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Coronary Artery Disease (CAD) clinical trials

View clinical trials related to Coronary Artery Disease (CAD).

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NCT ID: NCT03354273 Recruiting - Clinical trials for Coronary Artery Disease (CAD)

An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)

Start date: June 8, 2018
Phase: Phase 3
Study type: Interventional

This is a Phase 3, prospective, open-label, international, multicentre study of Flurpiridaz (18F) Injection for PET MPI in patients referred for ICA because of suspected CAD.

NCT ID: NCT03072121 Not yet recruiting - Clinical trials for Coronary Artery Disease(CAD)

Curative Effect Evaluation of Shexiang Baoxin Pill on Coronary Artery Disease Not Amenable to Revascularization

Start date: June 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Shexiang Baoxin Pill is effective in the treatment of coronary artery disease not amenable to revascularization on the basis of western medicine therapy.

NCT ID: NCT03072082 Not yet recruiting - Clinical trials for Coronary Artery Disease(CAD)

Curative Effect Evaluation of Danlou Tablet on Coronary Artery Disease Not Amenable to Revascularization

Start date: June 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Danlou Tablet is effective in the treatment of coronary artery disease not amenable to revascularization on the basis of western medicine therapy.

NCT ID: NCT03021577 Recruiting - Clinical trials for Coronary Artery Disease (CAD)

Comparison of Orbital Versus Rotational Atherectomy Effects On Coronary Microcirculation in PCI

ORACLE
Start date: January 25, 2017
Phase: N/A
Study type: Interventional

The investigators hypothesize that the orbital atherectomy system (OAS), a newer generation atherectomy device, reduces the incidence of microcirculatory compromise as compared to older generation rotational atherectomy (RA) due to differences in the mechanism of athero-ablation.

NCT ID: NCT02984891 Active, not recruiting - Clinical trials for Coronary Artery Disease (CAD)

Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

Start date: October 2016
Phase: N/A
Study type: Observational

Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are standardly used and have been extensively studied separately to guide percutaneous coronary intervention and improve long-term outcomes. In this study, the investigators aim to directly compare high-definition IVUS images to OCT in the same patients to determine the differences between each modality as they relate to imaging coronary pathology, with the goal of determining which modality is most appropriate in particular clinical scenarios.

NCT ID: NCT02905214 Recruiting - Clinical trials for Coronary Artery Disease (CAD)

Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

Start date: January 2016
Phase: N/A
Study type: Observational

Postmarket surveillance in terms of the safety and efficacy of Sirolimus-eluting Coroflex ISAR Stent for the treatment of "real world" patients with de-novo and restenotic lesions after stand-alone angioplasty in coronary arteries.

NCT ID: NCT02873052 Enrolling by invitation - Atherosclerosis Clinical Trials

MyoVista Measurements in Patients With Atherosclerosis and CAD

Start date: September 2015
Phase: N/A
Study type: Observational

The MyoVista system is a novel electrocardiogram technology that provides nonā€invasive assessment of myocardial abnormalities by analyzing energy changes at the cellular level of the myocardium.

NCT ID: NCT02765568 Recruiting - Clinical trials for Coronary Artery Disease (CAD)

Investigating the Effects of Cardiac Rehabilitation eXercise Modalities on Physical and Mental Health Outcomes

CRX-Modalities
Start date: June 2016
Phase: N/A
Study type: Interventional

Coronary revascularization improves survival for patients with coronary artery disease. However,many patients are left with poor physical and mental health. Traditional cardiac rehabilitation involves moderate intensity continuous exercise (MICE). Alternatives to traditional cardiac rehabilitation programming may however provide superior understudied benefits to patients with poor physical and mental health. Nordic walking (NW) and high-intensity interval training (HIIT) are two examples of alternative programs for cardiac rehabilitation, which may provide superior physical and mental health benefits when compared to traditional MICE. The main purpose of this project is, therefore, to determine the short and long term physical and mental health benefits of alternative cardiac rehabilitation modalities, including NW and HIIT on exercise capacity, quality of life and depression after a 12-week program.

NCT ID: NCT02629575 Completed - Clinical trials for Coronary Artery Disease (CAD)

Coroflex ISAR 2000 Registry

ISAR2000
Start date: January 2014
Phase: N/A
Study type: Observational [Patient Registry]

Postmarket surveillance in terms of the safety and efficacy of Sirolimus-eluting Coroflex ISAR Stent for the treatment of "real world" patients with de-novo and restenotic lesions after stand-alone angioplasty in coronary arteries

NCT ID: NCT02624297 Recruiting - Clinical trials for Coronary Artery Disease (CAD)

Chemoreflex Control of Sympathetic Activity in Patients With Coronary Artery Disease

Start date: January 2014
Phase: N/A
Study type: Interventional

The investigators hypothesize that chemoreflex response of muscle sympathetic nerve activity (MSNA) during hypoxia and hypercapnia will be increased in coronary artery disease (CAD) patients and that the presence of obstructive sleep apnea (OSA) will potentiate these responses. And, that the exercise training would decrease the chemoreflex response of MSNA in these patients.