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Healthy clinical trials

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NCT ID: NCT05945888 Completed - Healthy Clinical Trials

A Study in Healthy Men to Test How Different Doses of BI 3000202 Are Tolerated and How Food Influences the Amount of BI 3000202 in the Blood

Start date: July 25, 2023
Phase: Phase 1
Study type: Interventional

The single rising dose (SRD) part of the trial investigates safety, tolerability, and pharmacokinetics of BI 3000202. The food effect (FE) part is conducted to assess the effect of food on the relative bioavailability of the BI 3000202 formulation.

NCT ID: NCT05941247 Completed - Healthy Clinical Trials

A Study to Evaluate the Effects of Single and Multiple Doses of Hemay005 Tablets in Health Caucasian Adult Volunteers

Start date: July 17, 2023
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the safety and tolerability of single and multiple oral doses of Hemay005 tablets in healthy Caucasian adult volunteers.

NCT ID: NCT05940883 Completed - Healthy Clinical Trials

A Study to Evaluate the Pharmacokinetics,Safety and Tolerability of Y-2 Sublingual Tablet in Healthy Adult Subjects

Start date: September 6, 2023
Phase: Phase 1
Study type: Interventional

This study will assess the safety, tolerability and pharmacokinetics(PK) of Y-2 sublingual tablet in healthy adult subjects.

NCT ID: NCT05936138 Completed - Healthy Clinical Trials

A Study of LY3502970 in Participants With Normal and Impaired Renal Function

Start date: July 13, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess the amount of study drug (LY3502970) that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to participants with normal renal function. The safety and tolerability of LY3502970 will also be evaluated in these participants. The study will last up to 6 weeks including screening period.

NCT ID: NCT05934955 Completed - Healthy Clinical Trials

A Study in Healthy Men to Test How Well Different Doses of BI 1839100 Are Tolerated (1490-0003)

Start date: July 13, 2023
Phase: Phase 1
Study type: Interventional

The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 1839100 in healthy male subjects following oral administration of single rising doses.

NCT ID: NCT05933447 Completed - Healthy Clinical Trials

Thorough QT Study to Evaluate the Effect of Rodatristat Ethyl, Rodatristat and Its Major Metabolites on the Heart

Start date: May 12, 2023
Phase: Phase 1
Study type: Interventional

To evaluate whether Rodatristat Ethyl prolongs the QTc interval when orally administered to healthy volunteers.

NCT ID: NCT05932446 Completed - Healthy Clinical Trials

A Study to Compare Two Formulations of LY3819469 in Healthy Participants

Start date: June 30, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess two formulations of LY3819469 based on the amount that gets into the blood stream and how long it takes the body to get rid of it, when given to healthy participants. The information about any adverse effects experienced will be collected and the tolerability of LY3819469 will also be evaluated. Screening is required within 28 days prior to the enrolment. For each participant, the total duration of the clinical trial will be about 17 weeks including screening and follow-up periods.

NCT ID: NCT05931237 Completed - Healthy Clinical Trials

Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults

Start date: September 9, 2021
Phase: N/A
Study type: Interventional

Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability. The objective of this pilot study is to characterize the inter-individual variability associated with the interaction of (poly)phenols from cranberry and gut microbiota. The participants (n=39) of this study are healthy adults aged between 23 and 63 years old and consumed cranberry extract rich in (poly)phenols for 4 days. Plasma, urine and feces were collected to quantify gut microbial (poly)phenols metabolites and to profile the fecal microbiota.

NCT ID: NCT05930925 Completed - Healthy Clinical Trials

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Start date: June 12, 2023
Phase: Phase 1
Study type: Interventional

The purpose of the study is to understand how the study medicine ARV-471 is processed in the body of healthy males and females who do not have the potential to have children. This study is seeking for participants who: - are healthy males and females who do not have the potential to have children. - are 18 years of age or older. - weigh more than 110 pounds.

NCT ID: NCT05930808 Completed - Healthy Clinical Trials

Concor® Bioequivalence Study in Chinese Participants (Darmstadt-Nantong)

Start date: February 28, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess is the bioequivalence (BE) of Concor 5 milligram (mg) tablets manufactured by Merck/China Nantong (test product) and Concor 5 mg tablets manufactured by Merck/Germany Darmstadt (reference product) in Chinese healthy participants under fed or fasted condition.