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Stroke clinical trials

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NCT ID: NCT01289795 Recruiting - Ischemic Stroke Clinical Trials

Endothelial Function and Progenitor Cells in Acute Ischemic Stroke

EPCAS
Start date: July 2010
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether levels of circulating endothelial progenitor cells (cEPC) are increased in the acute phase of ischemic stroke.

NCT ID: NCT01288352 Completed - Stroke Clinical Trials

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial

EAST
Start date: July 1, 2011
Phase: Phase 4
Study type: Interventional

EAST prospectively tests the hypothesis that an early, structured rhythm control therapy based on antiarrhythmic drugs and catheter ablation can prevent atrial fibrillation (AF) related complications in patients with AF when compared to usual care. Patients will be randomized to early therapy or usual care. In the early therapy group, patients will receive either catheter ablation (usually by pulmonary vein isolation), or adequate antiarrhythmic drug therapy at an early time point. The initial therapy will be selected by the local investigator. Upon AF recurrence, both modalities will be combined. Usual care will be conducted following the 2010European Society of Cardiology ( ESC )guidelines for AF treatment. Early rhythm control therapy will be guided by Electrocardiogram (ECG) monitoring.

NCT ID: NCT01288040 Completed - Stroke Clinical Trials

Locomotor Training for Neurological Disease

Start date: January 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether split belt training can be used to treat walking pattern deficits from stroke and to determine whether different schedules and types of long term training on a custom split belt treadmill are likely to change/improve walking symmetry.

NCT ID: NCT01287975 Completed - Stroke Clinical Trials

Brain Computer Interface (BCI) Technology for Stroke Hand Rehabilitation

ARTS-BCI
Start date: January 2011
Phase: N/A
Study type: Interventional

This study is carried out to find out if Brain Computer Interface (BCI) technology or BCI technology coupled with robotic technology using a Haptic Knob will benefit patients with arm paralysis after stroke. BCI uses EEG-based motor imagery to detect user's thinking abilities which control motor movement. Haptic Knob is a novel robotic device, which specifically trains the wrist and hand with intensive repetitions in a supported environment.

NCT ID: NCT01287936 Completed - Clinical trials for Chronic Ischemic Stroke

A Study of Modified Stem Cells in Stable Ischemic Stroke

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The primary purpose of the clinical study is to determine the safety of a modified stem cell SB623 when administered to chronic, stable ischemic stroke patients. A second purpose is to determine whether SB623 might improve stroke symptoms. Chronic, stable ischemic stroke patients must be between 6 and 60 months after their stroke, and with only this one prior stroke, and with no further improvement from physical therapy.

NCT ID: NCT01284933 Completed - Stroke Clinical Trials

Carotid Plaque Imaging in Acute Stroke

CAPIAS
Start date: February 2011
Phase:
Study type: Observational

The purpose of this study is to determine the frequency, characteristics, and consequences of vulnerable carotid artery plaques ipsilateral to an acute ischemic stroke or TIA in the territory of the internal carotid artery.

NCT ID: NCT01283620 Completed - Stroke Clinical Trials

Atlantic Canada Modified Constraint Induced Movement Therapy Trial

Start date: December 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effectiveness and feasibility of a modified constraint induced movement therapy (mCIMT) intervention on upper limb function in two groups of patients acutely post-stroke; 1) an experimental group that will participate in a 10 week mCIMT intervention designed to improve upper limb function, in addition to usual care, and 2) a control group that will participate in a program of usual care consisting of a rehabilitation intervention for the affected upper limb that is dose-matched to the experimental group.

NCT ID: NCT01280006 Completed - Stroke Clinical Trials

Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.

NCT ID: NCT01278576 Completed - Stroke Clinical Trials

Botulinum Toxin A Adult Gastrocnemius Muscle Study

BTX-A
Start date: January 2011
Phase: Phase 4
Study type: Interventional

The study aims to compare the effectiveness of BOTOX-A® (botulinun toxin A) placed between two different injection sites, namely at the proximal portion of the gastrocnemius(GCM) versus at the midbelly of the GCM.

NCT ID: NCT01278498 Unknown status - Depression Clinical Trials

The Preventive Effect of Escitalopram on Depression and Related Emotional Disorders in Acute Stroke Patients

EMOTION
Start date: January 2011
Phase: Phase 4
Study type: Interventional

Through this study, the investigators are to demonstrate the superiority of Escitalopram over placebo for the prevention of poststroke depression in patients with acute stroke The primary hypothesis of this study is; This study will prove the superiority of Escitalopram on the prevention of poststroke depression in patients with acute stroke against placebo