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Stroke clinical trials

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NCT ID: NCT03605381 Recruiting - Stroke Clinical Trials

MORbidity PRevalence Estimate In StrokE

MORe PREcISE
Start date: September 30, 2018
Phase:
Study type: Observational

Information regarding the likely progress of post-stroke symptoms is vitally important to stroke survivors to allow them to plan for the future and to adjust to life after stroke. Moreover, the prevalence of morbidity secondary to stroke is of central importance to Health Professionals to understand the prognosis of the disease in the patients under their care. Additionally, it will also allow commissioners of care, planners and third sector organisations to adapt to and answer the needs of a post-stroke population. Currently, the data collected by national audit programmes are concentrated on what can be termed 'process or process of care' data. The utility of these data are in the ability to audit the care received by stroke survivors on stroke units against evidenced standards for care, thus ensuring evidence based practice. Nevertheless, process of care is only one form of measuring stroke unit care and the audit programmes collect some limited functional status data, data relating to risk-factor co-morbidities and treatment received data. Therefore, the scope of this study is to build on the minimum data set currently collected and to collect post-stroke data in domains not currently collected. The International Consortium for Health Outcomes Measurement (ICHOM) takes important steps to collect data outside of process of care data such as a Patient Reported outcome data in their minimum outcome data set for stroke [currently under review].. Nevertheless, the ICHOM doesn't currently advocate the specific collection of data relating to cognitive impairment or emotional problems secondary to stroke. It is in these important aspects that this study will augment the data set currently advocated by ICHOM to collect data in the areas of cognitive impairment and emotional problems secondary to stroke. Therefore, the aim of this study is to quantify the prevalence of morbidity at six months post-stroke.

NCT ID: NCT03601702 Recruiting - Clinical trials for Acute Ischemic Stroke

EmboTrap ® II Revascularization Device (Neuravi) in Acute Ischemic Stroke

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The primary aim of Registrap study is to assess the safety and effectiveness of the EmboTrap®II Clot Retriever device (Neuravi) in patients with acute ischemic stroke from large vessel occlusion.

NCT ID: NCT03592563 Recruiting - Stroke Clinical Trials

CUHK Brain Health Longitudinal Study

BHS
Start date: July 1, 2019
Phase:
Study type: Observational

The goal of this study is to develop a large longitudinal cohort of individuals diagnosed with or at high risk for brain diseases (both neurological and psychiatric in nature), in order to identify risk factors that contribute to neurological and psychiatric diseases over time. The investigators seek to capture relevant information from medical records, electronically administered questionnaires and follow up phone-based interviews. The investigators expect to eventually have sufficient power from our dataset to examine risk factors for a variety of brain disorders, both individually and in aggregate. Our ultimate goal is to offer scientifically validated ways to preserve and promote brain health by working with our patients' needs and tracking their progress over time.

NCT ID: NCT03588780 Recruiting - Clinical trials for Acute Stroke With Large Vessel Occlusion

Stent Thrombosis After Tandem Lesions Thrombectomy

DST-TANDEM
Start date: August 6, 2018
Phase:
Study type: Observational

The aim is to describe the rate of delayed stent thrombosis after endovascular management of consecutive tandem lesions, in a patient series with systematic follow-up of stent patency. In addition, Investigatros aim to research baseline patient characteristics that are associated with a higher risk of delayed stent thrombosis and to evaluate the clinical consequences of stent thrombosis

NCT ID: NCT03583827 Recruiting - Stroke Clinical Trials

Motor Learning of Stroke Patients in Virtual Environments

Start date: February 10, 2014
Phase: N/A
Study type: Interventional

The aim of this study is to assess the motor learning of patients with chronic stroke in virtual environments. Half the patients will undergo conventional therapy and half virtual reality training using virtual game. The study will also include healthy individuals matched for age, sex, schooling and hand laterality.

NCT ID: NCT03580642 Recruiting - Stroke Clinical Trials

Decision Support System for Stroke Survivors

STARR
Start date: April 27, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the usability of the system and its accordance with the users' needs. This evaluation will consider the effectiveness and the efficiency of the system, as well as stroke survivors' satisfaction. The effectiveness and the efficiency of the system will be measured by: - The relationship between the control of stroke survivors' daily activities and their risk of having a secondary stroke, - The decrease of the need for caregivers, - And consequently an improvement in stroke survivors' self-management.

NCT ID: NCT03578250 Recruiting - Stroke Clinical Trials

Error Augmentation Training Post Stroke

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Post-stroke individuals continue to suffer from significant motor impairments years after the stroke. Motor recovery is usually limited to the first 6 month after the stroke, in which the majority of improvements occur at the first three months. Error augmentation (EA) training using a robotic apparatus was suggested to enhance motor recovery by exploiting the adaptation mechanisms within the intact cerebellum in individuals who sustained cortical stroke. The aim of this study is to investigate whether error augmentation training for the upper extremity may enhance motor recovery in individuals that sustained cortical stroke. Fifty post-stroke individuals will be randomaly assigned into either EA training (study group- SG) or robotic training in null field environment (control group- CG). Both groups will carry out the same treatment protocol on the robotic device in addition to the standard rehabilitation protocol of the rehabilitation center. Treatment protocol will be consisted of about six training sessions on the robotic device, taken twice or three times a week for two to three weeks. Each training session will be composed of 20-30 minutes upper extremity training with or without EA force field. Motor performance will be evaluated before and after the treatment protocol by the Fugl-Meyer Assessment scale.

NCT ID: NCT03571763 Recruiting - Ischemic Stroke Clinical Trials

The Impact of Anti-thrombosis on Cerebral Microbleeds and Intracranial Hemorrhage in Ischemic Stroke Patients

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this prospective cohort study is to investigate whether antithrombotic therapy in the secondary prevention of ischemic stroke increases the risk of the emerging CMBs and whether the change is associated with an increased risk of intracranial hemorrhage, providing an imaging evidence for individualized antithrombotic therapy in such patients.

NCT ID: NCT03570450 Recruiting - Stroke Clinical Trials

Regenerative Stem Cell Therapy for Stroke in Europe 1-RESSTORE1

Start date: June 2, 2018
Phase: Phase 1
Study type: Interventional

Stroke is the second leading cause of death in the world population. When not fatal, stroke often results in disability, and secondary health problems affecting not only patients but also their families. Building on emerging preclinical and pilot clinical evidences, RESSTORE will focus on the clinical assessment of regenerative cell therapy to improve stroke recovery and patients quality of life.

NCT ID: NCT03570060 Recruiting - Clinical trials for Ischemic Cerebrovascular Accident

Stepwise Screening for Silent Atrial Fibrillation After Stroke

SAFAS
Start date: April 1, 2018
Phase:
Study type: Observational

The main hypothesis of this work is that an approach combining clinical parameters and biomarker assays could improve the understanding and prediction of the occurrence of silent atrial fibrillation (AF) in the acute phase after stroke. In this prospective work, the investigators will rely on the Dijon Stroke Registry, which collects extensive clinical data for each patient hospitalized for a stroke. As part of this registry, patients are seen 6 months after stroke to assess their clinical status. This clinical follow-up will allow us to judge the evolution of the AF diagnosed during the acute episode at a distance.