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Atrial Fibrillation clinical trials

View clinical trials related to Atrial Fibrillation.

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NCT ID: NCT03774550 Not yet recruiting - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Ablation: Radiofrequency or Cryoablation?

ARCFA
Start date: December 20, 2018
Phase:
Study type: Observational

The study aims to compare 3 techniques routinely used for paroxysmal atrial fibrillation ablation: radiofrequency catheter ablation without contact-force, radiofrequency catheter ablation with contact-force and cryoablation. The hypothesis is the non-inferiority between the 3 techniques in terms of free-from atrial fibrillation survival (primary criteria). It will also compare lenght of procedure, radioscopy time and immediate complications (secondary criteria).

NCT ID: NCT03772457 Not yet recruiting - Clinical trials for Intracranial Hemorrhages

Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban

Start date: January 1, 2019
Phase:
Study type: Observational

This study was aimed at patients with newly diagnosed stroke / TIA associated with nonvalvular atrial fibrillation. We will observe the effect of early using rivaroxaban anticoagulation on hemorrhagic transformation, and explore the predictive value of multi-mode MRI infarct volume / MMP-9 on hemorrhagic transformation after anticoagulation therapy.

NCT ID: NCT03769207 Enrolling by invitation - Atrial Fibrillation Clinical Trials

Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias

Start date: December 6, 2018
Phase: N/A
Study type: Interventional

This post-marketing study is conducted to characterize the ability of Apple Watch rhythm analysis software to identify Atrial Fibrillation (AF) and facilitate subsequent clinical evaluation among users who contact AppleCare.

NCT ID: NCT03765242 Active, not recruiting - Atrial Fibrillation Clinical Trials

Evaluation of Safety and Effectiveness on Oral Anticoagulants

RCR-OAC
Start date: September 21, 2018
Phase:
Study type: Observational

This study is to compare the risk of major bleeding among oral anticoagulant (OAC)-naïve non-valvular atrial fibrillation (NVAF) patients initiating treatment

NCT ID: NCT03763500 Recruiting - Atrial Fibrillation Clinical Trials

Evaluation of the Added Value of an Internet-based Educational Program for Patients With Atrial Fibrillation.

AMADEUS
Start date: December 3, 2018
Phase: N/A
Study type: Interventional

This study is prospective, open and randomized concerning the value of an Internet-based educational program for patients with atrial fibrillation compared to "care as usual".

NCT ID: NCT03761394 Not yet recruiting - Stroke Clinical Trials

Pulsewatch: Smartwatch Monitoring for Atrial Fibrillation After Stroke

Start date: December 2018
Phase: N/A
Study type: Interventional

The goal of this research study is to develop a smartphone application capable of monitoring paroxysmal atrial fibrillation (pAF) in people who have survived a stroke or transient ischemic attack (TIA) and are age 50 and older. The study team plans to develop a highly effective and easy to use cardiovascular surveillance system to monitor patients for pAF on a nearly continuous basis. People involved in the development of this system include patients, their caregivers, health care providers, and computer programmers.

NCT ID: NCT03760874 Recruiting - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Research Database

Start date: June 13, 2013
Phase:
Study type: Observational [Patient Registry]

All patients with atrial fibrillation who are treated with vitamin-k antagonists (warfarin, phenprocoumon) or non vitamin K oral anticoagulants (Dabigatran, Rivaroxaban, Apixaban, Edoxaban) in real world settings will be recorded in this register. Within this register a characterization of patients and therapy (with regard to medication, dose and duration) will be done. On basis of defined clinical relevant end points the long-term efficacy and safety will be evaluated.

NCT ID: NCT03760705 Active, not recruiting - Clinical trials for Coronary Artery Disease

Singapore Cardiac Longitudinal Outcomes Database

SingCLOUD
Start date: July 5, 2013
Phase:
Study type: Observational [Patient Registry]

The research project aims to perform data extraction, integration and analysis across multiple clinical, administrative, financial and pharmacy databases in the participating institutions. The key data components will include clinical cardiovascular specific data, procedural data, financial and administrative data (e.g. cost of medications and supplies, length of stay, diagnosis codes etc.), short-to-long term clinical outcomes (including hospital re-admissions, cardiovascular events, death), and quality-of-care indices (e.g. compliance to guideline-recommended therapy and medications). The research project will involve all patients proven and/or suspected with coronary artery disease (CAD), congestive heart failure (CHF) and atrial fibrillation (AF) admitted to National Heart Centre Singapore (NHCS) and NUH.

NCT ID: NCT03759938 Not yet recruiting - Atrial Fibrillation Clinical Trials

OPTIMAS: OPtimal TIMing of Anticoagulation After Acute Ischaemic Stroke : a Randomised Controlled Trial

OPTIMAS
Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

OPTIMAS is a large, phase IV, prospective, partially blinded randomised controlled trial of early (within ≤4 days [96hrs]) or standard (between day 7 and day 14 after stroke onset) initiation of anticoagulation after stroke in patients with atrial fibrillation (AF), using any licensed dose of a direct oral anticoagulant (DOAC). The trial will use a non-inferiority gatekeeper approach to test for non-inferiority of early anticoagulation followed by a test for superiority, if non-inferiority is established.

NCT ID: NCT03759912 Recruiting - Atrial Fibrillation Clinical Trials

Ultra-High-Resolution Mapping Guided Partial Antral Ablation for AF

TAILOR
Start date: November 20, 2018
Phase:
Study type: Observational

The electrical isolation of the pulmonary veins (PVI) is the cornerstone of current ablation techniques for the treatment of atrial fibrillation (AF) because the PV is the most common trigger of AF. Wide bi-antral circumferential ablation (WACA) is more effective than segmental PV isolation in achieving freedom from total atrial tachyarrhythmia recurrence at long-term follow-up. Therefore, it is widely accepted as initial ablation strategy. However, the WACA technique requires a much larger number of ablation and higher energy to achieve complete isolation because of thick atrial myocardial sleeves with multiple muscle layers present in most of the PV antrum, which is less likely to achieve homogenous transmural lesions in the entire circumference with the currently available ablation technologies. Meanwhile, muscular discontinuities and abrupt changes of the fiber orientation in human PV-Left atrium (LA) junction are previously reported, and electrical PV isolation can usually be achieved without complete circumferential ablation. However, the current electroanatomical mapping (EAM) system has a limitation to understand the complex relationship of PV-LA junction mainly due to relatively low resolution. The Rhythmia mapping system (BostonScientific, Inc, Cambridge, MA) is a new system provides ultra-high-resolution EAM using a small basket array of 64 electrodes (IntellaMap Orion, Boston Scientific). Owing to better resolution, this new system capable of rapidly and accurately identify critical isthmuses and low-voltage regions of interest and also allows automatic acquisition and accurate annotation of the electrograms, without the need for manual correction. In this context, we hypothesized that rapid and precise identification of activation pattern of PV-LA junction by Rhythmia system could allow complete, durable electrical isolation of PVs without circumferential antral ablation.