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Atrial Fibrillation clinical trials

View clinical trials related to Atrial Fibrillation.

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NCT ID: NCT03963349 Not yet recruiting - Clinical trials for Paroxysmal Atrial Fibrillation

THERMOCOOL SMARTTOUCH®SF Catheters With Ablation Index Study

STSF
Start date: May 28, 2019
Phase:
Study type: Observational [Patient Registry]

Prospective, single-center, real word study of consecutive subjects who undergo radiofrequency ablation for paroxysmal AF using THERMOCOOL SMARTTOUCH®SF (STSF) Catheter guiding by Ablation Index (AI).

NCT ID: NCT03962166 Not yet recruiting - Atrial Fibrillation Clinical Trials

Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE

Start date: May 2019
Phase:
Study type: Observational

Post-operative atrial fibrillation (POAF) is frequently observed after open-heart surgery. Despite numerous attempts to predict POAF, it remains a challenge to correctly identify the patients at risk. New technologies are available but not yet in cooperated in clinical guidelines and prediction models. We aim at identifying patients at risk of AF occurrence/recurrence after open-heart surgery by use of signal processed surface ECG (wavECG). The study is an explorative, prospective cohort study of 100 patients undergoing first-time elective open-heart surgery in the Left Atrial Appendage Closure by Surgery-2 (LAACS-2) trial (NCT03724318). Patients are examined by electrocardiogram (ECG), wavECG, transthoracic echocardiography and continuous heart rhythm monitoring. Primary endpoint is occurrence/recurrence of AF. Left ventricular diastolic dysfunction as evaluated by wavECG will be used to predict incidence of primary endpoint.

NCT ID: NCT03961490 Recruiting - Atrial Fibrillation Clinical Trials

Contribution of Image Fusion in Percutaneous Left Atrial Occlusion procédures (Fusion Image)

Start date: June 9, 2017
Phase:
Study type: Observational

Atrial fibrillation is the most common rhythm disorder, affecting 2 to 3 percent of the population. One of the major complications is the occurrence of thromboembolic events, the thromboembolic risk can be predicted by the ChadsVasc score. Anticoagulant treatment is therefore almost always indicated, however, in view of the target population, anticoagulant treatment is sometimes contraindicated, justifying the appearance of alternative treatment such as occlusion of the left auricle by surgical or percutaneous means, with the placement of a prosthesis in the left auricle. Image fusion is a new imaging technique aimed at improving the spatial view of 2D images (made during a catheterization session) by repositioning in real time a 3D model obtained by reconstruction from scanner images of the structure of interest. Once the model has been redesigned, it follows all the consequences that the hemodynamicist wants to take and thus guides the gesture as well as possible. The purpose of this project is to evaluate the contribution of image fusion to per cutaneous occlusion procedures of the left atrium. This contribution will be evaluated by comparing the procedure time, the irradiation time, the amount of contrast material used between the procedures performed with the image fusion technique and without this new technique.

NCT ID: NCT03960346 Completed - Atrial Fibrillation Clinical Trials

Cryoballoon and Associated Esophageal Effects

Start date: November 25, 2015
Phase: N/A
Study type: Interventional

The primary objectives are to determine the correlation between rate of temperature decline and nadir cryoballoon temperatures rate of temperature decline and nadir esophageal temperatures during pulmonary vein isolation. To accurately measure the distance between the esophagus and the ostium of each pulmonary vein intra-operatively. To attempt to create recommendations for esophageal temperature-guided ablation in order to increase the safety profile of cryoballoon pulmonary vein isolation (PVI) by providing one center's experience. By trending cryoballoon ablation temperatures and subsequent esophageal temperatures, data trends may emerge and be predictive for esophageal ulceration formation. These trends may include: - Distance between esophagus and pulmonary vein in patients who developed post-ablation esophageal ulcerations - Intra-procedure esophageal temperatures in patients who developed post-ablation esophageal ulcerations - Intra-procedure cryoballoon temperatures in patients who developed post-ablation esophageal ulcerations As well as to associate the development of symptoms (including dysphagia, chest pain, fever, "heartburn," or odynophagia) with the presence of ulcerations.

NCT ID: NCT03957187 Not yet recruiting - Atrial Fibrillation Clinical Trials

Prevalence and Clinical Associates of Iron Deficiency in Patients With Atrial Fibrillation

AID-AF
Start date: May 2019
Phase:
Study type: Observational

To estimate the prevalence of iron deficiency (ID) in patients with atrial fibrillation

NCT ID: NCT03950843 Recruiting - Atrial Fibrillation Clinical Trials

A Clinical Trial to Evaluate the Efficacy and Safety of CKD-825 in Patients With Atrial Fibrillation

Start date: April 23, 2019
Phase: Phase 3
Study type: Interventional

to Evaluate the Efficacy and Safety of CKD-825 in Patients With Atrial Fibrillation

NCT ID: NCT03950076 Not yet recruiting - Atrial Fibrillation Clinical Trials

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)

ENRICH-AF
Start date: September 2019
Phase: Phase 4
Study type: Interventional

To assess whether edoxaban (60/30 mg daily) compared to standard of care (either no antithrombotic therapy or antiplatelet monotherapy) reduces the risk of stroke (composite of ischemic, hemorrhagic and unspecified stroke) in high-risk atrial fibrillation (CHA2DS2-VASc ≥2) patients with previous intracranial hemorrhage.

NCT ID: NCT03943927 Not yet recruiting - Clinical trials for Post-operative Atrial Fibrillation

Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery

PREEMPTIVE
Start date: December 2019
Phase: N/A
Study type: Interventional

Metoprolol is frequently administered to cardiac surgery patients to reduce the incidence of postoperative atrial fibrillation (PoAF). Metoprolol is metabolized by the enzyme CYP2D6, which is known to have many mutations that could influence a patient's ability to metabolize the drug. In this prospective clinical trial, the investigators will determine the genotype of CYP2D6 for patients undergoing cardiac surgery, provide an altered dosing recommendation for metoprolol, then report the relative effectiveness in managing PoAF for each pharmacogenetic- guided dosing category. The investigators will also explore the effects of personalized metoprolol dosing recommendations on outcomes in hospital length of stay, cost, and provider participation.

NCT ID: NCT03943693 Recruiting - Atrial Fibrillation Clinical Trials

Dual Versus Single Shock for Cardioversion of Atrial Fibrillation

Start date: April 1, 2019
Phase: Phase 4
Study type: Interventional

We aim to investigate the immediate success rate (rate of termination of atrial fibrillation) of dual shock cardioversion compared with standard single shock cardioversion in patients with baseline characteristics adversely influencing successful cardioversion. Baseline characteristics known to reduce the success rate of single shock cardioversion include: increased BMI, chronic obstructive pulmonary disease, sleep apnea, enlarged left atrium, longer duration of atrial fibrillation and use of amiodarone.

NCT ID: NCT03940066 Not yet recruiting - Atrial Fibrillation Clinical Trials

Evaluation of Ambulatory Monitoring of Patients After High-risk Acute Coronary Syndrome Using Two Different Systems: Biomonitor-2 and Kardia Mobile

Monitor- ACS
Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the efficacy of monitoring after discharge of patients with high-risk acute coronary syndrome.