type: Interventional

The aim of this trial is to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) following multiple rising doses of BI 3000202 and to investigate the effect of BI 3000202 on the metabolism of midazolam.

NCT ID: NCT06327087 Recruiting - Healthy Clinical Trials

Appetite and Dietary Intake Across the Menstrual Cycle

Start date: June 1, 2022
Phase:
Study type: Observational

Lay language summary: Women are younger and menstruating about monthly ("pre-menopausal") often have fluctuations in the food they eat ("dietary intake") across the menstrual cycle. However, relationships between food intake and appetite, metabolism, body composition (i.e., the proportion of muscle and fat), physical activity and premenstrual symptoms have not been reported. This study will measure appetite and food intake in laboratory and usual life settings in healthy pre-menopausal women in two hormonally different parts of the menstrual cycle. Data on ovarian hormones, metabolism, body composition, physical activity and premenstrual symptoms will also be collected to assess their potential relationship with food intake.

NCT ID: NCT06325150 Recruiting - Healthy Clinical Trials

The Impact of Light Exposure on Cognitive Function in Classrooms

Start date: May 16, 2024
Phase: Phase 1
Study type: Interventional

Humans are constantly exposed to a variety of light types, created naturally or through artificial means. Light exposure captured by the eyes impacts many physiological functions in humans, including but not limited to cognitive output, fatigue levels, and mood regulation. The level of impact on cognitive learning from different types of light on undergraduate adult students remains unclear.

NCT ID: NCT06318390 Recruiting - Healthy Clinical Trials

The Impact of KETO5 XOGenius Beverage on Markers of Physiological and Neurocognitive Health

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The primary objectives of this application are to 1) investigate the effect of increased daily consumption of the Keto5 XOGenius beverage on outcomes associated with elevated risk for various neurocognitive and pathophysiological conditions/diseases. And 2) to investigate the effect of daily consumption of the Keto5 XOGenius beverage on the following variables: waist circumference, body weight, and body mass index (BMI).

NCT ID: NCT06318377 Recruiting - Healthy Clinical Trials

Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The overall research objective of this proposal is to determine the impact of increased daily peanut consumption on indices of neurocognitive and physiological health in BL individuals