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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT06235112 Not yet recruiting - Clinical trials for Coronary Artery Disease

AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

AI INFORM
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

AI INFORM is a multicenter randomized trial that will test the hypothesis that providing clinicians information on the presence and amount of coronary artery calcifications (CAC), will result in initiation or intensification of preventive therapies. The study will use a cloud-based artificial intelligence (AI) platform (Nanox.AI) that can analyze non contrast chest CT and estimate the amount of CAC.

NCT ID: NCT06228456 Recruiting - Clinical trials for Coronary Artery Disease

Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention

Start date: April 1, 2024
Phase: Phase 4
Study type: Interventional

The proposed study aims to assess the antiplatelet effects of more potent oral P2Y12 inhibition with low-dose ticagrelor (60 mg bid) compared with standard of care clopidogrel in patients with a high ABCD-GENE score (≥10). We hypothesize that ticagrelor is associated with better pharmacodynamic effects (i.e., lower platelet reactivity and high platelet reactivity rates) compared with clopidogrel in stable coronary artery disease patients undergoing percutaneous coronary intervention with a high ABCD-GENE score.

NCT ID: NCT06226948 Active, not recruiting - Clinical trials for Coronary Artery Disease

Using the Visualization for Lifestyle Change in Patients at Risk of Cardiovascular Diseases

Start date: May 6, 2024
Phase: N/A
Study type: Interventional

In the framework of PhD research, the investigators will present a visualization of estimation of CVDs risk and the possibility of monitoring blood glucose levels in real-time. Based on the results, the investigators will assess the association of these with lifestyle change. The findings highlight the need for sufficiently reliable and high-quality evaluations of visualizations, technologies or applications used in the family medicine.

NCT ID: NCT06224101 Completed - Clinical trials for Coronary Artery Disease

Simulation Training For Invasive Cardiovascular Procedures

Heart-SIMS1
Start date: December 15, 2023
Phase: N/A
Study type: Interventional

28 sixth-year medical students will attend a theoretical learning session on coronary angiography. After they will be randomized in 2 groups: a conventional training (CT) group (n=14) and a simulation training (ST) group (n=14). CT group will visualize a video-recorded simulation procedure with duration of 20 minutes, while ST group will perform CA simulated training with SimulHeart in groups of two also for 20 minutes. Finally, after the training session, students' knowledge will be assessed through a theoretical multiple-choice exam and a practical evaluation in a catheterization laboratory using SimulHeart.

NCT ID: NCT06218485 Not yet recruiting - Clinical trials for Coronary Artery Disease

FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With Coronary Artery Disease

FLAVOUR III
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

To compare the clinical outcomes of fractional flow reserve (FFR)-guided strategy versus intravascular ultrasound (IVUS)-guided stent implantation after angiography-derived FFR-based decision-making.

NCT ID: NCT06217120 Not yet recruiting - Clinical trials for Heart Failure With Preserved Ejection Fraction

Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction

COL-Micro-HF
Start date: March 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the impact of colchicine on the change in coronary flow reserve (CFR), a marker for coronary microvascular dysfunction (CMD), compared to placebo in patients with heart failure and ejection fraction above 40% (including patients with improved EF).

NCT ID: NCT06216847 Not yet recruiting - Clinical trials for Coronary Heart Disease (CHD)

Clinical Outcomes of Patients With Coronary Artery Disease

COCAD
Start date: February 1, 2024
Phase:
Study type: Observational [Patient Registry]

Coronary heart disease (CHD) stands as a foremost contributor to global mortality, characterized by complex pathogenesis that renders conventional "one-size-fits-all" preventive strategies inefficient. Therefore, the investigators designed a prospective, multi-center cohort study among patients hospitalized due to either confirmed or suspected CHD, which aimed to establish a holographic data set for the diagnosis and treatment of CHD and explore the impact of critical therapeutic strategies in the real world on the clinical outcomes of CHD patients, providing evidence to optimize the management pathway.

NCT ID: NCT06214819 Recruiting - Clinical trials for Coronary Artery Disease

Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

To evaluate the stent endothelialization (> 20 microns) of VIVO ISARTM versus XIENCE SkypointTM stents at 1-month (very early strut covered) at follow-up by Optical Coherence Tomography (OCT) implanted IN THE SAME PATIENT during routine clinical practice.

NCT ID: NCT06214624 Enrolling by invitation - Clinical trials for Coronary Heart Disease

Exercise and Brain in Coronary Heart Disease

Heart-Brain
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

The Heart-Brain project is a randomized controlled trial designed to examine the effects of two different exercise programs of 12-week duration: 1) aerobic high intensity interval training (HIIT), and 2) aerobic HIIT plus resistance training, on brain health and other outcomes in coronary heart disease patients.

NCT ID: NCT06214247 Completed - Clinical trials for Coronary Artery Disease

Wedge NC - Scoring Balloon Dilatation Catheter

Start date: August 27, 2021
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of Wedge NC Scoring Balloon Dilatation Catheter for dilating coronary stenosis during PCI in comparison with a similar product on the market.