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Stroke clinical trials

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NCT ID: NCT05560152 Not yet recruiting - Clinical trials for Ischemic Stroke, Acute

Analyzing the Pharmacodynamic Substances and the Effects of Yiqihuayu Decotion for Acute Ischemic Stroke (PHYSIS)

PHYSIS
Start date: September 25, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The main purposes of this trial are to analyze the pharmacodynamic substances and the effects of Yiqihuayu Decotion for acute ischemic stroke. The trial is a non-randomized, controlled clinical trial.

NCT ID: NCT05559398 Not yet recruiting - Stroke, Acute Clinical Trials

Glenzocimab for REperfusion in the Setting of Endovascular Therapy for Brain infarctioN: GREEN Study

GREEN
Start date: October 10, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Emergent reperfusion is the main goal for acute ischemic stroke therapy (AIS). Endovascular therapy (EVT) is recommended within 6 hrs of stroke onset, and up to 24 hrs following perfusion imaging criteria. Despite the major benefit associated with MT, more than 50% of the patients remain disabled at 3 months. Reperfusion rates after MT are critical to determine functional outcome. However, complete reperfusion is obtained in only 50 % of the patients, due to, at least in part, erratic emboli and/or no-reflow processes. The aim of this study is to evaluate the efficacy of glenzocimab in addition to EVT and compared to EVT plus placebo, whether or not associated with ntravenous thrombolysis (IVT), on functional outcome at day 90.

NCT ID: NCT05552885 Not yet recruiting - Stroke Clinical Trials

The Reliability and Validity of the Figure of 8 Walk Test and Double Task Figure of 8 Walk Test in Persons With Stroke

Start date: October 10, 2022
Phase:
Study type: Observational [Patient Registry]

The validity of the dual-task F8W test in predicting falls in older adults has been confirmed. As far as we know, there are no studies evaluating the validity and reliability of the dual-task F8W test in stroke patients. Therefore, the aim of the study is to evaluate the validity and reliability of the F8W and dual-task F8W test in stroke patients.

NCT ID: NCT05545605 Not yet recruiting - Ischemic Stroke Clinical Trials

Efficacy and Safety of Sodium Oligomannate in the Prevention of PSCI

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Post-stroke cognitive impairment (PSCI) is a common complication of stroke, and seriously affect the quality of survival and the survival time in patients with stroke, PSCI is still lack of effective prevention and treatment measures, the study found that gut microbiota are closely associated with stroke and cognitive diseases, sodium oligomannate can improve cognitive function of mild-to-moderate alzheimer's disease (AD) , The Expert Consensus 2021 on the Management of Post-stroke cognitive impairment states that the role of sodium oligomannate in PSCI needs to be investigated in large sample clinical trials. This study intends to explore the efficacy and safety of sodium oligomannate in the prevention of PSCI in patients with acute ischemic stroke and cognitive impairment, so as to provide a potential intervention for the prevention of PSCI.

NCT ID: NCT05536739 Not yet recruiting - Stroke Clinical Trials

Adaptive Hip Exoskeleton for Stroke Gait Enhancement

Start date: January 1, 2026
Phase: N/A
Study type: Interventional

This work will focus on new algorithms for robotic exoskeletons and testing these in human subject tests. Individuals who have previously had a stroke will walk while wearing a robotic exoskeleton on a specialized treadmill. The study will compare the performance of the advanced algorithm with not using the device to determine the clinical benefit.

NCT ID: NCT05535504 Not yet recruiting - Stroke Clinical Trials

The Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke

Start date: September 30, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of repetitive transcranial magnetic stimulation applied with an electromagnetic therapy stimulator 'ALTMS-A' for upper-limb motor function recovery with the sham control group for those who need upper-limb rehabilitation treatment for subcortical and brainstem stroke

NCT ID: NCT05534360 Not yet recruiting - Stroke, Acute Clinical Trials

Tenecteplase Treatment in Ischemic Stroke Registry

TETRIS
Start date: September 2022
Phase:
Study type: Observational [Patient Registry]

The Tenecteplase Treatment in Acute Ischemic Stroke (TETRIS) Registry is multicenter ambispective observational study of patients with acute ischemic stroke who received intravenous thrombolysis with Tenecteplase

NCT ID: NCT05531461 Not yet recruiting - Stroke Clinical Trials

Cognition and Imaging With Tigertriever

COGNITIVE
Start date: June 2023
Phase:
Study type: Observational [Patient Registry]

The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.

NCT ID: NCT05515419 Not yet recruiting - Stroke Clinical Trials

Allogeneic Cord Blood for Neurological Diseases in Adults

Start date: July 1, 2024
Phase: Early Phase 1
Study type: Interventional

This open label trial is conducted to investigate the efficacy and safety of allogeneic umbilical cord blood therapy for adult patients with neurological diseases.

NCT ID: NCT05508113 Not yet recruiting - Clinical trials for Post-ischemic Stroke Insomnia

Ozone Autohemotherapy for Ischemic Stroke Sleep Disorder

Start date: August 26, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to observe the efficacy and safety of ozonated autohemotherapy in patients of post-ischemic stroke insomnia and to explore its mechanism of action.