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Prostate Cancer clinical trials

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NCT ID: NCT03005262 No longer available - Prostate Cancer Clinical Trials

MLN8237 for a Subject With Adenocarcinoma of the Prostate

Start date: n/a
Phase:
Study type: Expanded Access

To allow a patient continued access to MLN8237

NCT ID: NCT01777061 No longer available - Prostate Cancer Clinical Trials

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Start date: n/a
Phase:
Study type: Expanded Access

When evaluating prostate cancer patients for recurrent disease, computed tomography (CT), and magnetic resonance imaging (MRI) are both highly sensitive methods for detecting lymph nodes, but are not specific as to whether the lymph nodes are malignant or benign. While positron emission tomography (PET) utilizing radioactive glucose (FDG) has revolutionized staging, restaging, and monitoring response to therapy in many prevalent cancers such as breast, colorectal, esophageal, head and neck, lung, lymphoma, and melanoma, findings with prostate cancer have proven less sensitive because prostate cancer has a lower avidity for glucose. A newer PET isotope, utilizing acetate that is incorporated into the cell membrane of rapidly proliferating cells, has shown greater sensitivity than FDG in detecting prostate cancer. This study will assess the clinical effectiveness of utilizing [11C]Acetate PET scans in identifying recurrent prostate cancer.