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Stroke clinical trials

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NCT ID: NCT05657392 Recruiting - Stroke Clinical Trials

Quantitative EEG Changes Following Repetitive Transcranial Magnetic Stimulation in Patients With Post Stroke (EEG-rTMS)

EEG-rTMS
Start date: April 15, 2021
Phase: N/A
Study type: Interventional

Quantitative EEG (qEEG) has been used as an effective tool in the diagnosis and prognosis of brain-related diseases. In the literature, a variety of qEEG parameters have been proven informative in the prognosis of stroke. In addition, it has been demonstrated that changes in certain qEEG parameters during traditional/task-specific rehabilitation approaches are correlated with clinical outcomes of functional motor recovery. Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a non-invasive and therapeutic treatment used to accelerate and enhance the recovery process of motor function in stroke patients. Many studies have reported that inhibiting contralesional rTMS may have positive effects in stroke patients with severe upper extremity motor impairment. In this context, the aim of the proposed study is to investigate whether there is a correlation between the change in qEEG parameters and the improvement of motor functions associated with rTMS treatment and to provide an electrophysiological prognostic biomarker of inhibiting contralesional rTMS for stroke patients.

NCT ID: NCT05656638 Completed - Stroke Clinical Trials

Treatment of Grammatical Time Marking in Post-Stroke Aphasia

Start date: December 30, 2022
Phase: N/A
Study type: Interventional

The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs treated on the sessions. We also explore whether the observed progress can be transferred to untrained items, more ecological contexts and if is maintained two and four weeks after the end of treatment. This therapy will be administered to six individuals with brain lesions after stroke. Four individuals will take part of the individual therapy and two individuals will take part of the self-administered computer therapy. The therapy will last one month, at the rate of three weekly sessions of approximately one hour.

NCT ID: NCT05655039 Completed - Stroke Clinical Trials

The Effect of Pre-rehabilitation and Rehabilitation Period on Functional Status in Inpatient Stroke Patients

Start date: September 15, 2022
Phase:
Study type: Observational

Patients who underwent inpatient rehabilitation for the last 5 years were retrospectively scanned. The pre-rehabilitation and rehabilitation periods of the patients were determined. At the beginning and end of rehabilitation, patients were evaluated with the Brunsstrom, Barthel and Stroke Impact Scale. The effect of the specified durations on these scales was investigated.

NCT ID: NCT05654935 Withdrawn - Stroke Clinical Trials

Telerobotic Ultrasound for Carotid Imaging - Feasibility Study

Start date: March 26, 2014
Phase:
Study type: Observational

In this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in carotid plaque detection.

NCT ID: NCT05654350 Completed - Stroke Clinical Trials

Lesion Site and Neglect Anosognosia in Patients With Left Hemispatial Neglect

Start date: December 16, 2022
Phase:
Study type: Observational

The goal of this retrospective is to investigate the relationship between lesion site and neglect anosognosia in subacute or chronic right hemispheric stroke patients with left hemispatial neglect. The main questions it aims to answer are: - Was any lesion site related to a higher neglect anosognosia rate? - Did any lesion site related to a more severe neglect anosognosia? Participants will be divided into two groups regarding the presence of anosognosia for spatial neglect. Researchers will compare patients with and without anosognosia to see if any lesion site resulted in a higher anosognosia rate and more severe unawareness of neglect symptoms in daily life.

NCT ID: NCT05653466 Recruiting - Stroke Clinical Trials

Adaptive Trial Scheduling in Naming Treatment for Aphasia

Start date: December 6, 2023
Phase: Phase 2
Study type: Interventional

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life. This study is one of two that are part of a larger grant. This record is for sub-study 2, which will evaluate the benefits of adaptive trial spacing.

NCT ID: NCT05653440 Recruiting - Stroke Clinical Trials

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

Start date: November 27, 2023
Phase: Phase 2
Study type: Interventional

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life. This study is one of two that are part of a larger grant. This record is for sub-study 1, which will adaptively balance effort and accuracy using speeded naming deadlines.

NCT ID: NCT05653141 Recruiting - Clinical trials for Cognitive Performance

Post-stroke Cognitive Impairment

CogStroke
Start date: December 17, 2020
Phase:
Study type: Observational

Present study aims to track the post-stroke cognitive trajectories and to investigate its inter-individual variability.

NCT ID: NCT05652933 Recruiting - Stroke, Acute Clinical Trials

Optimizing Acute Ischemic Stroke Diagnostics Using Artificial Intelligence

AI-STROKE
Start date: December 10, 2021
Phase:
Study type: Observational [Patient Registry]

Prospective observational multi-center study with the aim to organise and simplify the care pathway through a pragmatic approach to acute stroke imaging powered by cutting edge advances in image processing and artificial intelligence.

NCT ID: NCT05652751 Recruiting - Ischemic Stroke Clinical Trials

Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but it has little effect on stroke because of the blood-brain barrier (BBB). Electroacupuncture (EA) has been used for stroke, while there is no significant clinical effect for recovery phrase. Consequently, we will conduct a multicentre, randomised, controlled, assessor-blinded clinical trial to assess the effectiveness and safety of EA combined with NGF treatment on ischemic stroke recovery.