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Hypertension clinical trials

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NCT ID: NCT05308823 Enrolling by invitation - Clinical trials for Idiopathic Intracranial Hypertension

Outcome of Cerebral Venous Sinuses Stenting on Idiopathic Intracranial Hypertension

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The aim of the work is to asses the positive effect of stenotic sinus segment stenting on idiopathic intracranial hypertension with headache and papilloedema.

NCT ID: NCT05205265 Enrolling by invitation - Heart Failure Clinical Trials

Rivet PVS Therapy in Group 2 PH-HFpEF

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

This clinical investigation is a prospective, multicenter, non-randomized, open-label, Early Feasibility Study to evaluate the safety, performance, and initial clinical efficacy of the Rivet PVS therapy in patients with symptomatic pulmonary hypertension.

NCT ID: NCT05184179 Enrolling by invitation - Hypertension Clinical Trials

Observational Study to Evaluate the Therapeutic Effectiveness and Safety of Olomax Tab

Start date: December 1, 2019
Phase:
Study type: Observational

Throughout this study, the efficacy and safety information of Olomax tablets will be collected from 24 weeks to 48 weeks(+8 weeks) The Data collection point is baseline, at more than 24 weeks, at more than 48 weeks(+8 weeks).

NCT ID: NCT05131074 Enrolling by invitation - Hypertension Clinical Trials

Collabree: A Remote Intervention to Improve the Regularity of Medication Intake

Start date: March 10, 2022
Phase: N/A
Study type: Interventional

This is a clinical study to improve the regularity of medication intake for high blood pressure. Adult women and men who are over 50 years old, who have received a prescription drug for high blood pressure from MediService, and who have to take at least 4 tablets per day (of which at least 1 dose of medication per day is for high blood pressure) can participate in this study. The investigators intend to examine whether Collabree, a mobile phone application, is effective in supporting patients with hypertension to more successfully following their therapy plan in order to improve the regularity of medication intake. The study includes a 90-day intervention phase and a 90-day follow-up. The study does not require any therapy adjustments and no visits to a study center are necessary. The participants conduct the study independently at home. Participants will also fill out questionnaires. Participants are randomly assigned to one of 3 groups in a ratio of 1: 1: 1. Two of these groups will receive the Collabree mobile phone application.

NCT ID: NCT05117762 Enrolling by invitation - Healthy Clinical Trials

A Validation Study of Selfie Technology for Assessment of Vital Signs

Start date: November 2, 2021
Phase:
Study type: Observational

The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory rate and blood pressure in adults.

NCT ID: NCT05057039 Enrolling by invitation - Hypertension Clinical Trials

The Study of Gut Microbiota in Hypertensive Patients

Start date: September 1, 2021
Phase:
Study type: Observational

Recent animal and human studies have found the relationship between the composition of the gut microbiota and hypertension, but some studies did not have a detailed evaluation of the diet content, which could be an important effect on gut microbiota. Moreover, most of these studies were finished in Western countries, in which the dietary patterns were significantly different from those in Chinese regions. This study intends to establish Taiwanese local data to explore the differences in the composition of gut microbiota among hypertensive patients and normotensive subjects.

NCT ID: NCT05047731 Enrolling by invitation - Hypertension Clinical Trials

Antihypertensive Deprescribing in Long-term Care

OptimizeBP
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

Frail older adults are commonly prescribed blood pressure medication, yet it is unclear if blood pressure medication is actually beneficial for them. Observational studies in this population suggest blood pressure medication has limited benefit and may even be harmful, including an increased risk for falls and cognitive impairment. Randomized controlled trials are needed to confirm this. This study is a randomized controlled trial of blood pressure medication deprescribing, amongst long-term care residents with systolic blood pressure lower than 135 mmHg. In the intervention group, with physician consent, the facility pharmacist or nurse practitioner will continually reduce antihypertensives provided an upper systolic threshold of 145 mmHg is not exceeded. The control group will receive usual care. The primary outcome is all-cause mortality but the study will also be tracking all-cause hospitalization or emergency room visits, hip fractures, falls, skin ulceration, renal insufficiency, cognitive and behavioural outcomes and costs of care. The hypothesis is that avoiding unnecessarily low systolic blood pressure is beneficial in a frail, end-of-life population.

NCT ID: NCT05004935 Enrolling by invitation - Hypertension Clinical Trials

The Effect of Beetroot Juice on Plasma Trimethylamine N-oxide Concentration

BRJ_TMAO
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The primary aim of the current study is to determine the effect of beetroot juice consumption on plasma trimethylamine N-oxide concentration. A secondary aims: exploring the effect of circulating trimethylamine N-oxide modification on plasma total antioxidant status, and measurement of changes in the skin nicotinamide-adenine dinucleotide reduced form (NADH) content during transient ischemia and reperfusion.

NCT ID: NCT04938167 Enrolling by invitation - Clinical trials for Hypoxemic Respiratory Failure

Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension

POST-IT
Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to evaluate two oxygen saturation goals for newborns with pulmonary hypertension. Participation in this research will involve random assignment to one of two oxygen saturation goals, review of the medical record and targeted echocardiograms.

NCT ID: NCT04545034 Enrolling by invitation - Hypertension Clinical Trials

Water Aerobics Session on Blood Pressure of Hypertensive Elderly.

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

This randomized controlled trial aimed to determine the subacute blood pressure effects of pharmacologically-treated elderly hypertensive patients after a single session of water aerobic exercise.