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Stroke clinical trials

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NCT ID: NCT00442845 Completed - Clinical trials for Diabetes Mellitus, Type 2

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST)

ACTFAST
Start date: January 2003
Phase: Phase 4
Study type: Interventional

Physicians tend to always use the lowest dose of statins to initiate therapy even in subjects who require large reductions in cholesterol. The study evaluates if selecting the starting dose based on baseline and target LDL-C cholesterol would provide better results (ie proportion of subjects resching target)

NCT ID: NCT00442325 Completed - Clinical trials for Diabetes Mellitus, Type 2

Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets

ACTFAST 2
Start date: January 2003
Phase: Phase 4
Study type: Interventional

European physicians tend to always use the lowest dose of statins to initiate therapy even in subjects who require large reductions in cholesterol. The study evaluates if selecting the starting dose based on baseline and target LDL-C cholesterol would provide better results (ie proportion of subjects resching target)

NCT ID: NCT00436592 Completed - Clinical trials for Cerebrovascular Accident

Safety and Efficacy of NeuroFlo in 8-24 Hour Stroke Patients

Flo 24
Start date: February 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and feasibility of the NeuroFlo™ catheter in treating patients with ischemic stroke whose last time symptom-free was between 8-24 hours prior to treatment. The NeuroFlo device is intended to increase blood flow to the brain and potentially reduce the damage caused by stroke.

NCT ID: NCT00435617 Completed - Clinical trials for Cerebrovascular Accident

Study of Hand Therapy 3 to 24 Months After Stroke

Start date: May 2005
Phase: N/A
Study type: Interventional

The primary aim of this study is to investigate the effectiveness of the use of a robotic hand therapy device in the home environment. We hypothesize that the therapy group will improve hand function more than a customary and usual care group.

NCT ID: NCT00432796 Active, not recruiting - Stroke Clinical Trials

PERIOP 2 - A Safety and Effectiveness of LMWH vs Placebo Bridging Therapy for Patients on Long Term Warfarin Requiring Temporary Interruption of Warfarin.

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine the effectiveness and safety of LMWH postoperative bridging therapy (standard of care) versus postoperative placebo bridging therapy (experimental arm)for patients with mechanical heart valves or atrial fibrillation or atrial flutter who are at high risk for stroke when warfarin is temporarily interrupted for a procedure.

NCT ID: NCT00432666 Completed - Clinical trials for Post-stroke Upper Limb Spasticity

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Post-stroke Spasticity of the Upper Limb

Start date: June 2006
Phase: Phase 3
Study type: Interventional

IncobotulinumtoxinA (Xeomin) is a botulinum toxin type A preparation free from complexing proteins, i.e. free from proteins other than the active toxin. Injected into the muscle, incobotulinumtoxinA (Xeomin) causes local weakening. Botulinum toxin type A is widely used for treatment of various neurological conditions. This study will investigate the efficacy and safety of incobotulinumtoxinA (Xeomin) in the treatment of post-stroke spasticity of the upper limb.

NCT ID: NCT00431821 Completed - Stroke Clinical Trials

Reshaping Exercise Habits and Beliefs (REHAB)

REHAB
Start date: October 2006
Phase: N/A
Study type: Interventional

Regular exercise has been demonstrated to improve muscle strength, balance, coordination as well as improve cardiovascular fitness levels and overall quality of life in stroke survivors. This study is designed to test the feasibility and effectiveness of a 12-week intervention to education and encourage stroke survivors to exercise following discharge from rehabilitation settings using a walking program and targeted functional activity homework.

NCT ID: NCT00430456 Completed - Stroke Clinical Trials

Treadmill Exercise Prescriptions to Improve Fitness Versus Ambulatory Function After Stroke.

STEPs
Start date: August 2006
Phase: Phase 1
Study type: Interventional

Individuals disabled by stroke are at risk of losing cardiovascular fitness and muscle due to disease. This worsens disability and can increase the risk of having another stroke or a heart attack. We would like to find out if and how different types of regular exercise (intense walking, long walking) can increase fitness, balance and improve walking function and activities of daily living in individuals who have suffered a stroke.

NCT ID: NCT00428480 Completed - Stroke Clinical Trials

Walking Study for Stroke Rehabilitation

SIRROWS
Start date: May 2007
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to determine the effects of reinforcement of walking speed on recovery of walking speed over the course of inpatient rehabilitation for people after stroke. The study will also examine the relationship between short distance walking speed and walking distance over a fixed time.

NCT ID: NCT00422474 Recruiting - Clinical trials for Cerebrovascular Accident

Prognostic Significance of the Baroreflex Sensitivity Changes After Acute Ischemic Stroke

Start date: January 2007
Phase: N/A
Study type: Observational

After acute stroke, baroreflex sensitivity (BRS) is impaired. This impaired acute stage BRS has been reported to be predictive of worsen outcome years after stroke in general. However, it is not very clear if the impaired acute stroke BRS would actually persist months after the acute stage. It is also not clear that such change, if any, would correlate with the functional outcome or prognosis after stroke. The trial is to investigate the longitudinal time course of BRS after ischemic stroke up to the 6th month post stroke and to see if there is any correlation of the changes in BRS with the functional outcome parameters using NIHSS and mRS scores throughout this period.