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Stroke clinical trials

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NCT ID: NCT02350283 Completed - Ischemic Stroke Clinical Trials

Endovascular Therapy for Acute Ischemic Stroke Trial

EAST
Start date: January 2015
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of Solitaire thrombectomy in Chinese patients with acute stroke within 12 hours of symptom onset.

NCT ID: NCT02349269 Completed - Stroke Clinical Trials

Postoperative Atrial Fibrillation and Long-term Survival

POAF
Start date: January 2012
Phase: N/A
Study type: Observational [Patient Registry]

The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.

NCT ID: NCT02347995 Recruiting - Stroke Clinical Trials

Resistive Training Combined With Nutritional Therapy After Stroke

REPS
Start date: August 24, 2015
Phase: N/A
Study type: Interventional

Stroke survivors experience severe muscle wasting during the chronic phase of recovery, with implications for strength, function and general health. Although resistive exercise training effectively combats this problem, it is unknown whether sub-optimal protein intake limits the observed gains in skeletal muscle growth. Skeletal muscle adaptations may occur when resistive training (RT) is combined with nutritional therapy in the form of post- exercise protein consumption. This study would be the first to directly compare RT+protein supplementation to RT+placebo (same calories as protein supplement) in those with chronic hemiparesis caused by stroke, providing evidence-based rationale for combination therapy in the clinical care of this population.

NCT ID: NCT02347358 Not yet recruiting - Clinical trials for Ischemic Cerebrovascular Accident

Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke

Start date: February 2015
Phase: Phase 2
Study type: Interventional

This study is to test a hypothesis that temporary implantation of JRecanTM blood flow recanalisation device within 6.5 hours of symptom onset of acute ischemic stroke due to a major intracranial artery occlusion following IV r-tPA can provide a greater rate of early successful recanalisation than treatment of IV r-tPA alone.

NCT ID: NCT02346851 Completed - Clinical trials for Post-Stroke Hemiplegic Shoulder Subluxation

The Effects of Accelerometer Triggered Functional Electrical Stimulation on Post-Stroke Hemiplegic Shoulder Subluxation

Start date: November 12, 2013
Phase: N/A
Study type: Interventional

Post stroke hemiplegia patient have shoulder subluxation in affected side. The investigators use functional electrical stimulation in posterior deltoid and supraspinatus for prevention and treatment. But the investigators hypothesis self triggered myoelectric stimulation system has more effective for shoulder subluxation. The purpose of this study is to compare post-stroke shoulder subluxation treatment FES and triggered FES.

NCT ID: NCT02346630 Withdrawn - Stroke Clinical Trials

Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation

Start date: March 2015
Phase: Phase 4
Study type: Interventional

Stroke is the leading cause of acquired long-term disability in adults in developed countries. Despite aggressive rehabilitation, lasting upper extremity impairment remains in the majority of stroke survivors. It is hypothesized that enhancing neuroplasticity through the combination of drug therapy and physical therapy could enhance outcomes for stroke survivors. The combination of levodopa and intensive physical therapy shows promise in enhancing the functional motor recovery of stroke patients during the sub-acute and chronic period without reported significant side effects. Robotic-aided training is a promising tool that has the potential to deliver high-intensity, task-oriented, reproducible therapy that can decrease the burden on a therapist. Since the evidence behind dopaminergic potentiation of neuroplasticity and stroke recovery is promising, it is the investigators aim to combine dopaminergic drug therapy with highly intensive robotic-assisted therapy to provide superior upper extremity functional recovery over traditional stroke rehabilitation.

NCT ID: NCT02346266 Enrolling by invitation - Stroke Clinical Trials

SMART (School-aged Children Making Healthy Choices And Recognizing sTroke)

SMART
Start date: November 2014
Phase: N/A
Study type: Interventional

A stroke awareness program for school-aged children to learn the signs/symptoms of stroke, teach their parents and make healthy life-style choices.

NCT ID: NCT02345525 Completed - Stroke Clinical Trials

Constraint-Induced Movement Therapy in Chronic Stroke Patients

Start date: August 2014
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the feasibility of a Home-based Constraint-Induced Movement Therapy (hCIMT) compared to a Modified Constraint-Induced Movement Therapy (mCIMT) delivered in a outpatient setting on upper limb motor recovery in stroke survivors.

NCT ID: NCT02344901 Completed - Clinical trials for Atrial Fibrillation and Flutter

ReAl-life Multicentre Survey Evaluating Stroke Prevention Strategies (RAMSES)

RAMSES
Start date: February 2015
Phase: N/A
Study type: Observational [Patient Registry]

The aim of this study is to evaluate the present status of stroke prevention strategies in patients with non-valvular atrial fibrillation (NVAF). Vitamin K antagonists (VKAs) have been the only available oral anticoagulant therapy for decades. Recently novel oral anticoagulants have emerged as an alternative for VKAs. This study is planned to evaluate the epidemiological characteristics, thromboembolic and bleeding risks, stroke prevention strategies and appropriateness of oral anticoagulant use in NVAF patients. Time in therapeutic range (TTR) is going to be calculated as the percent of visits in range (2-3) for warfarin patients. This is a national multicenter observational study in which Turkey is divided into seven regions. A proportional number of patients to the population of every region is planned to be included.

NCT ID: NCT02344433 Completed - Stroke Clinical Trials

Using Virtual Counselors to Overcome Genetic Literacy Barriers

VICKY
Start date: November 2016
Phase: N/A
Study type: Interventional

A Relational Agent (RA) "virtual counselor" (VICKY: VIrtual Counselor for Knowing Your Family History) has been developed to collect family health history information for common health conditions including heart disease, stroke, diabetes, hypertension and various cancers. In this study, the investigators will conduct a randomized controlled trial (RCT) to compare the efficacy of using VICKY to the existing My Family Health Portrait (MFHP) tool for collecting family health history information among an underserved primary care patient population. The primary aims of the study are to 1) evaluate the efficacy of VICKY versus MFHP for collecting accurate family health histories and 2) determine whether accuracy varies as a function of health literacy. This project will obtain validation data on the efficacy of both VICKY and MFHP for collecting accurate family history data among an underserved patient population, in two languages (English and Spanish). The study will determine whether a virtual counselor can overcome many of the existing barriers to using traditional web-based family history tools.