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NCT ID: NCT05471206 Terminated - Healthy Clinical Trials

Evaluation of Gastrointestinal pH and Motility After the Consumption of Milk

ROVER
Start date: November 24, 2022
Phase: N/A
Study type: Interventional

This pilot study is designed as a monocentric, open label, interventional, parallel arms, controlled clinical trial. The aim of the study is to assess the gastrointestinal pH and motility after the consumption of milk. The clinical study is categorized as an interventional research involving the human person with low risks and constraints (RIPH 2) and which does not assess a health product. The milk and medical device used in this clinical study are both authorized and already commercialized in France.

NCT ID: NCT05423106 Terminated - Healthy Clinical Trials

A Single and Multiple Ascending Dose Study of JNJ-64457744

Start date: July 4, 2022
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of: single ascending dose (SAD) and multiple ascending dose (MAD) administration of JNJ-64457744, administered to healthy adult participants (Part 1 and Part 3), including a cohort of Asian participants (Part 1); and after single dose administration of JNJ-64457744 to chronic hepatitis B (CHB) participants who are virologically suppressed on nucleos(t)ide analog (NA) treatment (tenofovir disoproxil fumarate [TDF], tenofovir alafenamide [TAF], or entecavir [ETV]) (Part 2).

NCT ID: NCT05271656 Terminated - Healthy Clinical Trials

Evaluation of C-Scan Capsule in Identifying Subjects With Elevated Risk of Colon Polyps

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

The main objective of the study is to determine the ability of the C-Scan system to identify subjects who are at elevated risk for colon polyps. This will be evaluated by comparing the C-Scan data to colonoscopy data. The C-Scan procedure is therefore performed before the colonoscopy procedure, in order to compare these tests and evaluate the C-Scan system's effectiveness. During the C-scan procedure, Subjects will be asked to come for an appointment in a clinic, during this appointment, the C-Scan Track will be placed on the participant's back. The participant will then be asked to swallow the C-Scan capsule whereafter they are free to continue their routine. Participants will start intake of fiber pills 5 days, and contrast agent 48 hours prior to C-Scan capsule ingestion and will continue intake up to the capsule's natural excretion. A standard colonoscopy procedure will be performed within 60 days following C-Scan Cap ingestion.

NCT ID: NCT05254613 Terminated - Healthy Clinical Trials

A Study of Single and Multiple SC Doses of ALXN1830 in Healthy Adult Participants

Start date: November 12, 2019
Phase: Phase 1
Study type: Interventional

This study will evaluate the effects of single ascending doses (SAD) and multiple ascending doses (MAD) of ALXN1830 administered subcutaneously (SC) to healthy adult participants.

NCT ID: NCT05254340 Terminated - Healthy Clinical Trials

Healthy Volunteer Short Chain Fatty Acid Study

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the production of short chain fatty acids (fatty acids are part of your diet) in stool through the measurement of fecal inulin after a one-time ingestion of 10-gram dose of inulin among healthy adult volunteers.

NCT ID: NCT05205447 Terminated - Healthy Clinical Trials

Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants

Start date: January 5, 2022
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to learn about how itraconazole and carbamazepine affect the levels of LY3410738 in the blood stream of healthy participants. Participation could last up to 75 days.

NCT ID: NCT05162131 Terminated - Healthy Clinical Trials

Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in Chinese Healthy Volunteers

Start date: December 25, 2021
Phase: Phase 1
Study type: Interventional

This is a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose, sequential group study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PB2452 (Bentracimab) with and without ticagrelor pretreatment when administered to Chinese healthy male and female subjects. Up to 6 dose levels will be evaluated. This study will have 5 cohorts and a total of 40 subjects with 8 healthy subjects per cohort. Cohort 1 will be split into 3 parts, Cohort 1-a, 1-b and 1-c. The starting dose of PB2452 will be 100 mg and the planned doses for subsequent parts or cohorts are 300, 1000, 3000, 9000, and 18000 mg.

NCT ID: NCT05083078 Terminated - Healthy Clinical Trials

A Study of Guselkumab and Risankizumab in Healthy Participants and Participants With Psoriatic Arthritis

Start date: November 4, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the tissue distribution of guselkumab and risankizumab in healthy participants (Part 1) and psoriatic arthritis (PsA) participants (Part 2 and Part 3).

NCT ID: NCT05034913 Terminated - Healthy Clinical Trials

Digital Photography to Estimate Anthropometric Measurements in Children

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to see if photos taken from home can accurately let physicians know the height, abdominal circumference, and wrist circumference of children, and how these measurements relate to in-person measurements.

NCT ID: NCT04994899 Terminated - Healthy Clinical Trials

Aiberry AI Mental Health Screening Platform

Start date: September 22, 2022
Phase:
Study type: Observational

Aiberry is creating a multi-modal artificial intelligence (AI) platform that analyzes facial, audio and text features to screen for mental illness. This multicenter study will be used to collect data to validate the platform's ability to detect depression and anxiety in a diverse patient population.