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Cancer clinical trials

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NCT ID: NCT04978805 Completed - Cancer Clinical Trials

Progressive Relaxation Exercise on Dyspnea, Pain and Sleep Quality

Progressive
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

This study was planned to examine the effect of progressive relaxation exercises applied to lung cancer patients receiving chemotherapy on dyspnea, pain and sleep quality.

NCT ID: NCT04972409 Recruiting - Cancer Clinical Trials

Value of Information of Secondary dAta in ONCOGEnetics

VISAGE-ONCO
Start date: December 9, 2019
Phase:
Study type: Observational

VISAGE-ONCO study is a qualitative transversal study aiming to identify and describe processes and mechanisms that explain in cancerology the feelings and experience of patients and health professionals with regard to the possibility of having access to secondary findings generated by the use High-speed exome sequencing . Semi-structured interviews will be conducted with patients and health professionals to answer this aims from 2 situations. The first situation is in the context of the standard practice for theranostic purposes, where somatic and constitutional analysis of the various genes involved in carcinogenesis is carried out systematically in parallel. Patients are informed that the analysis of these genes may reveal the existence of a genetic predisposition to another type of cancer than the one for which patients have consulted, with a risk for themselves or their relatives, which could modify their management. This targeted information on genetic predisposition genes to cancer is therefore provided as part of standard management for theranostic purposes, but without any detailed exploration of the reasons why patients wanted to be informed. The second situation is in the framework exome analysis position in the strategy of genetic redisposition factors identification in early-onset cancer study (EX²TRICAN NCT04141462) where all the genes identified in human pathology are part of the analysis. Patients have the possibility of accessing a result concerning a gene that may or may not be linked to a hereditary cancer risk if patients have ticked off in the consent form the wish to be informed. Therefore, two distinct questions arise: - That of understanding the wish of patients to be given back actionable data which can be identified in a fortuitous way within the framework of standard management for theranostic purposes and in EX²TRICAN, by taking into account the fact that these data can constitute an opportunity for the patient in terms of management; but patients also constitute a risk of transmission for they relatives, and a psychological risk by the anxiety generated; - The wish to have access - or not - to data which are not actively sought today within the framework of standard care for theranostic purposes and in EX²TRICAN (genetic alterations increasing the risk of cardiovascular or metabolic diseases), but which could be proposed in a systematic way in the future because of their actionable character.

NCT ID: NCT04972201 Recruiting - Cancer Clinical Trials

A Proof of Concept Study of Pan-cancer Early Detection by Liquid Biopsy

PROMISE
Start date: July 5, 2021
Phase:
Study type: Observational

PROMISE is a multi-center, prospective and proof of concept study aimed to evaluate the performance of 3 prototype assays of cell-free DNA (cfDNA) mutation, cfDNA methylation and microRNA (miRNA) expression in early detection of multi-cancer. Assay(s) will be selected for further development. The study will enroll approximately 2035 participants, including participants with cancers and healthy participants.

NCT ID: NCT04967209 Recruiting - Breast Cancer Clinical Trials

Investigation of a Digital Healthy Habits Program for Individuals With Breast Cancer

Start date: July 5, 2021
Phase:
Study type: Observational

This mixed methods study will involve obtaining user feedback on the first 4 weeks of the Healthy Habits for Cancer (HCC) Program. Short pre and post surveys and in-depth qualitative interviews will be conducted exploring their views on the app (features they liked and didn't like), the extent to which they believe the app would have to be further adapted, how they would feel about such an app being embedded in their cancer care and when in their care pathway they would like to be offered it.

NCT ID: NCT04966520 Recruiting - Cancer Clinical Trials

Accelerated Neuromodulation to Alleviate Cognitive Deficits Due to Cancer Therapy

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This project is aimed at the discovery of neuro-modulation techniques that may alleviate chemotherapy induced cognitive deficits (CICD), especially in executive (higher-order) cognitive function (EF).

NCT ID: NCT04964960 Not yet recruiting - Cancer Clinical Trials

Pembro+Chemo in Brain Mets

Start date: July 2021
Phase: Phase 2
Study type: Interventional

The goal of this study is to evaluate whether providing Pembrolizumab prolongs survival and preserves quality of life while minimizing side effects for patients with NSCLC with untreated asymptomatic brain metastasis.

NCT ID: NCT04962529 Recruiting - Breast Cancer Clinical Trials

Breast Cancer Liquid Biopsy Trial

Start date: September 28, 2020
Phase:
Study type: Observational

The purpose of this study is to test an ideated product concept with an intended use as a blood-based testing alternative for patients with symptoms of recurrent metastatic breast cancer when surgical tissue biopsy is infeasible or invasive biopsy is medically contraindicated. The intended use is to aid in the diagnosis of suspected breast cancer recurrence & provide standard of care Hormone Receptor (HR)/HER2 status, which inform immediate treatment decisions.

NCT ID: NCT04961827 Not yet recruiting - Cancer Clinical Trials

Eat Well After Cancer: a Randomized Controlled Trial of a Self-efficacy Based Dietary Intervention Among Chinese Cancer Survivors

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

To develop and test the effectiveness of a dietary intervention aiming to enhance self-efficacy through sending images through instant messaging.

NCT ID: NCT04961203 Recruiting - Cancer Clinical Trials

Pathways of Patients Followed in Palliative Care at the University Hospital of Strasbourg: a Retrospective Pilot Study

Palliatif
Start date: June 15, 2021
Phase:
Study type: Observational

In view to develop a study design for a study that would analyze the pathways of palliative care prospectively, this work will identify the individual factors that would be significantly associated with typical pathways of palliative care.

NCT ID: NCT04960332 Not yet recruiting - Cancer Clinical Trials

Effect of Negative Pressure Wound Therapy After Surgical Removal of Deep-Seated High-Malignant Soft Tissue Sarcomas of the Extremities and Trunk Wall.

Start date: July 2021
Phase: N/A
Study type: Interventional

The purpose of this research project is to improve the surgical treatment of Soft Tissue Sarcoma (STS) treatment based upon a Randomized Controlled Trial (RCT). We want to evaluate the effect of the use of Negative Pressure Wound Therapy (NPWT) versus a conventional wound dressing on postoperative wound complications after surgical removal of deep-seated high-malignant STS of the extremities or trunk wall.