Clinical Trials Logo

Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

Filter by:

NCT ID: NCT04978519 Not yet recruiting - Prostate Cancer Clinical Trials

Effectiveness of Cryotherapy Study for Prostate Cancer

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This is a single-centre prospective, non-randomized trial to investigate the efficacy of cryotherapy in patients with localized prostate cancer.The aim of study is to investigate the safety profile of cryotherapy in the treatment of prostate cancer and to evaluate the oncological control of prostate cancer by means of cryotherapy focal treatment.

NCT ID: NCT04972097 Not yet recruiting - Prostate Cancer Clinical Trials

Pivotal Study of the NanoKnife System for the Ablation of Prostate Tissue

PRESERVE
Start date: September 2021
Phase: N/A
Study type: Interventional

Pivotal study to evaluate the use of the NanoKnife System as a focal therapy option for prostate cancer patients. This study will assess the safety and effectiveness of the device when used to ablate prostate tissue in intermediate-risk prostate cancer patients.

NCT ID: NCT04962269 Completed - Prostate Cancer Clinical Trials

Application of DWI in Diagnosis of Prostate Cancer

Start date: June 12, 2013
Phase:
Study type: Observational

This study compared the performance of different models of multiple b-value DWI in diagnosing prostate cancer.

NCT ID: NCT04960956 Suspended - Prostate Cancer Clinical Trials

Glycosylation of Exosomes in Prostate and Urothelial Carcinoma

Start date: October 13, 2016
Phase:
Study type: Observational

The purpose of this study is to collect a urine sample from patients with prostate and urothelial (bladder) cancer and healthy volunteers who do not have cancer, so that researchers can perform studies on microcellular structures called exosomes that may eventually lead to a new type of urinary biomarker test for prostate and urothelial cancer.

NCT ID: NCT04953351 Not yet recruiting - Prostate Cancer Clinical Trials

MRI-Ultrasound Fusion or Cognitive Registration in MR-targeted Prostate Biopsy

PROMUC
Start date: August 2021
Phase: N/A
Study type: Interventional

This randomized controlled trial aims to assess the detection rate of clinically significant and clinically insignificant cancer of MRI-ultrasound fusion targeted biopsy compared to cognitive registration targeted biopsy in men with clinical suspicion of prostate cancer who had no prior prostate biopsy.

NCT ID: NCT04946370 Not yet recruiting - Prostate Cancer Clinical Trials

Maximizing Responses to Anti-PD1 Immunotherapy With PSMA-targeted Alpha Therapy in mCRPC

Start date: June 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II study investigating the combination of 225Ac-J591 (a drug that can deliver radiation to prostate cancer cells) with pembrolizumab (immunotherapy, a drug that increases the immune system's ability to destroy cancer cells). This study will assess whether 225Ac-J591 + pembrolizumab + androgen receptor pathway inhibitor (ARPI) is more effective against prostate cancer than pembrolizumab + ARPI alone.

NCT ID: NCT04946214 Recruiting - Prostate Cancer Clinical Trials

A Behavioral Health Intervention Using Digital Technology in Radiation Therapy for Prostate Cancer Patients

HIDRATEPRO
Start date: May 26, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how to incorporate a smart water bottle to improve bladder filling for prostate cancer patients undergoing radiation therapy.

NCT ID: NCT04936334 Recruiting - Prostate Cancer Clinical Trials

The Role of 68Ga-PSMA-11 PET in Surgery Guidance in Prostate Cancer

Start date: June 15, 2021
Phase: Phase 2
Study type: Interventional

Obtain PSMA-PET imaging preoperatively and calculate performance for predicting extra-prostatic extension based on whole-mount pathology (gold standard). Quantify the frequency of proper treatment changes directed by PSMA-PET, focusing on appropriate preservation of surrounding structures important for genito-urinary function including: 1) Bladder neck, 2) Nerve bundles, 3) Urethral Sphincter (Figure 4). Directly compare PSMA-PET performance for predicting extra-prostatic extension to standard-of-care assessments. Assess quality of life changes from preoperative baseline.

NCT ID: NCT04936243 Not yet recruiting - Breast Cancer Clinical Trials

TIPOPS (Telemedicine vs In Person Oncology Patient Surveillance)

Start date: July 2021
Phase: N/A
Study type: Interventional

This research study is comparing telemedicine and face-to-face visits to understand patients' experiences with telemedicine versus face to face visits and to understand when it is and is not appropriate to conduct visits remotely

NCT ID: NCT04926181 Not yet recruiting - Prostate Cancer Clinical Trials

Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer

Start date: July 31, 2021
Phase: Phase 2
Study type: Interventional

Despite the low androgen receptor (AR) transcriptional activity of treatment-emergent small cell neuroendocrine prostate cancer, there is persistent AR expression observed in the majority of treatment-emergent small-cell neuroendocrine prostate cancer (t-SCNC) biopsies. This indicates that epigenetic dysregulation leads to reprogramming away from an AR-driven transcriptional program. Therefore, continuation of AR blockade in the form of apalutamide may provide additive benefit compared to immune checkpoint blockade alone. We hypothesize that the combination of apalutamide plus cetrelimab will achieve a clinically significant composite response rate with sufficient durability of response in mCRPC patients with evidence of treatment-emergent small cell neuroendocrine prostate cancer