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Cancer clinical trials

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NCT ID: NCT06446115 Not yet recruiting - Cancer Clinical Trials

Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer

Start date: November 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if the use of virtual reality during chemotherapy treatment helps participants achieve an improvement in distress, which may include unpleasant experience, anxiety, depression and/or pain. Participants will: - Be randomly assigned to one of two available groups (virtual reality or standard of care) - Participations will only be during one chemotherapy session. - Those assigned to virtual reality: - The research team will provide a virtual reality - The research team will provide guidance on how the headset works and will be available to assist with any questions or concerns. - Participants will also be able to choose different relaxing backgrounds depending on their preference. headset during the chemotherapy session for 15 to 30 minutes - Those assigned to the standard of care: - The research team will provide the participants with the opportunity to choose a preferred activity such as reading a book, watching television, etc.

NCT ID: NCT06445140 Not yet recruiting - Cancer Clinical Trials

Dynamics of Motivational Factors for Physical Activity and Nutrition in Oncogeriatrics

MONAGE
Start date: May 28, 2024
Phase: N/A
Study type: Interventional

Oncogeriatric: a collaboration between oncologists and geriatricians which aims to ensure that all elderly cancer patients receive treatment adapted to their condition, thanks to a multidisciplinary and multi-professional approach. This project aims to gain a better understanding of the motivational determinants of PA and nutrition in elderly cancer patients. It has a dual objective: 1. to identify clusters/groups in patients on the basis of daily motivational factors focusing on PA and nutrition 2. on the basis of the results obtained in (1), to propose an interventional study based on the previously established clusters, in order to examine the effects of a behavioral intervention on patients' adherence to PA and nutrition, both agreed according to an individualized goal and defined in agreement with the patient and the multidisciplinary team, taking into account the recommendations.

NCT ID: NCT06444477 Not yet recruiting - Cancer Clinical Trials

Molecular Analysis of Thrombocytopenia and Cancer (MATAC): Investigating Antigenic Mimicry Between Platelets and Tumor Cells in Patients With Immune Thrombocytopenia (ITP) Associated With Cancer

MATAC
Start date: June 2024
Phase:
Study type: Observational

The association between hematologic malignancies and ITP is well described, but this link is much less clear with solid cancers. In cases of ITP associated with cancers, specific cancer treatment can lead to remission or even cure of ITP. Thus, our hypothesis was that chronic expression of GPIIB by tumor cells could have initiated an autoimmune loop against GPIIB, leading to the onset and perpetuation of ITP.

NCT ID: NCT06441773 Not yet recruiting - Cancer Clinical Trials

Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase

REHABIM
Start date: November 1, 2024
Phase: N/A
Study type: Interventional

Lung cancer is highly prevalent, with approximately 46,363 new cases in 2018, accounting for 20.6% of cancer deaths in France. At diagnosis, 70% of patients have advanced or metastatic cancer, treatable only by palliative care. Respiratory rehabilitation aims to reduce symptoms, enhance performance, increase autonomy, and improve patients' quality of life. While effective for COPD patients and other conditions causing dyspnea, its benefits in advanced, non-operable lung cancer are less studied. Some studies have shown the feasibility and safety of respiratory rehabilitation, but few have compared its impact on non-operable lung cancer patients or assessed its effect on quality of life. The main objective of the proposed study is to evaluate the impact of a respiratory rehabilitation program on the quality of life of patients with non-small cell lung cancer (NSCLC) undergoing maintenance chemotherapy and immunotherapy, compared to a control group receiving standard care.

NCT ID: NCT06441513 Recruiting - Cancer Clinical Trials

The Preventive Effect of Chemotherapy-induced Hand-foot Syndrome

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

this study will use traditional Chinese medicine bath with no obvious side effects combined with case tracking management mode to form nursing measures to prevent hand foot syndrome. A randomized controlled trial design will be used to collect cases of hand foot syndrome (HFS) that did not appear after chemotherapy in the ward of the Department of chemotherapy, Peking University Third Hospital, and carry out nursing intervention.

NCT ID: NCT06440005 Recruiting - Cancer Clinical Trials

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Start date: May 2024
Phase: Phase 1
Study type: Interventional

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously. Dosing of AGX101 will be repeated once every 3 weeks. Participants may continue study treatment until disease progression, unacceptable toxicity, or consent withdrawal. Subjects will attend an end of treatment visit and will receive two safety follow-up telephone contacts up to 90 days following the last dose of study drug.

NCT ID: NCT06439316 Completed - Cancer Clinical Trials

Physical Function and Mental Health in Cancer Survivors

Start date: January 1, 2007
Phase:
Study type: Observational

The goal of this observational study is to evaluate the joint prognostic effects of physical function and mental health on survival of cancer survivors.

NCT ID: NCT06436651 Recruiting - Cancer Clinical Trials

Digital Storytelling in Symptom Management Pediatric Oncology

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

The aim of this clinical study is to evaluate the effectiveness of the digital storytelling method in symptom management in children diagnosed with oncology. It will also provide information about children's experiences with Digital Storytelling and the use of the method. The main questions it aims to answer are: - Is there a difference between the anxiety scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the fatigue scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the nausea scores of children who applied the Digital Storytelling Method and those who did not? - Is there a difference between the pain scores of children who applied and did not apply the Digital Storytelling Method? Participants: Complete the first stage data forms. Visit the clinic every 7-15 days for the digital storytelling process, which consists of 4 stages. After the storytelling process is completed, have a process evaluation meeting with the researcher.

NCT ID: NCT06435117 Not yet recruiting - Cancer Clinical Trials

Cancer Prevention Among Individuals With Mental Ill-health: Patient Navigation for Primary Cancer Prevention

CO-CAPTAIN
Start date: June 2024
Phase: N/A
Study type: Interventional

Prevention is essential for reducing cancer-related mortality. However, people with mental ill-health often face difficulties in accessing cancer prevention services. The EU-funded CO-CAPTAIN project aims to co-adapt and implement the Patient Navigation Model for primary cancer prevention in this underserved population. This evidence-based and patient-centred intervention aims to support patient empowerment through removal of systemic barriers, provide social support and promote timely access to primary prevention services.

NCT ID: NCT06434402 Recruiting - Cancer Clinical Trials

A Virtual, Group-Based, Expressive Writing Intervention for Survivors of Adolescent and Young Adult Cancer

Start date: May 22, 2024
Phase: N/A
Study type: Interventional

To learn more about the experiences of adolescent and young adult cancer survivors and investigate whether a group-based writing intervention can help to improve quality of life of adolescent and young adult cancer survivors.