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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT03529643 Not yet recruiting - Prostate Cancer Clinical Trials

Effect of Anesthetic Method on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the effect of anesthetic method on the optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic prostatectomy.

NCT ID: NCT03526510 Recruiting - Prostate Cancer Clinical Trials

Hypofractionated Boost vs Conventionally Fractionated Boost for Localized High Risk Prostate Cancer

Start date: June 2011
Phase: N/A
Study type: Interventional

Randomized trial comparing 2 external beam radiotherapy fractionation schemes in patients with localized high risk prostate cancer. Primary endpoint is acute toxicity.

NCT ID: NCT03525652 Recruiting - Prostate Cancer Clinical Trials

Therapeutic Vaccine Plus PD-1 Knockout in Prostate Cancer Treatment

Start date: February 22, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This study is to evaluate the safety and efficacy of a therapeutic vaccine in combination with PD-1 knockout T cells in the treatment of advanced prostate cancer.

NCT ID: NCT03525288 Not yet recruiting - Prostate Cancer Clinical Trials

PSMA-PET Guided Radiotherapy

PSMA-PETgRT
Start date: May 15, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

PSMA PET/CT has demonstrated higher sensitivity in detecting metastases than current imaging standard of care (CT and bone scan). [18F]DCFPyL is a promising high-sensitivity second generation PSMA-targeted urea-based PET probe. The hypothesis is that definitive radiotherapy (RT) informed by PSMA-PET findings will lead to improved cancer control outcomes compared to RT guided by conventional staging only. This study utilizes cmRCT design in companion to PERA (Partnership initiative for the Evaluation of technological innovation in Radiotherapy).

NCT ID: NCT03524391 Completed - Prostate Cancer Clinical Trials

Effect of Yoga Counselling on Quality of Life and Psychological Outcomes of Prostate Cancer Patients

Start date: February 12, 2016
Phase: N/A
Study type: Interventional

Cancer is second leading cause of death worldwide. The psychological issues are related to all stages of the disease affecting outcome of treatment and overall quality of life. The study evaluated the effectiveness of yoga counselling among prostate cancer patients on their quality of life and psychological outcomes.

NCT ID: NCT03520478 Not yet recruiting - Prostate Cancer Clinical Trials

A Study of SHR3680 in Treating Patients With Hormone Sensitive Prostate Cancer

Start date: May 30, 2018
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the safety and efficacy of SHR3680 with bicalutamide in the treatment of patients with hormone sensitive prostate cancer.

NCT ID: NCT03518606 Not yet recruiting - Breast Cancer Clinical Trials

Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours

MOVIE
Start date: June 20, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II national, multicentre, multiple cohort, prospective open-label, non-randomised and non-comparative study, to evaluate the safety and activity of metronomic oral vinorelbine associated with durvalumab + tremelimumab combination immunotherapy for the treatment of advanced solid tumours.

NCT ID: NCT03516110 Recruiting - Prostate Cancer Clinical Trials

Health Related Quality of Life and Multidimensional Evaluations of Prostate Cancer Subjects Aged ≥ 60 Years Initiating Gonadotropin-Releasing Hormone (GNRH) Agonist Therapy

PRISME
Start date: March 9, 2018
Phase:
Study type: Observational [Patient Registry]

The objective of the study is to compare the evolution over 6 months of Health-Related Quality of Life (HRQOL) among different age groups in subjects with prostate cancer treated with GnRH agonist therapy.

NCT ID: NCT03516045 Recruiting - Prostate Cancer Clinical Trials

A Study of 18F-AlF-NOTA-Neurotensin PET/CT for Imaging Prostate Cancer

Start date: April 23, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to investigate the clinical value of [18F]aluminum fluoride-1,4,7-triazacyclononane-1,4,7-triacetic acid-neurotensin(18F-AlF-NOTA-neurotensin)positron emission tomography / computed tomography (PET/CT) in patients with prostate cancer (PCa).

NCT ID: NCT03513211 Not yet recruiting - Prostate Cancer Clinical Trials

Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer

HITMAN-PC
Start date: May 30, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Recent pre-clinical work has suggested that Itraconazole has an anti-cancer effect that works synergistically with hydroxychloroquine. This may delay the need for androgen deprivation therapy (ADT) and its associated toxicities in men with biochemically recurrent (BCR) prostate cancer. This study aims to determine feasibility, safety and efficacy of suba-itraconazole (SI) in combination with hydroxychloroquine (HQ) in the treatment of biochemically recurrent (BCR) prostate cancer as means of delaying time to commencement of androgen deprivation therapy.