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NCT ID: NCT04652297 Not yet recruiting - Healthy Clinical Trials

Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Administration of HS-10356 in Healthy Volunteers

Start date: December 2020
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to assess the safety and tolerability of single and multiple oral administration of HS-10356 in healthy volunteers.

NCT ID: NCT04646304 Not yet recruiting - Healthy Clinical Trials

Motion Capture as a Tool for the Assessment of Laparoscopic Performance

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to 1) identify motion capture variables that can be used to differentiate surgical experience level and 2) evaluate if these variables can be used in a surgical education setting to improve resident performance.

NCT ID: NCT04629287 Not yet recruiting - Healthy Clinical Trials

Safety,Tolerability, and Pharmacokinetic of KPCXM18 for Injection

Start date: November 2020
Phase: Phase 1
Study type: Interventional

to assess the safety,Tolerability, and pharmacokinetic of KPCXM18 for injection in healthy subjects

NCT ID: NCT04616261 Not yet recruiting - Healthy Clinical Trials

Beta2-adrenergic System and Training

Start date: November 10, 2020
Phase: N/A
Study type: Interventional

This project aims to examine the trainability of the beta2-adrenergic system with respect to the individual performance response

NCT ID: NCT04615611 Not yet recruiting - Healthy Clinical Trials

Physiologic Performance Response to Salbutamol

Start date: November 7, 2020
Phase: N/A
Study type: Interventional

This project aims to investigate the individual physiological response to beta2-adrenergic stimulation with salbutamol on performance-related outcomes

NCT ID: NCT04567797 Not yet recruiting - Healthy Clinical Trials

Assessing the Efficacy of Passive Exoskeletons for Construction Work: Lab-Based Study

Start date: October 2020
Phase: N/A
Study type: Interventional

This project aims to assess the effectiveness and acceptability of four types of commercial Back support exoskeletons (BSEs) for concrete work tasks. BSEs are external wearable devices designed to reduce physical demands on the back by providing assistive moments to body joints to support muscles. There is considerable evidence to suggest such exoskeletons reduce the risks of back injuries for workers performing repetitive tasks. However, since the effects of using BSEs in concrete work tasks are still unknown, evidence-based information regarding effectiveness, productivity impact, and safety risks is required to help industries adopt BSEs as an ergonomic intervention.

NCT ID: NCT04524052 Not yet recruiting - Healthy Clinical Trials

To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX2003 Against COVID-19

Start date: August 2020
Phase: Phase 1
Study type: Interventional

This study is to assess the safety, tolerability, pharmacodynamics, and pharmacokinetics of Niclosamide (DWRX2003) following escalating doses of DWRX2003 administered as an intramuscular injection in healthy volunteers.

NCT ID: NCT04488887 Not yet recruiting - Healthy Clinical Trials

OCTA Metrics Repeatability and Reproducibility in Different Disorders

Start date: August 1, 2020
Phase:
Study type: Observational

Retinal imaging is a corner stone in diagnosis of most retinal disorders. Standard imaging techniques e.g. fluorescein angiography and color fundus photography have a lot of limitations including limited resolution, invasive nature in cases of fluorescein angiography, and inability to segment the retina, accordingly, and only 2D image is provided. Optical coherence tomography angiography (OCTA) is a recent noninvasive imaging technique that allows for volumetric visualization of eye vasculature. OCTA has shown promise in better elucidating the pathophysiology of several retinal vascular diseases. Swept-source OCTA uses long wavelength ̰ 1,050nm, which can penetrate through deeper layers of the eye and can traverse opacities of media such as cataracts, hemorrhages and vitreous opacities. Optical coherence tomographic angiograms can further be manually or automatically segmented with preprogrammed software to highlight individual layers of the retina, optic nerve head choriocapillaris, and choroid. The user can either analyze en face images extending from the inner limiting membrane to choroid or use automated views to locate a vascular or structural lesion within the retina. Different quantitative metrics has been extracted from enface OCTA images including vessel density, FAZ area, choriocapillaries flow deficit, intercapillary area and fractal dimension. These metrics are helpful in evaluation the retinal perfusion and used by physicians to assess various retinal vascular disorders. Although some previous literatures had discussed the repeatability of OCTA metrics, however, comprehensive evaluation of widely used metrics in various retinal condition has not be done. Additionally, recent data suggest that various methods of calculation of these metrics my yield final different results of the same metric.

NCT ID: NCT04415996 Not yet recruiting - Healthy Clinical Trials

L3/L4 High Velocity Low Amplitude Technique Influence On Baropodometric Pressures In Healthy Young Adults

Start date: September 2024
Phase: N/A
Study type: Interventional

In this double-blinded study, the objective is to determine the effects of bilateral High Velocity Low Amplitude (HVLA) technique on L3/L4 joint in baropodometric pressures in 60 healthy young adults.

NCT ID: NCT04399993 Not yet recruiting - Healthy Clinical Trials

Effect of Osteopathic Manual Techniques on the Diaphragm Muscle and Its Repercussions

Start date: September 2024
Phase: N/A
Study type: Interventional

Determining the effects of an intervention plan on the diaphragm related to the center of gravity and range of motion in the lumbar spine (static and dynamic) in healthy individuals is an area that lacks evidence and proper studies. Has such, the investigators consider this a interesting topic to study, therefore it is intended to improve the knowledge on this area.