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Cancer clinical trials

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NCT ID: NCT06089967 Enrolling by invitation - Cancer Clinical Trials

Immune-Related Adverse Events and Associated Biomarkers in Patients Receiving Cancer Immunotherapy

IMBARC
Start date: October 5, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this project is to collect body samples like blood and tissue and health information from people receiving immune-based treatment for cancer. The body samples and health information will be stored for future research to understand more about side effects related to immune-based treatments for cancer.

NCT ID: NCT06089954 Enrolling by invitation - Cancer Clinical Trials

Penn Medicine Biobank Return of Results Program

ROR
Start date: October 20, 2023
Phase: N/A
Study type: Interventional

The goal of this hybrid type 1 effectiveness-implementation study is to evaluate and compare different ways of delivering genetic research results to participants. The main questions the study aims to answer are: - Is sharing actionable genetic research results with participants through a multimedia patient-informed eHealth intervention (e.g. patient portal) no worse than sharing results by telephone or videoconference with a genetic counselor? - Will research participants access an eHealth educational intervention or chatbot education to learn about research results being offered and the option to decline learning their individual research results and how frequently participants choose to decline actionable research results? - Who benefits less and more from digital intervention with return of actionable research results and what barriers exist to using these tools for return of research results outside this study? Participants in the biobank will be offered digital tools to learn about research results being offered and the option to decline receiving these results. Those who don't decline and have an actionable result will be randomly assigned to receive their results with a genetic counselor or through an eHealth portal. Participants will complete surveys before and after receipt of results to understand patient experiences with these methods of education and return of results to determine if digital tools can be used to help ensure more patients get access to research results which could impact their health.

NCT ID: NCT06039488 Enrolling by invitation - Cancer Clinical Trials

Effectiveness of a Cancer Exercise Program

Start date: August 15, 2021
Phase: N/A
Study type: Interventional

The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (>18 years old) with cancer.

NCT ID: NCT05979987 Enrolling by invitation - Cancer Clinical Trials

UCLA Health Patient Health Maintenance Text Reminder July 2023

Start date: July 27, 2023
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text message reminders impact patient engagement with primary care. This prospective randomized control trial is being implemented in conjunction with UCLA Health's larger quality improvement initiative (the My Action Plan Quality Improvement Initiative) in order to improve primary care preventive measure completion rates.

NCT ID: NCT05913999 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Serial PET MPI in Patients Undergoing Cancer Treatment

Start date: June 1, 2023
Phase:
Study type: Observational

This study aims to evaluate the effects of cardiotoxic cancer therapies on myocardial blood flow (MBF) and perfusion in a prospective sample of VA patients.

NCT ID: NCT05885880 Enrolling by invitation - Cancer Clinical Trials

Blue-Button Regional Trial Screening

Start date: October 15, 2023
Phase: N/A
Study type: Interventional

Enrollment in clinical trials predicts better survival in the most common cancer types including breast cancer, and testing and proving the efficacy of new treatments relies on successfully conducting clinical trials. However, approximately one fifth of cancer clinical trials fail due to insufficient patient enrollment, and only about 6% of adult cancer patients are enrolled onto clinical trials. Barriers remain for patient participation in clinical trials, especially for cancer patients. One specific barrier is trial identification and awareness of trial availability for both patients and providers. This trial tests the hypothesis that by integrating clinical trial eligibility screening into part of routine care in a way that requires little effort and by making that screening site agnostic, the Blue-Button matching functionality will increase overall cancer clinical trial enrollment, and may also result in more diverse clinical trial participants that better reflect the U.S. cancer population. Moreover, regardless of changes in enrollment, the Blue-button screening may allow screening to be done more quickly with fewer human resources when compared to current methods. Identification of potential trial opportunities, however, is only the first barrier to trial enrollment, so this study includes additional examination of barriers subsequent to the identification of relevant trials by cataloging patient-level barriers that prevent enrollment of patients in identified trials.

NCT ID: NCT05879211 Enrolling by invitation - Cancer Clinical Trials

Goal Concordant Care Learning Laboratory

Start date: July 12, 2023
Phase: N/A
Study type: Interventional

The goal-concordant care lab will develop and test strategies to optimize communication in advanced serious illness.

NCT ID: NCT05870176 Enrolling by invitation - Cancer Clinical Trials

ActivityChoice: Implementing Clinic-Based Physical Activity Program Choices for Cancer Survivors

Start date: September 11, 2023
Phase: N/A
Study type: Interventional

Cardiovascular disease, the number one leading cause of death in the United States, is highly prevalent in cancer survivors. Physical activity can reduce risk, and referrals to programs addressing survivors' choices are highly recommended from providers in cancer survivorship, though rarely implemented. The study team proposes to develop ActivityChoice, a clinic-based implementation program, using patient narrative decision aids to support choices to a group in-person, group virtual, or self-monitored digital health physical activity program.

NCT ID: NCT05793788 Enrolling by invitation - Cancer Clinical Trials

UCLA Health Patient Health Maintenance Outreach Text Message

Start date: March 9, 2023
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text messages impact patient engagement with primary care. This prospective randomized control trial is being implemented in conjunction with UCLA Health's larger quality improvement initiative (the My Action Plan Quality Improvement Initiative) in order to improve primary care preventive measure completion rates.

NCT ID: NCT05791942 Enrolling by invitation - Cancer Clinical Trials

UCLA Health Patient Health Maintenance Text Reminder

Start date: March 23, 2023
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text message reminders impact patient engagement with primary care. This prospective randomized control trial is being implemented in conjunction with UCLA Health's larger quality improvement initiative (the My Action Plan Quality Improvement Initiative) in order to improve primary care preventive measure completion rates.