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Stroke clinical trials

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NCT ID: NCT05032638 Completed - Stroke Clinical Trials

Adherence in Upper Extremity Home-based Rehabilitation

Start date: September 22, 2021
Phase: N/A
Study type: Interventional

The objective of the proposal is to determine the feasibility of implementing Ecological Momentary Assessment (EMA) and Motivational Interviewing (MI) methods to enhance adherence for a 4-week self-initiated arm training protocol. A non-randomized feasibility study using a 4-week UE training protocol will be conducted in 15 individuals within the first 12 months post-stroke living in the community. EMA data will be collected using a mobile app to automate real-time collection of adherence data on a daily basis. MI will be used to produce self-generated training plans (training goals, training schedule), guided by the therapist before the start of training.

NCT ID: NCT05032378 Enrolling by invitation - Stroke Clinical Trials

Motion Sensor and Feedback System Efficacy to Refine Movements After Injury

Start date: December 17, 2021
Phase:
Study type: Observational

The purpose of these case studies is to determine the efficacy of the Kinesthetic Awareness Training (KAT) device in facilitating the restoration of desired movement patterns when people with acquired central nervous system damage perform functional activities such as walking, transitioning from one position to another, or reaching with the arms.

NCT ID: NCT05032053 Recruiting - Ischemic Stroke Clinical Trials

Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds

AIM-2
Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

To observe the effect of different antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds. And further combined with proteomic methods to explore serological markers that can be used to accurately predict the prognosis of such patients.

NCT ID: NCT05031403 Recruiting - Stroke Clinical Trials

Development and Application of Tele-Neuro Rehabilitation System

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Disability due to neurological diseases is increasing in our country and world. With regular physiotherapy and rehabilitation, as well as patients' symptoms are brought under control, their affected functions in daily life are achieved and levels of independence and physical activity increase. Thus, the patients' quality of life and participation in social life is improved and patients are supported in physical, social and psychological terms. In recent years, it has been reported that exercise with telerehabilitation systems increase the compliance and participation of patients to the treatment, and even this system seems as effective as standard rehabilitation practices. Delivering the treatment through telerehabilitation system when that patients cannot receive it in the hospital due to epidemic, restriction, transfer difficulties, personal and environmental limitations will enable patients to receive the rehabilitation services.Telerehabilitation system is frequently encountered in the abroad, but there are limited systems with Turkish version specific to this patient group in our country. The aim of project is to develop and detect the efficiency of a telerehabilitation system which is used to assess, follow and design home-based rehabilitation program among individuals with chronic neurological diseases who have difficulty in participating in physiotherapy and rehabilitation services because of personal or environmental reasons.

NCT ID: NCT05030142 Recruiting - Clinical trials for Acute Ischemic Stroke (AIS) Related to a Distal Occlusion

Evaluation of Mechanical Thrombectomy in Acute Ischemic Stroke Related to a Distal Arterial Occlusion

DISCOUNT
Start date: November 14, 2021
Phase: N/A
Study type: Interventional

Mechanical thrombectomy (MT) has shown its effectiveness for the treatment of acute ischemic stroke (AIS) related to large vessel occlusion and rapidly became a cornerstone in the management of these patients. No strong evidence is available on the benefit of MT in AIS related to more distal occlusions. Some previous observational studies suggested a possible benefit but most of them were single-centre and retrospective studies providing a very low level of evidence. To date, no randomized controlled trial has been conducted in this indication, which represents 10% to 20% of all AIS involving intracranial vessel occlusions. This research is a multicenter open randomized controlled trial with two parallel groups : best medical treatment alone VS mechanical trombectomy + best medical treatment.

NCT ID: NCT05029414 Recruiting - Clinical trials for Acute Ischemic Stroke

EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke

DISTAL
Start date: December 9, 2021
Phase: N/A
Study type: Interventional

Acute ischemic stroke (AIS) is one of the main causes of disability and loss of quality adjusted life years. This study is to analyze whether endovascular therapy (EVT) in addition to best medical treatment (BMT) reduces the degree of disability and dependency in daily activities after a Medium Vessel Occlusion (MeVO) stroke compared to BMT alone.

NCT ID: NCT05029284 Completed - Stroke Clinical Trials

Behavioral Activation for Post-Stroke Sedentary Behavior Using Telehealth

teleABLE
Start date: December 20, 2021
Phase: N/A
Study type: Interventional

Adults with stroke-related disability spend more time sedentary than adults without stroke-related disability, which places them at risk for poor cardiovascular health outcomes. Few interventions are designed to reduce post-stroke sedentary time. The purpose of this research is to test whether the teleABLE (Activating Behavior for Lasting Engagement) Intervention is feasible and acceptable to adults within the first 12 months post-stroke. The hypothesis is that teleABLE can be feasibly delivered using videoconferencing within the first 12 months post-stroke. 10 participants will complete assessments and activity monitoring (activPAL micro3) at 0 (baseline) and 8 (post-intervention)-weeks. Participants will complete 12 sessions of the teleABLE intervention. Findings from this study will be used to guide the intervention protocol in the planned next phase of this research.

NCT ID: NCT05029193 Active, not recruiting - Stroke Clinical Trials

Effectiveness of Mindfulness After a Stroke

Start date: September 13, 2021
Phase: N/A
Study type: Interventional

Mindfulness is promising for individuals with neurological disorders and caregivers to improve psychological well-being. This study aims to determine the extent to which a 3-week online mindfulness intervention will improve quality of life and psychological well-being for chronic stroke survivors and their caregivers, compared to a waitlist control.

NCT ID: NCT05028868 Recruiting - Ischemic Stroke Clinical Trials

Clinical Research of Intravenous Thrombolysis for Ischemic Stroke in Northeast of China

CRISTINA
Start date: June 1, 2015
Phase:
Study type: Observational [Patient Registry]

This research is based on clinic treatment of intravenous thrombolysis for patients with acute ischemic stroke.By building up a database of these patients, the investigators aim to find some significance between groups by analyzing population information, clinical status and such for better evaluation and optimal treatment decision.

NCT ID: NCT05028855 Recruiting - Clinical trials for Cerebrovascular Stroke

Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis

CASCAS
Start date: January 14, 2017
Phase:
Study type: Observational [Patient Registry]

In this multi-center prospective observational study within a cohort of symptomatic cerebral atherosclerotic stenosis (sCAS) patients, 850 subjects were planed to be enrolled to explore the relationship between cerebral autoregulation (CA) and stroke recurrence, determine the threshold values of CA parameter for predicting stroke recurrence associated with particular stenosis.