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Cancer clinical trials

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NCT ID: NCT05441163 Not yet recruiting - CANCER Clinical Trials

ProActIF-01 Trial: Randomized Phase II Study of Evaluation of an Individualized Program of Nutrition and Adapted Physical Activity in Frail Patients With Advanced Lung or Digestive Cancers

Start date: October 15, 2022
Phase: N/A
Study type: Interventional

The ProActIF-01 trial aims to assess the efficacy of a supervised 8-week combined APA and nutrition individualized program on survival without HRQoL deterioration (European Organization for Research and Treatment of Cancer-Quality of Life-C30 questionnaire, EORTC QLQ-C30, 1 targeted dimension), in advanced lung or digestive cancer patients.

NCT ID: NCT05435365 Not yet recruiting - Cancer Clinical Trials

Investigating The Experiences of Patients In Immunotherapy Clinical Trials

Start date: August 22, 2022
Study type: Observational

It has been observed before that participation in medical trials has been in favor of specific demographic groups. But research pointing out which trial attributes impact participation positively or negatively is sparse. This study invites various participants to collect more data on their immunotherapy clinical experiences. The goal is to know which factors always limit how patients participate or complete the medical study they are first interested in. The data obtained in the trial will be assessed through a variety of demographic lenses to discover patterns that might improve the experience of immunotherapy patients in the future.

NCT ID: NCT05435066 Not yet recruiting - Cancer Clinical Trials

Development and Validation of Harbinger Health Test for Early Cancer Detection

Start date: June 20, 2022
Study type: Observational

This is a prospective, multi-center, observational study with a collection of biospecimens and clinical data from approximately 10,000 participants from up to 40 clinical network sites and locations in the United States. The objective of this study is to collect blood samples, tissue samples, and associated clinical data from participants with a variety of solid tumor and hematologic cancers and non-cancer participants for testing and the development of a screening test for early cancer detection.

NCT ID: NCT05434871 Not yet recruiting - Cancer Clinical Trials

Yoga in Pediatric Cancer

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

Pediatric cancer patients and their families experience biopsychosocial difficulties as a result of the long and difficult treatment procedure, which have a severe impact on their quality of life. These difficulties might arise as a result of cancer and its treatment. Fatigue, pain, and an impaired motor skills are all common issues. These issues result in body structure and function deficits, as defined by the International Classification of Functioning-Child and Youth (ICF-CY), and have a negative impact on children's activity and participation levels. Yoga is a form of exercise that incorporates breathing methods, physical postures, and meditation. Yoga appears to relieve fatigue and improve quality of life in pediatric cancer patients, according to preliminary studies. However, no randomized controlled trial has been conducted in this population to determine the effectiveness of yoga. The purpose of this study is to assess children's quality of life, fatigue, pain, motor proficiency, participation, coping, and motivation; also to look at the effects of parents on quality of life, depression, fatigue, and care burden in a randomized controlled study.

NCT ID: NCT05434208 Not yet recruiting - Cancer Clinical Trials

Effects of Nurse-led Telephone Based Service for Early Palliative Care (PALTEL)

Start date: September 2022
Phase: N/A
Study type: Interventional

Non-pharmacological, interventional, two-arm, randomized controlled trial. Early Palliative Care cancer patients will be randomized to active telephonic follow-up program by specialist nurses until end-of-treatment (28 days) (group A, research arm) or face-to-face visit at end of treatment (28 days) (group B, control arm). There are few studies demonstrating the efficacy of nurse-led telephone service in advanced cancer patients but it's still quite unclear how they can affect quality of life, symptom burden and caregivers distress. In addition, the ideal structure, method and timing of telephone follow-up as well are often not considered and have not been articulated. Nurse-led management by phone to advanced cancer patients could, for some patients, dramatically improve their care experience, quality of life and symptoms control. Investigators want to build an effective and sustainable approach for implementing the telephone service providing nurse-led telephone-based support to Early Palliative Care cancer patients. The aim is to investigate the feasibility of a proactive approach and measure the efficacy in terms of symptom management, satisfaction with care and impact on health care resources.

NCT ID: NCT05433974 Not yet recruiting - Cancer Clinical Trials

Pre-therapeutic Analysis of the Individual Radiosensitivity of Cancer Patients in Luxembourg (APRI-Lux): Prospective National Interventional Study With Minimal Risk

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Pre-therapeutic analysis of the individual radiosensitivity of cancer patients in Luxembourg

NCT ID: NCT05433636 Not yet recruiting - Pain Clinical Trials

Mindful Waiting Room

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This will be a single-site, five-arm, parallel group randomized control trial involving patients seeking integrative healthcare. We will compare four different styles of 5-minute, audio-recoded mindfulness practices delivered in the clinic waiting room to a 5-minute audio-recording about integrative healthcare. A secondary sub-analysis will investigate the most effective mindfulness practice style for patients presenting at the clinic with elevated anxiety, depression, or pain.

NCT ID: NCT05431439 Not yet recruiting - Cancer Clinical Trials

Omics of Cancer: OncoGenomics

Start date: July 6, 2022
Study type: Observational

Background: Cancer is a leading cause of death in the United States. Researchers want to know more about how cancer develops and grows. They want to understand more about cancers that run in families. This information will help them find better ways to diagnose and treat cancer. Researchers need to collect data from many people who either have cancer or who may get cancer. Objective: To establish a registry of data about people with cancer. The registry will be linked to a database with information about their genetics. Eligibility: People aged 4 weeks and older with a diagnosis of any cancer. People with precancerous conditions or with a family history of an inherited cancer are also needed. Design: Participants will answer questions about their medical history. This visit can be in-person or by phone. Participants will provide blood and saliva samples. Researchers will also collect any samples the participants may already have given in the past. These may include tumor biopsies or samples of bone marrow or other body fluids. No blood will be collected from children younger than 3 years. No new surgeries or biopsies will be done for this study. The samples will be used for genetic research. Researchers will follow up with participants once a year. They will get an updated medical history. They will ask for any new biopsies or other tissue samples. They may collect new saliva and blood samples. Participants may continue in the study for the rest of their lives.

NCT ID: NCT05427240 Not yet recruiting - Cancer Clinical Trials

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Start date: July 2022
Phase: N/A
Study type: Interventional

This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optimal ways to deliver clinical genetic testing in eligible individuals, while maintaining quality of care and favorable cognitive, affective and behavioral outcomes.

NCT ID: NCT05417438 Not yet recruiting - Cancer Clinical Trials

Survivor mHealth: Wearable Devices in Cancer Survivors

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

The Survivor mobile health (mHealth) study is testing the use of wearable devices (Fitbits) and a smartphone application in cancer survivors. The goal of the program is to increase survivor's physical activity levels. The Fitbit will be synced to the app and participants will receive messages and notifications about their activity levels. Participants will also complete surveys through the app asking how useful it is and ways to improve it. The study team will conduct qualitative interviews at the completion of the 3 months to see how participants liked the program, and ways it can be improved and make it more specific to cancer survivors. The study team will also conduct interviews with providers and clinic staff to assess their perceptions of patient digital health programs and preferences for receiving patient-generated health data.