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Depression, Anxiety clinical trials

View clinical trials related to Depression, Anxiety.

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NCT ID: NCT03804242 Not yet recruiting - Depression, Anxiety Clinical Trials

Black Youth M.A.T.T.E.R: Positive Youth Development Group Intervention

Start date: April 2019
Phase: Early Phase 1
Study type: Interventional

One in three Black boys born today in the United States will be incarcerated at some point in their lifetime, compared to one in 17 White boys. Black males are more likely to be arrested, convicted, and given unfair sentences. Black youth comprise of 16% of the Nation's public schools, but account for 32% of suspended students. For over 30 years, research has consistently highlighted the disproportionately severe disciplinary practices used with Black male students.Consistent research demonstrates that students who are suspended or expelled tend to drop out of school and/or become incarcerated in a juvenile detention center. Black students may relate their racial-ethnic identity, such as their understanding of their race and ethnicity, to academic success. Moreover, their attitudes may result from the expectation of their teachers. It is imperative that advocates devoted to positive youth development intervene to this issue negatively affecting the well-being of Black youth. Under the mentorship of Caitlin Sayegh, Ph.D., postdoctoral fellow Tierra Ellis, Ph.D., has developed a 9-session group intervention called Black Youth M.A.T.T.E.R. (BYM), which aims to debunk mental health stigma, help children shift their cognitive distortions about education, and normalize their experiences through group activities, while introducing them to advocacy and self-empowerment. This intervention may decrease mental health symptoms, increase motivation to approach goal-oriented outcomes, and reverse internalized beliefs and attitudes which may foster more positive perceptions related to school.

NCT ID: NCT03798548 Completed - Depression, Anxiety Clinical Trials

Brief CBT for Patients Undergoing TAVR

Start date: January 15, 2015
Phase: N/A
Study type: Interventional

Adult patients scheduled to undergo TAVR were randomized to receive brief bedside cognitive behavioral therapy for depression/anxiety or treatment as usual.

NCT ID: NCT03786328 Completed - Depression, Anxiety Clinical Trials

An Outreach Collaborative Model for Early Identification and Treatment of Mental Disorder in Danish Workplaces

Start date: April 1, 2008
Phase: N/A
Study type: Interventional

Depression and anxiety are prevalent mental disorders among the working population with potentially high personal and financial cost. The aim of the study is to test the applicability of an outreach collaborative model for early identification and treatment of clinical and sub-clinical mental disorders among Danish employees. applicability was examined by I) investigating the fractions of identified and treated clinical and subclinical cases, II) describing the distribution and characteristics of cases identified and III) investigating the effect of allocated treatment. A longitudinal study design with four assessments over 16 months are applied. Six medium-large companies will be included, both public and private cooperations. Self-reporting questionnaires probing for psychopathology will be distributed to all employees in the six consecutively enrolled companies at the four time points. Employees meeting the screening criteria at T1 will be assessed diagnostically. Subjects diagnosed with a clinical mental disorder will be allocated to outpatient psychiatric treatment, and subjects with subclinical conditions will be allocated to preventive cognitive behavioural therapy. Follow-up is conducted 6 and 12 months after initiation of treatment. Participation in the study is voluntary at all levels. Written informed consent will be obtained from participant selected for diagnostic interview and treatment.

NCT ID: NCT03759054 Recruiting - Depression, Anxiety Clinical Trials

Cancer Patients in Clinical Trials and Their Relatives

Start date: April 10, 2017
Study type: Observational

Aims The aims of this study are: 1. To characterize patients' psychological well-being from the time they are referred to a phase I trial and determine risk factors for poor well-being. 2. To investigate perceived information, expectations and regret when a patient participate in a phase I trial. Materials and methods This study is a prospective cohort study based on longitudinal applied questionnaires. The questionnaire will consist of questionnaires measuring stress, anxiety, depression and health-related quality of life longitudinal through the course in the Phase I Unit. At the time of inclusion in a trial, there will be questions regarding perceived information and expectations. At the time of exclusion from trial, there will be questions regarding regret. The questionnaire will consist primarily of validated questionnaires. When a validated questionnaire does not exist, a previous applied questionnaire will be used to ensure comparison with data from other studies. Only a limited use of self-constructed single-items will be applied.

NCT ID: NCT03707522 Recruiting - Depression, Anxiety Clinical Trials

Growth Mindset Psychoeducation for Modifiable Risk Factors for CMD

Start date: June 19, 2018
Phase: N/A
Study type: Interventional

The present study aims to determine the effect of presenting psychoeducation emphasizing "growth-mindset," and information on modifiable risk factors (e.g., social contact, physical activity) on engagement with modifiable risk factors. The investigators hypothesize that psychoeducation emphasizing that mental health is malleable will increase the participant's engagement with risk factors outlined in the intervention.

