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Stroke clinical trials

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NCT ID: NCT04388995 Enrolling by invitation - Clinical trials for Fluid Responsiveness

SVV and PPV Predict Fluid Responsiveness in Mechanically Ventilated Elderly Patients Under General Anesthesia

Start date: May 12, 2020
Phase: N/A
Study type: Interventional

Although individualized or goal-directed approach has been advocated, a reliable index is still required to help monitor the volume status timely and efficiently. Dynamic indexes, such as pulse pressure variation (PPV) and stroke volume variation (SVV), have been shown to be clearly superior to more commonly measured static preload variables, such as pulmonary artery occlusion pressure (PAOP) and central venous pressure (CVP). The reliability of dynamic indexes in monitoring the volume status and predicting fluid responsiveness have been validated. Fluid optimization guided by SVV and PPV is beneficial to hemodynamic stability and can decrease mortality and reduce postoperative complications. However, the usefulness of dynamic indexes in elderly patients has not been previously investigated. This study aimed to evaluate whether dynamic indexes PPV and SVV can reliably predict fluid responsiveness in elderly patients, and to determine their thresholds in elderly patients.

NCT ID: NCT04388891 Completed - Stroke Clinical Trials

Clinical Feasibility of Minimally Supervised Therapy After Stroke With a Hand Rehabilitation Robot

Start date: August 11, 2020
Phase: N/A
Study type: Interventional

The ReHapticKnob is a robot for hand rehabilitation after stroke. We aim to investigate the feasibility of minimally supervised therapy with the ReHapticKnob with stroke patients in a rehabilitation clinic, evaluate the usability of the ReHapticKnob (user interface and implemented exercises which were adapted for independent usage), and quantify the dose of additional robotic therapy that patients perform in a minimally supervised setting. Minimally supervised therapy means that after a training phase, where the therapists teach to the patients how to perform the exercises with the robot, the patients can autonomously train with the robot during free time without being directly supervised. Our hypothesis is that minimally supervised therapy might be a possible way to increase therapy dose for stroke patients, with the potential to further improve recovery of hand function with minimal additional burden for therapists and for the healthcare system.

NCT ID: NCT04387747 Completed - Stroke Clinical Trials

Evaluation of Sarcopenia in Patients With Stroke

Start date: September 15, 2019
Phase:
Study type: Observational

The aim of this study is to investigate the prevalence of sarcopenia in stroke patients; to determine the relationship between sarcopenia and duration of stroke, age, gender, etiology of stroke, ambulation status, spasticity, nutrition and malnutrition

NCT ID: NCT04387474 Completed - Clinical trials for Hemiplegia Following Ischemic Stroke

The Effectiveness of Rehabilitation Training Based on Brain-computer Interface Technology to Improve the Upper Limb Motor Function of Ischemic Stroke.

REBUILT
Start date: May 10, 2020
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of rehabilitation training based on brain-computer interface in improving the upper motor function, self-care ability in daily life and quality of life in patients with ischemic stroke. This study adopts centralized uniform random 1:1 grouping, subjects will be randomly assigned to the experimental group and the control group. Randomization schemes are generated by statistical professionals using SAS software.

NCT ID: NCT04387162 Completed - Stroke Clinical Trials

Prism Adaptation in Left Brain Stroke

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Of the 15,000 Veterans who are hospitalized for stroke each year more than half experience spatial and motor impairments and pain. Spatial-motor-sensory problems limit functioning and independence, which is costly to Veterans, their families, and society. Currently, spatial-motor-sensory problems are targeted using different treatments. However, there is a treatment that has shown promise in simultaneously targeting spatial function, motor function and pain in right-brain stroke. The investigators propose to investigate the feasibility of using adapted spatial-motor sensory assessment and treatment procedures for Veterans with left-brain stroke who have language and cognitive impairment. The next step will be to conduct a large-scale study focused on this multi-target treatment for more efficient and effective stroke rehabilitation. The investigators expect this line of research to increase functioning, independence and quality of life in Veteran stroke survivors.

NCT ID: NCT04386863 Completed - Stroke Clinical Trials

Taxonomy of Neurorehabilitation Treatments and Outcome Measures: a Multicentre Italian Study

Start date: June 22, 2018
Phase:
Study type: Observational

The main aims of the observational study are to taxonomize the contents of rehabilitation understanding goals and treatments provided to people with Parkinson Disease(PD) and Multiple Sclerosis(MS) and Stroke and their impact on the outcomes

NCT ID: NCT04386525 Not yet recruiting - Ischemic Stroke Clinical Trials

Omega 3 and Ischemic Stroke; Fish Oil as an Option

OmegaStroke
Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

In this trial, The investigators are going to investigate the improvement of neurological functions and infarced area of the brain in ischemic stroke patients after ingestion of omega 3 products that have high concentrations of DHA and EPA in comparison to control group. The study will assess the improvement by computerized calculation of the size of the infarcted area before and after the intervention and neurological assessment tools. The researchers will follow the scientific and ethical regulations prevent any harmful effect on recruited subjects.

NCT ID: NCT04382963 Active, not recruiting - Stroke Clinical Trials

Stroke Prevention in the Wisconsin Native American Population

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

This project will develop a "Stroke Awareness Team" including training of Oneida Health Service Coaches working in partnership with the UW team for a population-based health awareness program. This team will develop a series of Oneida Nation Healthy Living and Stroke Awareness Events (from now on health events) to provide education as to the severity of the problem as well as our standard therapies for lifestyle change and risk factor avoidance. This will include education of the healthy members of the tribe including the children to identify signs of stroke and TIA in their elders as well as to develop healthy lifestyles at the earliest of ages to influence the elders to modify their risks.

NCT ID: NCT04380454 Recruiting - Stroke Clinical Trials

Biomechanical and Neural Mechanisms of Post-stroke Gait Training

Start date: March 16, 2021
Phase: N/A
Study type: Interventional

The study seeks to develop an understanding of how, why, and for whom fast treadmill walking (Fast) and Fast with functional electrical stimulation (FastFES) induce clinical benefits, allowing future development of cutting-edge, individually-tailored gait treatments that enhance both gait quality and gait function.

NCT ID: NCT04380363 Active, not recruiting - Stroke Clinical Trials

Safety and Usability of the Honda Walking Assist Device (HWA) in the Home Environment

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to verify the safety and validate the usability of the Honda Walk Assist (HWA) device in the home setting versus an exercise program without the device in a gym setting for individuals diagnosed with stroke. The investigators hypothesize that the HWA exoskeleton is a safe and effective device for use by individuals diagnosed with stroke in the home environment.