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Stroke clinical trials

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NCT ID: NCT02974283 Not yet recruiting - Stroke, Acute Clinical Trials

Protective Effects of Normobaric Hyperoxia on Blood Brain Barrier in Patients With Acute Ischemic Stroke

Start date: December 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to find out a serum marker for the evaluation of blood brain barrier damage based on animal experiments and investigate the effect of NBO(Normobaric hyperoxia)on blood brain barrier in the acute ischemic stroke patients who received r-tPA thrombolytic therapy.

NCT ID: NCT02956096 Not yet recruiting - Stroke Clinical Trials

Evaluation of Autonomic Modulation in Stroke After Transcranial Direct Current Stimulation and Treadmill Training

Start date: December 2016
Phase: N/A
Study type: Interventional

Introduction: Patients post-stroke may have autonomic dysfunction, with increased blood pressure, heart rate (HR) and increased risk of sudden death. Studies have shown that transcranial direct-current stimulation (tDCS) can modulate the autonomic nervous system in healthy subjects, but little is known about these effects in stroke. Objective: To evaluate the effect of tDCS after treadmill training in the autonomic nervous system modulation in patients post-stroke.

NCT ID: NCT02937025 Not yet recruiting - Stroke Clinical Trials

Study of Safety and Efficacy of a Left Atrial Appendage Occulder

Start date: January 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This study mainly evaluated the feasibility and safety of a kind of Left Atrial Appendage Occluders which is to prevent ischemic stroke caused by nonvalvular atrial fibrillation (AF)

NCT ID: NCT02929784 Not yet recruiting - Stroke Clinical Trials

tDCS to Treat Hemiplegic Shoulder Pain

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the possibility of treating Hemiplegic Shoulder Pain (HSP) using transcranial direct current stimulation (tDCS) in patients following stroke. The secondary aims are to see if this treatment affects motor function of the upper limb, to asses the different types of HSP and whether there is any correlation to the location and extent of the stroke.

NCT ID: NCT02913183 Not yet recruiting - Stroke Clinical Trials

Efficacy and Safety of Young Health Plasma on Acute Stroke

Start date: October 2016
Phase: Phase 2
Study type: Interventional

Stroke is one of the main severe disease of public health importance. Recent studies showed that old age is one of the most important factors in influencing the outcome of patients with acute stroke, and the young plasma can reverse age-related brain impairments in mice. Therefore, this pilot study aims to investigate whether young plasma is effective in alleviating brain injury and neurologic deficits induced by acute stroke in patients.

NCT ID: NCT02896348 Not yet recruiting - Stroke Clinical Trials

Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors

Start date: January 2024
Phase: N/A
Study type: Interventional

The goal of this study is to: 1. Assess the usability of the SynPhNe device in a home environment. 2. Evaluate the efficacy of the SynPhNe home use device to improve motor hand function in chronic stroke subjects when used with a few sessions of standard care, as compared to standard care alone.

NCT ID: NCT02855424 Not yet recruiting - Stroke Clinical Trials

The Effect of Leg Cycling Exercise Program at Low or Moderate Intensity for Individuals With Subacute Stroke

Start date: August 2016
Phase: N/A
Study type: Interventional

Poor cardiopulmonary endurance is observed in individuals with acute stroke, even in chronic. In addition, the poor fitness may obstacle activities of daily life, decrease activities of autonomic system, and increase risks of recurrent, therefore, the cardiopulmonary endurance training should be included into the early-stage rehabilitation program. The ergocycling training could improve cardiopulmonary endurance for individuals with stroke. Moreover, the low-intensity exercise training can increase the willingness, and it is safer than the moderate-intensity exercise training. However, it needs to be evaluated whether the low-intensity exercise training can bring sufficient benefits, compared to the moderate-intensity exercise training. Objectives of the study is to compare the exercise benefits between the low-intensity and moderate-intensity exercise training, and then these would offer optimal exercise prescription and considerations in clinical practice.

NCT ID: NCT02850198 Not yet recruiting - Ischemic Stroke Clinical Trials

A Randomized Controlled Study of the Effectiveness of Scalp Electroacupuncture in Improving Upper Limb Motor Function in Convalescent Phase of Ischemic Stroke.

Start date: August 2016
Phase: N/A
Study type: Interventional

This research is primary to compare effectiveness of scalp electroacupuncture and scalp acupuncture on motor function of the upper limb(UL) in convalescence phase of ischemic stroke. The clinical research is a randomized controlled trial (RCT),consisting of two arms of scalp electroacupuncture group and sham sclp electroacupuncture group to value difference of upper limb function after 4 weeks. The result indicates that scalp electroacupuncture is more sufficient to alter function. The purpose is to value effectiveness of scalp electroacupuncture on motor function of the upper limb in convalescence phase of ischemic stroke.

NCT ID: NCT02802956 Not yet recruiting - Stroke Clinical Trials

A Preliminary Feasibility Efficacy of Participation in Daily Life Promotion Program

Start date: June 2016
Phase: N/A
Study type: Interventional

Efficacy of Participation in Daily Life Promotion Program for Patients with Chronic Stroke

NCT ID: NCT02756494 Not yet recruiting - Ischemic Stroke Clinical Trials

Ischemic Stroke in Chinese Young Adults

Start date: April 2016
Phase: N/A
Study type: Observational

Stroke is the fifth leading cause of death in the United States and the leading cause of disability. However, in China, stroke is one of the most frequent causes of death and chronic disability. Ischemic strokes in adults younger than 45 years of age were regarded as a relatively uncommon event in the proportion of <5% of all ischemic strokes.