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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT01085162 Withdrawn - Clinical trials for Coronary Artery Disease (CAD)

A Long-term Follow-up Study to Evaluate the Predictive Value of BMS747158 in Patients Suspected of Coronary Artery Disease (CAD)

Start date: March 2013
Phase: N/A
Study type: Observational

This long-term study will follow patients with known or suspected of having coronary artery disease (CAD) and have participated in present and future BMS747158 clinical studies. The purpose of this study is to evaluate the long-term predictive value associated with BMS747158 Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI).

NCT ID: NCT01073111 Withdrawn - Clinical trials for Coronary Artery Disease

Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents

ASSESS
Start date: April 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to compare coronary endothelium function in patients with a zotarolimus-eluting versus a sirolimus-eluting or a everolimus-eluting stents with optical coherence tomography, vasoconstriction in response to acetylcholine, and coronary biomarker level.

NCT ID: NCT01060306 Withdrawn - Clinical trials for Coronary Artery Disease

Optical Coherence Tomography Evaluation of a Biodegradable Polymer-based Drug-eluting Stent

PONTINA
Start date: January 2010
Phase:
Study type: Observational

PONTINA aims at assessing by optical coherence tomography the neointimal coverage of the biodegradable polymer-based Biolimus A9-eluting stent (Biomatrix stent) after full drug elution and polymer biodegradation (6 months), at one month after this time-point (7 months) and, as a comparator, of its bare metal stent counterpart (Gazelle stent) at 1 month after implantation.

NCT ID: NCT01016717 Withdrawn - Clinical trials for Coronary Artery Disease

Clopidogrel Proton-Pump Inhibitors Study

Start date: December 2012
Phase: Phase 4
Study type: Interventional

To find out the impact of two different proton-pump inhibitors (PPIs) (Omeprazole and Pantoprazole) on platelet function in patients with stable coronary artery disease (CAD) on clopidogrel therapy.

NCT ID: NCT01011257 Withdrawn - Clinical trials for Coronary Artery Disease

Studying the Efficacy of Aspirin & Clopidogrel in Healthy Subjects With Stable Coronary Artery Disease.

Dual-Dosing
Start date: September 2009
Phase: Phase 4
Study type: Interventional

The investigators will test the hypothesis that aspirin or clopidogrel taken twice daily will augment their antiplatelet efficacy in patients with an elevated platelet turnover (as measured by the proportion of reticulated (young) platelets) compared with once daily dosing.

NCT ID: NCT01009996 Withdrawn - Clinical trials for Coronary Artery Disease

Efficacy Study of Kissing Drugā€Eluting Balloons in Coronary Bifurcation Lesions

KISSING DEBBIE
Start date: October 2009
Phase:
Study type: Observational

KISSING DEBBIE's aim at assessing angiographic and clinical outcomes of provisional treatment of coronary bifurca6on lesions according to TAP sten6ng with BMS and final kissing DEB

NCT ID: NCT01003795 Withdrawn - Clinical trials for Coronary Artery Disease

Promus - Registry Experience at the Washington Hospital Center, Drug-eluting Stent (DES)

P-REWARDS
Start date: October 2009
Phase:
Study type: Observational

Single-center registry of patients treated with at least one Promus, everolimus-eluting, Stent, with the primary objective to assess clinical success and safety at 30 days, 6 months and 1 year post-implantation.

NCT ID: NCT01002495 Withdrawn - Myocardial Ischemia Clinical Trials

Gene Therapy for the Treatment of Chronic Stable Angina

Start date: March 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of catheter based injections of VM202 into the heart.

NCT ID: NCT00853541 Withdrawn - Heart Failure Clinical Trials

Calcium, Phosphate, Renal Impairment and Coronary Artery Disease in the Cardio-renal Syndrome, The CAPRICORN-CRS Study

CAPRICORN
Start date: March 2009
Phase: N/A
Study type: Observational

Heart failure (HF) is a major public health problem, which affects about 5 million Americans.HF is when the heart muscle does not pump as much blood as the body needs. As a result of this,the body has difficulties in keeping an optimal fluid status. The fluid status of the body is regulated by both the heart and the kidneys. Due to the strong interaction between the heart and the kidneys, heart failure can result in a slight decreased kidney function as well. It is known that people who primarily suffer from chronic kidney disease (CKD) have a higher risk of developing arterial calcifications. Calcification of the arteries is caused by deposits of calcium within the walls of the blood vessels. Calcifications of the arteries may result in a loss of elasticity of the blood vessels. Recent research studies have shown that people with CKD have stiffer blood vessels which in these people, is associated with a higher chance of developing cardiovascular diseases. However, it is not known whether a decrease in kidney function in people with HF results in arterial calcification as well. In addition, it is not known whether this is also associated with a higher risk of developing cardiovascular diseases (diseases of the heart and blood vessels.) We are asking you to take part in this study because you have HF combined with some decrease in your kidney function. The purpose of this study is to see whether people with HF and a decrease in kidney function do have a higher chance of developing arterial calcifications. We will do this by comparing the results of the following; 1) several blood tests, 2) pictures taken of your heart by echocardiogram and computed tomography (CT) scan, and 3) measurements of the elasticity of your arteries. All of these tests are routinely used in clinical care. However, there have not been any research studies that have compared these results to see how they relate to arterial calcification in people with HF who have a decrease in kidney function. We also want to see whether people with HF and a decreased kidney function are at a higher risk of developing cardiovascular diseases. This study is being performed at Massachusetts General Hospital (MGH), in Boston Massachusetts. We expect to enroll a total of 150 subjects at MGH.

NCT ID: NCT00817830 Withdrawn - Clinical trials for Erectile Dysfunction

Cardiovascular Safety Study of Lodenafil Carbonate in Patients With Coronaropathy During Physical Effort

Start date: November 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the safety of lodenafil carbonate in patients with coronaropathy, evaluating the response of the body facing physical effort, including both heart and respiratory components, with and without use of lodenafil carbonate 80mg.