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Stroke clinical trials

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NCT ID: NCT03271788 Not yet recruiting - Stroke Clinical Trials

Can Stroke Patients and Their Caregiver Benefit From Additive Mindfulness Training

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The main purpose of the study is to find out if MBSR (Mindfulness) in addition to occupational therapy, can improve the therapeutic results in stroke-patients and help relatives of stroke patients to improve their quality of life.

NCT ID: NCT03268070 Not yet recruiting - Stroke Clinical Trials

Transcranial Magnetic Stimulation in Stroke Motor Rehabilitation Treatment

Start date: February 2024
Phase: N/A
Study type: Interventional

The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.

NCT ID: NCT03266731 Not yet recruiting - Stroke Clinical Trials

Role of Anti-platelet in Treatment of Acute Ischemic Stroke

Start date: January 4, 2018
Phase: N/A
Study type: Interventional

Role of anti-platelet in treatment of acute ischemic stroke to determine the safety of immediate anti-platelet therapy .that is started as soon as possible within the first 24 hours of the onset of symptoms.

NCT ID: NCT03263455 Not yet recruiting - Stroke Clinical Trials

Kinesio-Taping in Stroke Patients With Visuospatial Neglect

k-neglect
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Stroke is the second leading cause of death worldwide and the third most common cause of disability. The effects of stroke are variable and may include impairments in motor and sensory systems, emotion and neuropsychological deficits such as a disorder of spatial awareness known as unilateral spatial neglect (USN). Approaches to ameliorate USN could be categorized in interventions as involving either bottom-up or top-down processing. The specific mechanisms underlying these effects on a number of manifestations of the USN syndrome may include the restoration of defective representations of the side of space contralateral to the lesion (contralesional), and of the ability to orient spatial attention contralesionally, through complex patterns of activation of both the damaged right hemisphere, and the contralateral left hemisphere, with differences related to the specific stimulation delivered to the patient. In recent years, increasing cutaneous stimuli through neuromuscular kinesiotaping has been proposed to enhance somatosensory inputs (24) and such as method could have positive effects on USN. The aim of the present study was to assess the effect of KTM applied on the sternocleidomastoid muscle controlateral side of the lesions in improving USN deficits in individuals with stroke patient in sub-acute phase. The hypothesis is that the KTM application could improved cognitive tests for assessing USN, motor deficits and kinesthetic neck sensibility.

NCT ID: NCT03255408 Not yet recruiting - Stroke Clinical Trials

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Start date: January 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).

NCT ID: NCT03252626 Not yet recruiting - Stroke Clinical Trials

Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke

Start date: April 18, 2024
Phase: Phase 4
Study type: Interventional

Ischemic stroke has a variety of treatments and currently drug therapy is one of the main treatments.A number of clinical studies have proved that alprostadil (PGE1) has pharmacological effects of significant dilation of blood vessels, inhibition of plate aggregation, anti-atherosclerosis and increased cerebral blood flow.Evaluate the 90-days efficacy by comparing two groups of patients'(one with alprostadil,another with placebo) mRS.

NCT ID: NCT03247998 Not yet recruiting - Stroke Clinical Trials

GA vs. CS for Endovascular Stroke Therapy

Start date: August 31, 2017
Phase: N/A
Study type: Interventional

After a stroke caused by a blockage (clot) in a blood vessel in the brain, patients may have the clot removed by threading a catheter from the groin up to the affected area of the brain. An anesthesiologist is involved in the patient's care during this procedure to maximize patient safety and procedural efficiency. The options for anesthesia for this procedure are general anesthesia (where the patient is unconscious) or sedation (where the patient is in a relaxed, calm, sleepy condition). Currently, it is unclear which of these anesthetic options contributes to the best patient outcome. The investigators would like to investigate whether or not one method of anesthesia (general or sedation) is better to use than the other when removing the clot.

NCT ID: NCT03223220 Not yet recruiting - Clinical trials for Acute Ischemic Stroke

Quelling of Excitotoxicity in Acute Stroke With Ketamine

QUEST-KETA
Start date: July 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators plan to undertake a phase II study to investigate the efficacy and side effects of intravenous ketamine to reduce neuroexcitotoxicity, and thus provide neuroprotection in patients diagnosed with acute ischemic stroke.

NCT ID: NCT03219645 Not yet recruiting - Ischemic Stroke Clinical Trials

Ginkgo Diterpene Lactone Meglumine Injection on Platelet Reactivity in Acute Ischemic Stroke

GDPRS
Start date: July 15, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This study evaluates the addition of Ginkgo Diterpene Lactone Meglumine Injection to aspirin in the treatment of acute ischemic stroke.Half of patient will receive Ginkgo Diterpene Lactone Meglumine Injection(25mg once/day D1-D14) and aspirin(300mg loading dose,then 100mg once/day D2-D14) in combination, while the other half will receive aspirin(300mg loading dose,then 100mg once/day D2-D14).

NCT ID: NCT03184675 Not yet recruiting - Stroke Clinical Trials

The Effects of Functional Action-Observation Training on Gait Ability in Patients With Chronic Stroke

Start date: June 15, 2017
Phase: N/A
Study type: Interventional

This study aimed to examine the effects of functional action observation training on gait ability in chronic stroke patients.