NCT ID: NCT03694106 Not yet recruiting - Depression, Anxiety Clinical Trials

T.E.A.M. Feasibility and Efficacy Study 2.0

Start date: November 1, 2018
Study type: Observational

T.E.A.M. psychotherapy was developed by one of the founders of cognitive therapy, David Burns and builds on traditional CBT with an emphasis on T = Testing, E = Empathy, A = Agenda Setting (assessing and building motivation) and M = Methods (including cognitive and behavioral methods). Because TEAM therapy is a data-driven therapy, its delivery hinges on the use of symptom measures and measures of the therapeutic alliance at every session with every patient. These measures are now available for collection thru computerized forms, making their collection and review considerably more accessible and efficient for the patient and therapist. The following hypotheses will be tested: 1. TEAM psychotherapy using computerized measurement collection is safe and feasible. 2. TEAM psychotherapy using computerized measurement collection shows evidence of efficacy by exploratory non inferiority testing compared to benchmark studies with similar psychotherapeutic modalities 3. Evidence for efficacy is strong enough to justify pursuit of an experimental randomized controlled clinical trial of TEAM therapy for major depressive disorder versus treatment as usual.

NCT ID: NCT03625024 Not yet recruiting - Depression, Anxiety Clinical Trials

Quality Assurance of Cognitive-behavioral Therapy

Start date: August 2018
Study type: Observational

The study examines associations between competence in cognitive-behavioral therapy (CBT) and adherence to evidence-based generic CBT in therapists and treatment outcome in patients with depression or an anxiety disorder in psychiatric outpatient care.

NCT ID: NCT03621397 Recruiting - Quality of Life Clinical Trials

Online Spanish Cognitive Intervention Program for Spanish-Speaking Latino/Hispanic Subarachnoid Hemorrhage Patients

Start date: December 2018
Phase: N/A
Study type: Interventional

The purpose of this research study is to examine the effectiveness of an online Spanish cognitive intervention program in Latino/Hispanic Spanish-speaking subarachnoid hemorrhage patients. In particular, the researchers will examine whether cognitive impairments associated with a subarachnoid hemorrhagic event improve after completing the online cognitive intervention program. Secondary outcomes of the research study include examining whether there is an improvement in research participants' quality of life and psychological functioning as a result of the online Spanish cognitive intervention program.

NCT ID: NCT03595956 Not yet recruiting - HIV/AIDS Clinical Trials

Transgender Cohort Study of Gender Affirmation and HIV-related Health

Start date: January 2019
Study type: Observational

This observational research study will evaluate medical gender affirmation delivered in primary care as an intervention to reduce disparities in HIV-related outcomes (e.g., low rates of PrEP uptake for HIV-uninfected patients, high rates of viral suppression for HIV-infected patients) for transgender patients in two urban federally-qualified community health centers.

NCT ID: NCT03566069 Not yet recruiting - Depression, Anxiety Clinical Trials

Intranasal Oxytocin as Enhancer of Psychotherapy Outcomes in Severe Mental Illness

Start date: June 2018
Phase: Phase 2
Study type: Interventional

Intranasal administration of Oxytocin (OT) has been found to improve social communication skills and encoding of social cues. Studies indicate that the provision of OT enhances the ability to develop trust 1, to improve the benefits of social support during social stress induction tasks 2 and to increase positive communication during couples' conflict discussions 3. These studies, and many others, point to the potential beneficial effects of OT as a facilitator of relationship-focused processes such as psychotherapy. Studies assessing the effect of OT as a possible outcome enhancer in psychotherapy for clinical populations are scarce, and their findings are largely inconsistent 4. Reasons for this state of affairs include the complexity of recruitment in this population; the provision of single-dose OT, which tends to cause a lower and insufficient effect 5; and methodological constraints, such as the lack of a control group 6 or insufficient probing of interpersonal factors 7. In this study we intend to overcome these constraints by evaluating the impact of intranasal administration of OT in patients suffering from acute stages of anxiety and depression disorders and undergoing intensive, relationship-focused psychotherapy during psychiatric hospitalization. One-hundred-and-twenty admitted patients with anxiety and depression disorders will be randomized and double-blindly allocated to two groups: (a) psychotherapy + OT (n=60), and (b) psychotherapy + placebo (n=60). Patients will be followed for three weeks, beginning at the start of their hospitalization, and will be assessed for the severity of their anxiety and depression symptoms; their working alliance with their therapist; and their treatment outcome after each session. Psychotherapy will be delivered twice a week. Intranasal OT will be administered twice a day. This study can provide insights regarding the potential involvement of OT in the trajectories leading to the production of detectable changes in brain activity following psychotherapy. Additionally, it can support the development of an integrating model combining recent findings in psychotherapy research pertaining to the significant role of therapeutic alliance in psychotherapy outcome, and findings from neuroimaging studies. Finally, provision of OT as a psychotherapy enhancer can facilitate a rapid therapeutic response and subsequently replace aggressive psychiatric medication usage, needed to create a rapid decrease of distress during psychiatric admissions.