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NCT ID: NCT05857449 Completed - Healthy Clinical Trials

An Exploratory Study of LPM3480392 at Different Infusion Rates in Chinese Healthy Subjects

Start date: November 8, 2021
Phase: Phase 1
Study type: Interventional

This study evaluated the safety, tolerability and PK/PD characteristics of LPM3480392 injection by intravenous infusion at different rates in healthy subjects.The experiment was divided into Part A and Part B. Part A is a open label ,three cycle , fixed sequence dosing study .Twelve healthy male subjects were planned to be enrolled, and the same dose (X1mg)of LPM3480392 injection was intravenously injected at different infusion times in different drug administration cycles. Part B is an open label ,two cycle , fixed sequence dosing study .Ten healthy male subjects (subjects not enrolled in Part A) were given LPM3480392 injection in 2 minutes , each subject was given X2mg at the first cycle and X3mg at the second cycle .

NCT ID: NCT05855187 Completed - Healthy Clinical Trials

Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)

Start date: November 15, 2022
Phase: Phase 1
Study type: Interventional

Comparative, Randomized, Single Dose, Two-way Crossover Bioequivalence Study to determine the bioequivalence of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)

NCT ID: NCT05854771 Completed - Healthy Clinical Trials

Effects Of Yoga Before vs After Eccentric Exercise On Delayed Onset Muscle Soreness

Start date: October 28, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effects of pre and post-exercise yoga after eccentric exercise on delayed onset muscle soreness in healthy adults. The main question it aims to answer is whether there will be a difference in the effects of pre and post-exercise yoga in reducing delayed muscle soreness. The participants will be divided into two groups; group A and group B. Group A will perform single bout of yoga before the eccentric exercise and Group B will perform single bout of yoga after eccentric exercise.

NCT ID: NCT05853341 Completed - Healthy Clinical Trials

Rivastigmine Bioequivalence Trial With Multiple Application of Transdermal Patches (13.3mg/24h)

Start date: May 2, 2023
Phase: Phase 1
Study type: Interventional

The present clinical trial will be conducted in order to compare the bioavailability of rivastigmine and to assess bioequivalence at steady-state of the Test product RID-TDS 13.3 mg/24 h (Luye Pharma AG, Germany) and the marketed Reference product Exelon® 13.3 mg/24 h transdermales Pflaster (Novartis Pharma GmbH, Germany) after multiple patch applications. Each of both treatments will last for 11 days with a washout period of 14 days between the treatments.

NCT ID: NCT05850767 Completed - Healthy Clinical Trials

The Effect of Sleep Deprivation on Passive and Active Functions and Distance Modulation of the Vestibulo-Ocular Reflex

Start date: May 19, 2022
Phase: N/A
Study type: Interventional

The goal of this cross-over clinical trial is to evaluate the effect of 24 hours sleep deprivation on the Vestibulo-Ocular Reflex (VOR) in healthy participants. The main questions it aims to answer are: 1. The effect of sleep deprivation on vestibular function. 2. The difference between passive and active VOR function following sleep deprivation. 3. The vergence mediated modulation ability of the VOR following sleep deprivation. 4. The effect of sleep deprivation on behavioral VOR function. Participants will be tested before and after a normal night sleep and during 24 hours of sleep deprivation.

NCT ID: NCT05850429 Completed - Healthy Clinical Trials

BioDulse: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Healthy Adults

BioDulse
Start date: May 9, 2023
Phase: N/A
Study type: Interventional

Co-ingesting protein with carbohydrate is an effective way to improve postprandial glucose handling. The investigators have isolated and identified a bioactive protein extracted from seaweed. The investigators aim to explore how varying doses of seaweed protein influence postprandial glycaemia and insulinaemia in a healthy population.

NCT ID: NCT05843799 Completed - Healthy Clinical Trials

A Study to Evaluate the Safety and Tolerability of ILB-202

Start date: May 16, 2023
Phase: Phase 1
Study type: Interventional

This is a Phase I, Single-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of ILB-202 Administered Intravenously as Single Ascending Doses to Healthy Participants. Male or female subjects aged 18 to 50 years (inclusive) who fulfill the inclusion/exclusion criteria will be enrolled in this study.

NCT ID: NCT05841446 Completed - Healthy Clinical Trials

Bioequivalence Study of Apixaban Tablets in Healthy Chinese Subjects

Start date: March 2, 2021
Phase: Phase 1
Study type: Interventional

To evaluate the single-center, open, randomized, single-dose, two-cycle, two-sequence, cross-over bioequivalence of test preparation apixaban tablet 2.5mg and reference preparation 2.5mg in healthy adult subjects in fasting and fed state

NCT ID: NCT05841277 Completed - Healthy Clinical Trials

A Study of LY3819469 in Participants With Impaired and Normal Renal Function

Start date: April 25, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess the amount of study drug (LY3819469) that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to participants with normal renal function. The safety and tolerability of LY3819469 will also be evaluated in these participants. The study will last up to 17 weeks including screening period.

NCT ID: NCT05841238 Completed - Healthy Clinical Trials

A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese Participants

Start date: April 26, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate how much LY3502970 gets into the bloodstream and how long it takes the body to eliminate when administered orally as tablet and capsule formulations along with effect of food on LY3502970 in healthy overweight and obese participants. The study will also evaluate the safety and tolerability of LY3502970 in these participants. The study is conducted in two parts (part A and B) and will last up to 135 days including the screening period.